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| 1 | Over expression of resistin in adipose tissue of the obese induces insulin resistance显示文摘AIM: To compare resistin mRNA expression in subcutaneous adipose tissue (SAT) and its correlation with insulin resistance (IR) in postmenopausal obese women. METHODS: A total of 68 postmenopausal women (non obese = 34 and obese = 34) were enrolled for the study. The women of the two groups were age matched (49-70 years). Fasting blood samples were collected at admission and abdominal SAT was obtained during surgery for gall bladder stones or hysterectomy. Physical parameters [age, height, weight, body mass index (BMI)] were measured. Biochemical (plasma insulin and plasma glucose) parameters were estimated by enzymatic methods. RNA was isolated by the Trizol method.SAT resistin mRNA expression was done by real time- reverse transcription polymerase chain reaction (RT-PCR) by using Quanti Tect SYBR Green RT-PCR master mix. Data was analyzed using independent Student's t test, correlation and simple linear regression analysis. RESULTS: The mean weight (52.81 ± 8.04 kg vs 79.56 ± 9.91 kg; P < 0.001), BMI (20.23 ± 3.05 kg/m 2 vs 32.19 ± 4.86 kg/m 2 ; P < 0.001), insulin (8.47 ± 3.24 U/mL vs 14.67 ± 2.18 U/mL; P < 0.001), glucose (97.44 ± 11.31 mg/dL vs 109.67 ± 8.02 mg/dL; P < 0.001) and homeostasis model assessment index (2.01 ± 0.73 vs 3.96 ± 0.61; P < 0.001) were significantly higher in postmenopausal obese women compared to postmenopausal non obese women. The mean serum resistin level was also significantly higher in postmeno-pausal obese women compared to postmenopausal non obese women (9.05 ± 5.15 vs 13.92 ± 6.32, P < 0.001). Furthermore, the mean SAT resistin mRNA expression was also significantly (0.023 ± 0.008 vs 0.036 ± 0.009; P < 0.001) higher and over expressed 1.62 fold (upregulated) in postmenopausal obese women compared to postmenopausal non obese women. In postmeno-pausal obese women, the relative SAT resistin mRNA expression showed positive (direct) and significant correlation with BMI (r = 0.78, P < 0.001) and serum resistin (r = 0.76, P < 0.001). Furthermore, the SAT resistin mRNA expression in postmenopausal obese women also showed significant and direct association (r = 0.45, P < 0.01) with IR, while in postmenopausal non obese women it did not show any association (r = -0.04, P > 0.05). CONCLUSION: Increased SAT resistin mRNA expres-sion probably leads to inducing insulin resistance and thus may be associated with obesity-related disorders in postmenopausal obese women. | Sadashiv Sunita Tiwari S Dhananjai Bhola N Paul Sandeep Kumar Abhijit Chandra Mahendra PS Negi | 2012 | World Journal of Diabetes2012，3，7： | 10 |
| 2 | SWR1 Chromatin-Remodeling Complex Subunits and H2A.Z Have Non-overlapping Functions in Immunity and Gene Regulation in Arabidopsis显示文摘进由改变建筑群的 SWR1 染色质的 nucleosomes 的 histone 变体 H2A.Z 的加入是在真核细胞的基因规定的关键步。在 Arabidopsis, SWR1c 和 H2A.Z 被显示了控制位于开发和环境回答下面的基因表示。尽管他们在防卫被含有,在免疫的复杂子单元和 H2A.Z 的特定的角色很好没被理解。在这研究,我们分析了 SWR1c 子单元,光周期无关的早 FLOWERING1 (PIE1 ) ,肌动朊相关的 PROTEIN6 (ARP6 ) ,和 SWR1 建筑群的角色 6 (SWC6 ) ,以及 H2A.Z,在防卫和基因规定。我们发现 SWR1c 部件在抵抗起不同作用到不同病原体。PIE1 和 SWC6 功能以及 H2A.Z 的弄空的损失导致了减少的基础抵抗,当 ARP6 fucntion 的损失导致了提高的抵抗时。我们发现在 PIE1 和 SWC6 的变化导致了损害被触发受动器的免疫。在 SWR1c 部件和 H2A.Z 的变化也导致了损害 jasmonic acid/ethylene-mediated 免疫。染色体宽的表示分析同样在基因规定为 H2A.Z 和 SWR1c 部件揭示不同角色,并且在在表明小径的防卫之间的生气谈话的规定为 PIE1 建议一个潜在的角色。我们数据表演尽管他们是一样的建筑群的部分, Arabidopsis SWR1c 部件能在植物免疫和基因规定有非冗余的函数。 | Souha Berriri Sreeramaiah N Gangappa and S Vinod Kumar | 2016 | Molecular Plant2016，9，7： | 7 |
