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| 1 | Total hip replacement for arthritis following tuberculosis of hip显示文摘AIM: To present the results of total hip arthroplasty(THA) for post tubercular arthritis of the hip joint.METHODS: Sixty-five patients(45 male, 20 female) with previously treated tuberculosis of the hip joint underwent cementless THA for post tubercular arthritis. The average age at the time of THA was 48 years(range 29 to 65 years). Erythrocyte sedimentation rate, C reactive protein, chest X-ray and contrast enhanced magnetic resonance imaging were done preoperatively to confirm resolution of the disease and to rule out any residual disease. Intra-operative samples were taken for microbiological examination, polymerase chain reaction(PCR) and histological examination. Patients were started on anti-tubercular drugs one week before the operation and continued for 6 mo post operatively. The patients were followed up clinically using the Harris hip score as well as radiologically for any loosening of the implants, osteolysis and any recurrence of tuberculosis. Any complications especially the recurrence of the infection was also recorded.RESULTS: The mean interval from completion of antitubercular therapy for tuberculosis to surgery was 4.2 years(range, 2-6 years). Preoperatively, 17 patients had ankylosis whereas 48 patients had functional but painful range of motion. The mean surgical time was 97 min(range, 65-125) whereas the mean blood loss was 600 m L(range, 400-900 m L). The average follow up was 8.3 years(range 6-11 years). The average Harris Hip score improved from 27 preoperatively to 91 at the final follow up. Seventeen patients had acetabularprotrusion which was managed with impaction grafting and cementless acetabular cup. The bone graft had consolidated in all these 17 patients at the follow up. Two patients developed discharging sinuses at 9 and 11 mo postoperatively respectively. The discharge tested positive for tuberculosis on the PCR. Both these patients were put on antitubercular therapy for another year. Both of them recovered and had no evidence of any loosening or osteolysis on X-rays. There were no other complications recorded.CONCLUSION: Total hip replacement restores good function to patients suffering from post tubercular arthritis of the hip. | Vijay Kumar Bhavuk Garg Rajesh Malhotra | 2015 | World Journal of Orthopedics2015,6,8: | 19 |
| 2 | Imaging evaluation of traumatic thoracolumbar spine injuries: Radiological review显示文摘Spine fractures account for a large portion of musculoskeletal injuries worldwide. A classification of spine fractures is necessary in order to develop a common language for treatment indications and outcomes. Several classification systems have been developed based on injury anatomy or mechanisms of action, but they have demonstrated poor reliability, have yielded little prognostic information, and have not been widely used. For this reason, the Arbeitsgemeinschaftfür Osteosynthesefragen(AO) committee has classified thorocolumbar spine injuries based on the pathomorphological criteria into3 types(A: Compression; B: Distraction; C: Axial torque and rotational deformity). Each of these types is further divided into 3 groups and 3 subgroups reflecting progressive scale of morphological damage and the degree of instability. Because of its highly detailed sub classifications, the AO system has shown limited interobserver variability. It is similar to its predecessors in that it does not incorporate the patient's neurologic status.The need for a reliable, reproducible, clinically relevant, prognostic classification system with an optimal balance of ease of use and detail of injury description contributed to the development of a new classification system, the thoracolumbar injury classification and severity score(TLICS). The TLICS defines injury based on three clinical characteristics: injury morphology, integrity of the posterior ligamentous complex, and neurologic status of the patient. The severity score offers prognostic information and is helpful in decision making about surgical vs nonsurgical management. | Shivanand Gamanagatti Deepak Rathinam Krithika Rangarajan Atin Kumar Kamran Farooque Vijay Sharma | 2015 | World Journal of Radiology2015,7,9: | 18 |
