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7篇 您的检索式:作者名="L Samini"
    题名 作者 年代 出处 被引量
1Protective effect of melatonin against multistress condition induced lipid peroxidation via measurement of gastric mucosal lesion and plasma malondialdehyde levels in rats显示文摘AIM: To study the protective effect of a natural antioxi- dant, melatonin, against multistress condition induced lipid peroxidation via determination of gastric damage and plasma malondialdehyde (MDA) level by high perfor- mance liquid chromatography in rats. METHODS: We compared indomethacin-induced gas- tric damage and MDA plasma level in three groups of rats: unoperated, bile duct ligated and sham-operated and evaluated the role of the melatonin on gastric dam- age and plasma MDA level. Indomethacin and melatonin were injected intraperitoneally in doses of 50 mg/kg and 20 mg/kg, respectively. Animals were killed 4 h after in- domethacin injection. RESULTS: Indomethacin induced more severe gastric damage and plasma MDA level in bile duct ligated ani- mals was significantly higher (3.1 ± 0.04 μmol/L) than sham (2.8 ± 0.04 μmol/L) and unoperated animals (1.4 ± 0.08 μmol/L). Pretreatment with melatonin reduced indomethacin-induced gastric damage and plasma MDA level. CONCLUSION: Considering the results of this study, we suggest that in multistress conditions the intensity of gastric damage and the plasma MDA level are great and melatonin reduces the negative effect of lipid peroxida- tion and cell damage by oxidative stress in multistress conditions due to its antioxidizing activity.V Kiarostami L Samini M Ghazi-Khansari 2006World Journal of Gastroenterology2006,12,46:2
2Evidences for involvement of nitric oxide in the gastroprotective effect of bromocriptine and cyclosporin A on water immersion stress-induced gastric lesions显示文摘Samini M Moezi L Jabarizadeh N 2002Pharmacol Res2002,46,6:1
3Evidences for involvement of nitric oxide in the gastro protective affect of bromocriptine and cy-closporine A on water immersion stress-induced gastric lesions显示文摘Samini M Moezi L Jabarizadeh N 2002Pharmacia Res2002,46,6:1
4Evidences for involvement of nitric oxide in the gastroproteetive effect of bromocriptine and cyclospo- rine A on water immersion stress - induced gastric lesions显示文摘Samini M Moezi L Jabarizadeh N 2002Pharmacol Res2002,46,6:1
5Evidences for involvement of nitric oxide in the gastroprotective effect of bromocriptine and cyclosporine A on water immersion stress-induced gastric lesions显示文摘Samini M Moezi L Jabarizadeh N 2002Pharmacol Res2002,46,6:1
6Evidences for involvement of nitric oxide in the gastroprotective effect of bromocriptine and cyclosporine A on water immersion stress - induced gastric lesions 显示文摘Samini M Moezi L Jabarizadeh N 2002Pharmacol Res2002,46,6:1
7The interaction of cannabinoids and opioids on pentylenetetrazoleinduced seizure threshold in mice 显示文摘SHAFAROODI H SAMINI M MOEZI L 2004Neuropharmaeology2004,47,:1
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