| 3 | Combustion synthesis of Ce^(3+), Eu^(3+) and Dy^(3+) activated NaCaPO_4 phosphors显示文摘The preparation of NaCaPO4 doped with rare earth (RE) ions Ce3+, Eu3+ and Dy3+ by combustion method was described. Under UV excitation (251 nm) of NaCaPO4:Ce3+ showsd emission (367 nm) in UV range. When NaCaPO4:Dy3+ phosphor was excited at 349 nm, the emission spectrum showed intense bands at 482 nm (blue) and 576 nm (yellow). In Eu activated NaCaPO4 phosphor, the emission spectrum showed a dominant peak at 594 nm (orange) while others were at 614 and 621 nm (red) when excited at 393 nm. The prepared phosphor was characterized by X-ray diffraction (XRD), scanning electron microscope (SEM) and photoluminescence (PL) measurement. Thus, the photoluminescence behavior of NaCaPO4:Ce3+ was strongly suggested for scintillator. Likewise, Eu3+ and Dy3+ activated NaCaPO4 phosphors were recommended for near-UV white light-emitting diodes (LEDs). | K N Shinde S J Dhoble Animesh Kumar | 2011 | Journal of Rare Earths2011，29，6： | 7 |
| 4 | Clinical implications of diabetes in chronic liver disease:Diagnosis,outcomes and management,current and future perspectives显示文摘Diabetes mellitus(DM)is common in liver cirrhosis(LC).The pathophysiological association is bidirectional.DM is a risk factor of LC and LC is a diabetogenic condition.In the recent years,research on different aspects of the association DM and LC has been intensified.Nevertheless,it has been insufficient and still exist many gaps.The aims of this review are:(1)To discuss the latest understandings of the association of DM and LC in order to identify the strategies of early diagnosis;(2)To evaluate the impact of DM on outcomes of LC patients;and(3)To select the most adequate management benefiting the two conditions.Literature searches were conducted using Pub Med,Ovid and Scopus engines for DM and LC,diagnosis,outcomes and management.The authors also provided insight from their own published experience.Based on the published studies,two types of DM associated with LC have emerged:Type 2 DM(T2 DM)and hepatogenous diabetes(HD).High-quality evidences have determined that T2 DM or HD significantly increase complications and death pre and post-liver transplantation.HD has been poorly studied and has not been recognized as a complication of LC.The management of DM in LC patients continues to be difficult and should be based on drug pharmacokinetics and the degree of liver failure.In conclusion,the clinical impact of DM in outcomes of LC patients has been the most studied item recently.Nevertheless many gaps still exist particularly in the management.These most important gaps were highlighted in order to propose future lines for research. | Diego García-Compeán Emanuela Orsi Ramesh Kumar Felix Gundling Tsutomu Nishida Jesús Zacarías Villarreal-Pérez Ángel N Del Cueto-Aguilera JoséA González-González Giuseppe Pugliese | 2022 | World Journal of Gastroenterology2022，28，8： | 4 |
