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| 1 | Gut microbiome in acute pancreatitis:A review based on current literature显示文摘The gut microbiome is a complex microbial community,recognized for its potential role in physiology,health,and disease.The available evidence supports the role of gut dysbiosis in pancreatic disorders,including acute pancreatitis(AP).In AP,the presence of gut barrier damage resulting in increased mucosal permeability may lead to translocation of intestinal bacteria,necrosis of pancreatic and peripancreatic tissue,and infection,often accompanied by multiple organ dysfunction syndrome.Preserving gut microbial homeostasis may reduce the systemic effects of AP.A growing body of evidence suggests the possible involvement of the gut microbiome in various pancreatic diseases,including AP.This review discusses the possible role of the gut microbiome in AP.It highlights AP treatment and supplementation with prebiotics,synbiotics,and probiotics to maintain gastrointestinal microbial balance and effectively reduce hospitalization,morbidity and mortality in an early phase.It also addresses novel therapeutic areas in the gut microbiome,personalized treatment,and provides a roadmap of human microbial contributions to AP that have potential clinical benefit. | Bharati Kadamb Patel Kadamb H Patel Madhav Bhatia Shridhar Ganpati Iyer Krishnakumar Madhavan Shabbir M Moochhala | 2021 | World Journal of Gastroenterology2021，27，30： | 10 |
| 2 | Atrial tachyarrhythmia in adult congenital heart disease显示文摘The adult congenital heart disease(ACHD) population continues to grow and most cardiologists, emergency room physicians and family doctors will intermittently come into contact with these patients. Oftentimes this may be in the setting of a presentation with atrial tachyarrhythmia; one of the commonest late complications of ACHD and problem with potentially serious implications. Providing appropriate initial care and ongoing management of atrial tachyarrhythmia in ACHD patients requires a degree of specialist knowledge and an awareness of certain key issues. In ACHD, atrial tachyarrhythmia is usual y related to the abnormal anatomy of the underlying heart defect and often occurs as a result of surgical scar or a consequence of residual hemodynamic or electrical disturbances. Arrhythmias significantly increase mortality and morbidity in ACHD and are the most frequent reason for ACHD hospitalization. Intra-atrial reentrant tachycardia and atrial fibrillation are the most prevalent type of arrhythmia in this patient group. In hemodynamically unstable patients, urgent cardioversion is required. Acute management of the stable patient includes anticoagulation, rate control, and electrical or pharmacological cardioversion. In ACHD, rhythm control is the preferred management strategy and can often be achieved. However, in the long-term, medication side-effects can prove problematic. Electrophysiology studies and catheter ablation are important treatments modalities and in certain cases, surgical or percutaneous treatment of the underlying cardiac defect has a role. ACHD patients, especially those with complex CHD, are at increased risk of thromboembolic events and anticoagulation is usually required. Female ACHD patients of child bearing age may wish to pursue pregnancies. The risk of atrial arrhythmias is increased during pregnancy and management of atrial tachyarrhythmia during pregnancy needs specific consideration. | Arsha Karbassi Krishnakumar Nair Louise Harris Rachel M Wald S Lucy Roche | 2017 | World Journal of Cardiology2017，9，6： | 3 |
| 3 | Multiple mRNAs from the Punch locus of Drosophila melanogaster encode isoforms of GTP cyclohydrolaseⅠwith distinct N-terminal domains显示文摘 | MCLEAN J R KRISHNAKUMAR S O’DONNELL J M | 1993 | J Biol Chem1993，268，27： | 1 |