| 3 | Surgical treatment of proximal humerus fractures using PHILOS plate显示文摘ObjectiveTo 与经历了的 51 个病人打开的为近似肱骨 fractures.MethodsWe 的板考察了的近似肱骨的内部锁住系统(PHILOS ) 评估开的减小和内部固定的功能的结果和复杂并发症有在年之间的 PHILOS 板的减小和内部固定 2007 ~ 2012。与 38 的吝啬的年龄有 35 个男人和 16 个女人;年(范围 24-68 ) 。在年龄组有 41 个病人 < 60 在年龄组的年和 10 个病人 > 60 年。根据更旧姓的分类系统, 8, 15 和 23 个病人有 2 部分, 3 部分,和 4 部分破裂,分别地并且 5 个病人让 4 部分断裂脱臼。所有手术在我们的第三级的照顾损伤中心被执行。在最后的后续的肩膀的功能的评估用 Constant-Murley score.ResultsThe 平均数后续被做经期是 30 月(范围 12-44 月) 。二个病人被失去到后续。留下 49 个病人,所有破裂临床上并且放射学地被统一。放射学的联合的吝啬的时间是 12 星期(范围 8-20 星期) 。在最后的后续,吝啬的 Constant-Murley 分数是 79 (范围 50-100 ) 。结果在 25 个病人,是优秀的在 13 个病人好、在 6 个病人公平、在 5 个病人差。在后续期间,内翻足 malunion, subacromial 冲击的一个盒子,深感染的一个盒子, intraarticular 螺丝钉穿入的一个盒子和固定的失败的一个盒子的四个盒子被注意。avascular 坏死的没有盒子,硬件失败,松开的锁住的螺丝钉或不属于工会 noted.ConclusionPHILOS 在近似肱骨破裂提供稳定的固定。为了阻止潜在的复杂并发症,希望 avascular 坏死,保存肱骨的头的由脉管形成的过细的外科的解剖是必要的。 | GN Kiran Kumar Gaurav Sharma Vijay Sharma Vaibhav Jain Kamran Farooque Vivek Morey | 2014 | Chinese Journal of Traumatology2014,17,5: | 14 |
| 4 | On-table reconstruction and fixation of Mason type III radial head fractures显示文摘 | G.N. Kiran Kumar Gaurav Sharma Kamran Farooque Vijay Sharma Vaibhav Jain Ravijot Singh Vivek Morey | 2015 | Chinese Journal of Traumatology2015,18,5: | 12 |
| 5 | Magnesium matrix composites for biomedical applications:A review显示文摘In recent years,a new wave of bioactive,biocompatibility and biodegradable metallic materials were developed for orthopedic applications.Pure Magnesium,Magnesium alloys,Magnesium alloy-based composites are extensive material to the biomedical applications,by virtue of its high biocompatibility and reasonable strength.Pure magnesium,Magnesium alloys can corrode too fast during the physiological conditions and loses their properties before bone heal.The new era for the development of magnesium-based composites can satisfy the orthopedic applications.Magnesium-based composites,as bio-materials,can produce adjustable mechanical properties like Ultimate tensile strength,ductility,elastic modulus,and corrosion resistance in the physiological conditions.In the Mg based composites,the matrix materials are biomedical magnesium alloys base like Mg-Ca,Mg-Al,Mg-Zn,and Mg-REE alloy and The reinforcements are based on hydroxyapatite(HAP),calcium polyphosphate(CPP),andβ-tricalcium phosphate(β-TCP)particles.This comprehensive review is focused on different grades of biodegradable magnesium matrix composites including their mechanical properties and corrosion resistance. | Vijay Kumar Bommala Mallarapu Gopi Krishna ChTirumala Rao | 2019 | Journal of Magnesium and Alloys2019,7,1: | 12 |
| 6 | A Review on Pharmacological and Analytical Aspects of Diosmetin:A Concise Report显示文摘Plants have been used as a source for food material and natural remedies for the treatment of vast range of diseases.Nature provides us remedies for the treatment of various types of disorders ranging from simple ailments to complicated diseases.Plants are known to possess different pharmacological activities due to the presence of various phytoconstituents.Flavonoids are one of the main active phytoconstituents found in fruits,vegetables,wines,tea and cocoa.Flavonoids exhibit various