| 5 | Frameworks of Non-Orthogonal Multiple Access Techniques in Cognitive Radio Communication Systems显示文摘Recently,the increasing demand of radio spectrum for the next generation communication systems due to the explosive growth of applications appetite for bandwidths has led to the problem of spectrum scarcity.The potential approaches among the proposed solutions to resolve this issue are well explored cognitive radio(CR)technology and recently introduced non-orthogonal multiple access(NOMA)techniques.Both the techniques are employed for efficient spectrum utilization and assure the significant improvement in the spectral efficiency.Further,the significant improvement in spectral efficiency can be achieved by combining both the techniques.Since the CR is well-explored technique as compared to that of the NOMA in the field of communication,therefore it is worth and wise to implement this technique over the CR.In this article,we have presented the frameworks of NOMA implementation over CR as well as the feasibility of proposed frameworks.Further,the differences between proposed CR-NOMA and conventional CR frameworks are discussed.Finally,the potential issues regarding the implementation of CR-NOMA are explored. | Prabhat Thakur Alok Kumar S Pandit G Singh S N Satashia | 2019 | China Communications2019，16，6： | 3 |
| 6 | A lupane derivative and the 13C-NMR chemical shifts lupanone from Pleurostylia opposita 显示文摘 | Dantanarayana A P Kumar N S | 1982 | Phytochemistry1982，21，8： | 2 |
| 7 | Assessing Reseller Performance from the Perspective of the Supplier显示文摘 | KUMAR N STERN L W ACHROL R S | 1992 | Journal of Marketing Research1992，29，5： | 1 |
| 8 | Changes in soil nutrient content and enzymatic activity under conventional and zero-tillage practices in an Indian sandy clay loam soil 显示文摘 | MINA B L SAHA S KUMAR N | 2008 | Nutrient cycling in Agroecosystems2008，82，： | 1 |
| 9 | Combretastatin A-4 analogs as anticancer agents显示文摘 | Chaudhary A Pandeya S N Kumar P | 2007 | Mini Rev Med Chem2007，7，12： | 1 |
| 10 | Mycoplasma pneumoniae and its role in asthma显示文摘 | Nisar N Guleria R Kumar S | 2007 | Postgrad Med J2007，83，4： | 1 |
| 11 | Review on TiC Reinforced Steel Composites 显示文摘 | Parashivamurthy K I KUMAR R K SEETHARAMU S HANDRASEKHARAIAH M N | 2001 | Journal of Materials Science2001，，36： | 1 |
| 12 | Aspiration cytology of focal xanthogranulomatous pyelonephritis:a diagnostic challenge显示文摘 | Kumar N Jain s | 2004 | Diagn Cytopathol2004，30，2： | 1 |
| 13 | Cytomorphologic study of Hashimoto/s thyroiditis and its serologic correlation: a study of 150 cases显示文摘 | Singh N Kumar S Negi VS | 2009 | Aeta2009，53，5： | 1 |
| 14 | MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods 显示文摘 | Tamura K Peterson D Peterson N Stecher G Nei M Kumar S | 2011 | Molecular Biology and Evolution2011，28，10： | 1 |
| 15 | Functional immunogenicity of baculovirus expressing Pfs25,a human malaria transmission-blocking vaccine candidate antigen显示文摘 | Mlambo G Kumar N Yoshida S | | 0，，43： | 1 |
| 16 | Anemia and hematoma volume in acute intracerebral hemorrhag显示文摘 | Kumar M A Rost N S Snider R W | 2009 | Crit Care Med2009，37，5： | 1 |
| 17 | Une weetc or nitro furantoin before pereutaneous nephrolithotomy signifi- cantly reduces upper tract infection and urosepsis: a prospective controlled study Urology显示文摘 | Bag S Kumar S Taneja N | 2011 | 77 ( 1 ) : 45-492011，77，1： | 1 |
| 18 | Ontogenetic development of digestive enzymes in yellowtail kingfish Seriola lalandi larvae 显示文摘 | Chen B N Qin J G Kumar M S | 2006 | Aquaculture2006，260，： | 1 |
| 19 | In vitro and in vivo studies on the antioxidant activity of fish peptide isolated from the croaker (Otolithes ruber)muscle protein hydrolysate 显示文摘 | Nazeer R A Kumar N S Jai G R | 2012 | Peptides2012，35，2： | 1 |
| 20 | MEGA5 : Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods 显示文摘 | Tamura K Peterson D Peterson N Stecher G Nei M Kumar S | 2011 | Molecular Biology and Evolution2011，28，： | 1 |
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