| 4 | Highly efficient, solar active, and reusable photocatalyst: Zr-loaded Ag-ZnO for reactive red 120 dye degradation with synergistic effect and dye-sensitized mechanism 显示文摘 | Subash B Krishnakumar B Swaminathan M | 2013 | Langmuir2013，29，3： | 1 |
| 5 | An Improved Set of a X Parameters for Fe Mg-Ca Garnets and Refinements of the Or thopyroxene-garnet Thermometer and the Orthopy roxene garnel plagioclase-quartz Barometer 显示文摘 | BHATTACHARYA A KRISHNAKUMAR K R RAITH M | 1991 | Journal of Petrology1991，32，3： | 1 |
| 6 | Creation of a bacterial cell controlled by a chemically synthesized genome 显示文摘 | Gibson D G Glass J I Lartigue C Noskov V N Chuang R Y Algire M A Benders G A Montague M G Ma L Moodie M M Merryman C Vashee S Krishnakumar R Assad-Garcia N Andrews-Pfannkoch C Denisova E A Young L Qi Z Q Segall-Shapiro T H Calvey C H Parmar P P Hutchison C A Smith H O Venter J C | 2010 | Science2010，329，5987： | 1 |
| 7 | Regeneration of the thallus of Monostroma oxyspermum(Chlorophyta) from protoplasts in axenic culture显示文摘 | Krishnakumar G R Addepalli M K Reddy C R K | 1999 | Phycologia1999，38，： | 1 |
| 8 | Reciprocal binding of PARP-1 and bistone H1 at promoters specifies transcriptional outcomes显示文摘 | Krishnakumar R Gamble M J Frizzell KM | | 0，，5864： | 1 |
| 9 | Creation of a bacterial cell controlled by a chemically synthesized genome显示文摘 | Gibson D G Glass J I Lartigue C Noskov V N Chuang R Y Algire M A Benders G A Montague M G Ma L Moodie M M Merryman C Vashee S Krishnakumar R Assad-Garcia N Andrews-Pfannkoch C Denisova E A Young L Qi Z Q Segall-Shapiro T H Calvey C H Parmar P P Hutchison | | 0，，： | 1 |
| 10 | In-situ observation of deep water corals in the northern Red Sea waters of Saudi Arabia显示文摘 | QURBAN M A KRISHNAKUMAR P K JOYDAS T V MANIKANDAN K P ASHRAF T T M QUADRI S 1 WAFAR M QASEM A CAIRNS S D | 2014 | Deep Sea Research Part I: Oceanographic Research Papets2014，89，： | 1 |
| 11 | Trace metal in beach sediments of Velanganni Coast, South India: Application of auto- clave leach method显示文摘 | Krishnakumar P Lakshumanan C Jonathan M P | 2013 | A rabion Journal of Geosciences2013，7，7： | 1 |
| 12 | INCREASED SIZE EX- CLLJSION LIMIT 2 encodes a putative DEVIl box RNA helicase involved in plasmodesmata functn during Arabidopsis embryogenesis 显示文摘 | Kobayashi K Otegui M Krishnakumar S | 2007 | Pianl Cell2007，，19： | 1 |
| 13 | SRPK1 : a cispl- atin sensitive protein expressed in retinoblastoma 显示文摘 | Krishnakumar S Mohan A Kandalarn M | 2008 | Pediatr Blood Cancer2008，50，2： | 1 |
| 14 | Analysis on the nature of thermally induced deformation in human dentine by electronic speckle pattern interferometry (ESPI) 显示文摘 | Kishen A Murukeshan V M Krishnakumar V | 2001 | J Dentistry2001，29，8： | 1 |
| 15 | Roller element bearing fault diagnosis using singular spectrum analysis 显示文摘 | Muruganatham B Sanjith M A Krishnakumar B | 2013 | Mechanical Systems and Signal Processing2013，35，： | 1 |
| 16 | Roller element bearing fault diagnosis using singular spec- trum analysis 显示文摘 | Muruganatham B Sanjith M & Krishnakumar B | 2013 | Mechanical Systems and Signal Pro- cessing2013，35，12： | 1 |
| 17 | Biofiltration of toluenecontaminated air using an agro by-product-basedfilter bed显示文摘 | Hima A M Haridas A | 2007 | Applied Microbiology and Biotechnology2007，74，1： | 1 |
| 18 | Roller element bearing fault diagnosis using singular spectrum analysis显示文摘 | Muruganatham B Sanjith M A Krishnakumar B | 2013 | Mechanical Systems and Signal Processing2013，35，12： | 1 |
| 19 | Upregulatlon of 5-I-IT2C receptors in hippoc ampus of pilocarpine-induced epileptic rats:antagonism by Bacopa monnieri 显示文摘 | Krishnakumar A Nandhu M S Paulose C S | 2009 | Epilepsy Behav2009，16，2： | 1 |
| 20 | Myopia and Digit Ratio in Medical College Students显示文摘 | Krishnakumar M Atheeshwar S Chandr~ekar M D | 2014 | PloS one2014，9，89： | 1 |
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