pharmacological activities such as antioxidant,anti-inflammatory,anti-allergic,antibacterial,oestrogenic,cytotoxic antitumoural,hepatoprotective,antithrombotic and antiviral activity.Diosmetin(3',5,7-trihydroxy-4'-methoxyflavone),the aglycone part of the flavonoid glycosides diosmin occurs naturally in citrus fruit.Although it is found in herbal medicines and plays an important role in the treatment of various ailments,only limited scientific researches have been conducted.The aim of this review is to collect all available scientific literature published on diosmetin and combine it into this paper.This review contains an overview of pharmacological activities,isolation techniques and analytical techniques for diosmetin.Thus,valuable information provided in the present review will help researchers in developing alternative methods for the treatment of diseases from diosmetin. | Kanika Patel Manoj Gadewar Vijay Tahilyani Dinesh Kumar Patel | 2013 | Chinese Journal of Integrative Medicine2013,19,10: | 11 |
| 7 | Processing and design methodologies for advanced and novel thermal barrier coatings for engineering applications显示文摘 | Vijay Kumar Balasubramanian Kandasubramanian | 2016 | Particuology2016,14,4: | 11 |
| 8 | Acute femoral artery pseudoaneurysm due to lesser trochanter fragment: an unusual complication of an intertrochanteric fracture显示文摘大腿骨的动脉的假动脉瘤是 intertrochanteric 骨折的稀罕复杂并发症。大多数这些状况由于因医生之治疗而引的损伤或损伤本身并且被打乱的骨头碎片很少引起。这里,我们报导从更小的 trochanter 碎片的尖铁与表面的大腿骨的动脉的 pseudoaneurysm 尖锐地介绍了的一个 72 岁的人的一个案例。有盖住的 stent 的 pseudoaneurysm 的经皮的 endovascular 处理在一个迫切基础上被承担。五天以后,病人被操作在之上,更小的 trochanter 碎片通过一个前面的切口被切除, intertrochanteric 骨折用动态新潮的螺丝钉被修理。破裂在 10 个星期被统一。在 one-year’s 后续,没有接枝相关的复杂并发症。这个案例说明那有代替的更小的 trochanter 碎片的 intertrochanteric 破裂能与流血和大腿骨的动脉的 pseudoaneurysm 尖锐地介绍。 | Gaurav Sharma Ravijot Singh Atin Kumar Vijay Sharma Kamran Farooque | 2013 | Chinese Journal of Traumatology2013,16,5: | 11 |
| 9 | Minimally invasive osteosynthesis of distal tibial fractures using anterolateral locking plate: Evaluation of results and complications显示文摘 | Devendra Lakhotia Gaurav Sharma Kavin Khatri G.N. Kiran Kumar Vijay Sharma Kamran Farooque | 2016 | Chinese Journal of Traumatology2016,19,1: | 11 |
| 10 | Efficacy of Bacillus subtilis MBI 600 Against Sheath Blight Caused by Rhizoctonia solani and on Growth and Yield of Rice显示文摘Rice sheath blight disease(ShB),caused by Rhizoctonia solani,gives rise to significant grain yield losses.The present study evaluated the efficacy of Integral?,the commercial liquid formulation of Bacillus subtilis strain MBI 600,against rice ShB and for plant growth promotion.In greenhouse studies,four log concentrations of Integral(from 2.2×106 to 2.2×109 cfu/mL) were used as seed treatment(ST).After 25 d,seedlings were dipped(SD) into Integral prior to transplanting.At 30 d after transplanting(DAT),leaf sheaths were inoculated with immature sclerotia of the pathogen.At 45 DAT,a foliar spray(FS) with Integral was applied to some treatments.The fungicide control was 50% carbendazim at 1.0 g/L,and a nontreated control was also included.Overall,there were 10 treatments,each with five replications.ShB severity was rated at 52 DAT,and seedling height and number of tillers per plant were rated at 60 DAT.In 2009,two field trials evaluated Integral at 2.2×108 and 2.2×109 cfu/mL.Integral was applied as ST,and seedlings were produced in a nursery bed.After 32 d,seedlings were treated with Integral as SD and transplanted into 10 m2 blocks.Foliar sprays were given at 45 and 60 DAT.There were seven treatments,each with eight replications arranged as a factorial randomized complete block design.At 20 DAT,the plots were broadcast inoculated with R.solani produced on rice grains.Seedling height before transplanting,ShB severity at 90 DAT,and grain yield at harvest were recorded.Integral at 2.2×109 cfu/mL provided significant increase of seedling heights over other treatments under greenhouse conditions.The Integral treatments of ST + SD + FS at 2.2×109 cfu/mL significantly suppressed ShB over other treatments.In field studies,Integral provided significant increase of seedling height in nursery,and number of tillers per plant,compared with the control.ShB severity was significantly suppressed with higher concentrations of Integral compared to lower concentrations.Grain yield were the highest at an Integral concentration of 2.2×109 cfu/mL.Overall,Integral significantly reduced ShB severity,enhanced seedling growth,number of tillers per plant and grain yield as ST + SD + FS at the concentration of 2.2×109 cfu/mL under the conditions evaluated. | K. VIJAY KRISHNA KUMAR S. KR. YELLAREDDYGARI M. S. REDDY J. W. KLOEPPER K. S. LAWRENCE X. G. ZHOU H. SUDINI D. E. GROTH S. KRISHNAM RAJU M. E. MILLER | 2012 | Rice science2012,19,1: | 11 |
| 11 | Low-velocity pneumatic conveying in horizontal pipe for coarse particles and fine powders显示文摘First,the characteristics of low-velocity conveying of particles having different hardness are experimentally investigated in a horizontal pipelin in terms of flow pattern and pressure drop to show that the slug flow can be classified into two types depending on the settling of particles alon the pipeline,and the period is small for slug flow without the settled layer,which is called solitary slug flow.The pressure drop for soft particles shown to be larger than that for hard particles.Then,experimental results are presented on horizontal fluidized-bed conveying of fine powders t show that air release from the top surface of the conveying channel is an important factor for high mass flow rate of particles. | Yuji Tomita Vijay Kumar Agarwal Hiroyuki Asou Katsuya Funatsu | 2008 | Particuology2008,6,5: | 9 |
| 12 | Is prophylactic placement of drains necessary after subtotal gastrectomy?显示文摘AIM: To determine the evidence-based values of prophylactic drainage in gastric cancer surgery. METHODS: One hundred and eight patients, who underwent subtotal gastrectomy with D1 or D2 lymph node dissection for gastric cancer between January 2001 and December 2005, were divided into drain group or no-drain group. Surgical outcome and post-operative complications within four weeks were compared between the two groups. RESULTS: No significant differences were observed between the drain group and no-drain group in terms of operating time (171 ± 42 min vs 156 ± 39 min), number of post-operative days until passage of flatus (3.7 ± 0.5 d vs 3.5 ± 1.0 d), number of post-operative days until initiation of soft diet (4.9 ± 0.7 d vs 4.8 ± 0.8 d), length of post-operative hospital stay (9.3 ± 2.2 d vs 8.4 ± 2.4 d), mortality rate (5.4% vs 3.8%), and overall post- operative complication rate (21.4% vs 19.2%). CONCLUSION: Prophylactic drainage placement is not necessary after subtotal gastrectomy for gastric cancer since it does not offer additional benefits for the patients. | Manoj Kumarl Seung Bong Yangl Vijay Kumar Jaiswall Jay N Shahl Manish Shreshthal Rajesh Gongal | 2007 | World Journal of Gastroenterology2007,13,27: | 7 |
| 13 | Management of neglected cervical spine dislocation: a study of six cases显示文摘没有神经病学的赤字的六忽视的颈的脊骨脱臼的一个案例系列,它是管理了 operatively.MethodsThe 学习的 ObjectiveTo 报告从 2010 年 8 月被进行到 2011 年 12 月,案例从医药教育和研究的研究生研究所的门诊部被选择,印度。病人在 30 ~ 50 年的年龄组。所有病人经由前面、以后的 approaches.ResultsDuring 被操作立即的手术后的时期,五(83.33%) 病人们有正常神经病学的地位。有 C 5-C6 subluxation 的(16.67%)病人在在更低的手足的 2/5 和在在 C 6 level.ConclusionThere 下面的上面的手足的 3/5 的水平和马达功率是的 C 6下面与感觉损失开发了神经病学的赤字在对颈的脊骨的忽视的分散注意力的屈曲损害的颅骨拖拉的角色都没为更多推迟比 3 个星期。以后由前面的途径列在后面节省许多时间。如果两条途径将在一样的坐被做,其次地对乐器学没有需要。但是如果上演过程是 planed,以后的稳定被推荐,,有在神经病学的地位的恶化的风险。 | Vijay Goni Nirmal Raj Gopinathan Vibhu Krishnan Rajesh Kumar Avinash Kumar | 2013 | Chinese Journal of Traumatology2013,16,4: | 6 |
| 14 | Animal models of human colorectal cancer:Current status, uses and limitations显示文摘AIM: To make orthotopic colon cancer murine modelsa more clearly understood subject. The orthotopic tumor models have been found to be more relevant in replicating the human disease process as compared to heterotopic models, many techniques for making orthotopic colorectal murine models have been reported.METHODS: We evaluated the current literature for various reported orthotopic colon cancer models to understand their techniques, advantages and limitations. An extensive literature review was performed by searching the National Library of Medicine Database(Pub Med) using Me SH terms animal model; colon cancer; orthotopic model; murine model. Twenty studies related to colon cancer orthotopic xenograft model were evaluated in detail and discussed here. RESULTS: The detailed analysis of all relevant reports on orthotopic model showed tumor take rate between 42%-100%. While models using the enema technique and minimally invasive technique have reported development of tumor from mucosa with tumor take rate between 87%-100% with metastasis in 76%-90%.CONCLUSION: Over the years, the increased understanding of the murine models of human colon cancer has resulted in the development of various models. Each reported model has some limitations. These latest models have opened up new doors for continuing cancer research for not only understanding the colon cancer pathogenesis but also aid in the development of newer chemotherapeutic drugs as they mimic the human disease closely. | Vijay K Mittal Jasneet Singh Bhullar Kumar Jayant | 2015 | World Journal of Gastroenterology2015,21,41: | 5 |
| 15 | Discovery of natural berberine-derived nitroimidazoles as potentially multi-targeting agents against drug-resistant Escherichia coli显示文摘A series of natural berberine-derived nitroimidazoles as novel antibacterial agents were designed, synthesized and characterized by nuclear magnetic resonance(NMR), infrared spectra(IR), and high resolution mass spectra(HRMS) spectra. The antimicrobial evaluation showed that some target molecules exhibited moderate to good inhibitory activities against the tested bacteria and fungi including clinical drug-resistant strains isolated from infected patients. Especially, 2-fluorobenzyl derivative8 f not only gave strong activity against drug-resistant E. coli with the minimal inhibitory concentration(MIC) value of0.003 m M, 33-fold more active than norfloxacin, but also exhibited low toxicity toward RAW 264.7 cells and less propensity to trigger resistance. The aqueous solubility and Clog P values of target compounds were investigated to elucidate the structureactivity relationships. Molecular docking and quantum chemical studies for compound 8 f rationally explained its antibacterial effect. The further exploration of antibacterial mechanism revealed that the highly active compound 8 f could effectively permeabilize E. coli cell membrane and intercalate into DNA isolated from resistant E. coli to form 8 f-DNA complex that might block DNA replication to exert the powerful bioactivities. Compound 8 f could also selectively address resistant E. coli from a mixture of various strains. | Guo-Biao Zhang Swetha Kameswari Maddili Vijai Kumar Reddy Tangadanchu Lavanya Gopala Wei-Wei Gao Gui-Xin Cai Cheng-He Zhou | 2018 | Science China Chemistry2018,61,5: | 5 |
| 16 | 喹唑酮咪唑类化合物的设计、合成及其抗菌活性与靶向DNA研究显示文摘多药耐药菌的频繁出现已日益严重威胁人类健康,开发结构新型的抗菌药物已成为全世界战胜耐药菌的重要课题.本文设计合成了一系列具有抗微生物潜力的酰腙桥链的喹唑酮咪唑类新化合物,其结构经核磁共振氢谱(~1H NMR)、核磁共振碳谱(^(13)C NMR)和高分辨质谱(HRMS)进行表征.生物活性研究发现,一些目标化合物具有较好的抗微生物活性,特别是十八烷基衍生物6h和4-氟苄基取代的化合物7i,抗痢疾杆菌和大肠杆菌DH52的活性是氯霉素的2.5~3.3倍,抗黄曲霉菌活性是临床药物氟康唑的28和8.4倍.用紫外-可见光谱法进行了高活性化合物7i靶向DNA的初步研究,发现咪唑衍生物7i可嵌入小牛胸腺DNA形成7i-DNA超分子络合物,从而阻断DNA复制,展现出较好的抗细菌活性.分子模拟研究表明,活性分子7i与DNA碱基通过氢键结合.该类化合物作为新型抗真菌黄曲霉菌专一特效药及新型抗细菌药值得深入研究. | 曹泉诚 王辉 Tangadanchu Vijai Kumar Reddy Gopala Lavanya 蔡桂鑫 周成合 | 2017 | 中国科学:化学2017,47,7: | 5 |
| 17 | Comparative study of multiple cancellous screws versus sliding hip screws in femoral neck fractures of young adults显示文摘 | Mayank Gupta Rajendra Kumar Arya Satish Kumar Vijay Kumar Jain Skand Sinha Ananta Kumar Naik | 2016 | Chinese Journal of Traumatology2016,19,4: | 5 |
| 18 | Single image defogging by gain gradient image filter显示文摘Dear editor,With the advancements in computer vision applications, the image defogging methods have received a lot of consideration. Defogging methods are extensively utilized in civil and military areas such as target detection, traffic surveillance,remote sensing. | Dilbag SINGH Vijay KUMAR | 2019 | Science China(Information Sciences)2019,62,7: | 5 |
| 19 | One Pot Reduction of Imines Generated in-situ from Aldehydes and Amines by the NaBH4-InCl3 System显示文摘钠 borohydride 的联合和在 acetonitrile 还原剂 imines 的氯化物从醛和胺在原处形成了到第二等的相应 functionalised 和第三级的胺在的铟(III ) 的催化数量对好收益中等。引人注目是高度, chemoselective 反应面对象卤素那样的另外的功能的组被完成,碳碳两倍契约和氢氧根组。 | RAVI, Varala RAMU, Enugala VIJAY KUMAR, Ponnamaneni SRINIVAS RAO, Adapa | 2006 | Chinese Journal of Chemistry2006,24,6: | 4 |
| 20 | Reference quality assembly of the 3.5-Gb genome of Capsicum annuum from a single linked-read library显示文摘Linked-Read sequencing technology has recently been employed successfully for de novo assembly of human genomes,however,the utility of this technology for complex plant genomes is unproven.We evaluated the technology for this purpose by sequencing the 3.5-gigabase(Gb)diploid pepper(Capsicum annuum)genome with a single Linked-Read library.Plant genomes,including pepper,are characterized by long,highly similar repetitive sequences.Accordingly,significant effort is used to ensure that the sequenced plant is highly homozygous and the resulting assembly is a haploid consensus.With a phased assembly approach,we targeted a heterozygous F1 derived from a wide cross to assess the ability to derive both haplotypes and characterize a pungency gene with a large insertion/deletion.The Supernova software generated a highly ordered,more contiguous sequence assembly than all currently available C.annuum reference genomes.Over 83%of the final assembly was anchored and oriented using four publicly available de novo linkage maps.A comparison of the annotation of conserved eukaryotic genes indicated the completeness of assembly.The validity of the phased assembly is further demonstrated with the complete recovery of both 2.5-Kb insertion/deletion haplotypes of the PUN1 locus in the F1 sample that represents pungent and nonpungent peppers,as well as nearly full recovery of the BUSCO2 gene set within each of the two haplotypes.The most contiguous pepper genome assembly to date has been generated which demonstrates that Linked-Read library technology provides a tool to de novo assemble complex highly repetitive heterozygous plant genomes.This technology can provide an opportunity to cost-effectively develop high-quality genome assemblies for other complex plants and compare structural and gene differences through accurate haplotype reconstruction. | Amanda M.Hulse-Kemp Shamoni Maheshwari Kevin Stoffel Theresa A.Hill David Jaffe Stephen R.Williams Neil Weisenfeld Srividya Ramakrishnan Vijay Kumar Preyas Shah Michael C.Schatz Deanna M.Church Allen Van Deynze | 2018 | Horticulture Research2018,5,1: | 4 |