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35篇 您的检索式:作者名="LAM Frank"
    题名 作者 年代 出处 被引量
1北美“轻型木结构”住宅建筑的特点显示文摘“轻型木结构”是北美住宅建筑的主要结构形式。本文介绍了这种结构形式在经济性能、施工安装等方面的优点 ,阐述了其屋面、墙体及楼面等结构体系的特点和构造方法 ,介绍了结构传力体系、主要采用的设计方法、防腐防火处理等 ,以期对中国“轻型木结构”何敏娟 Frank Lam 2004结构工程师2004,20,1:57
2木材在北美建筑结构中的应用显示文摘本文描述了木材作为结构用材的一些重要特性,如各向异性的强度性能、吸湿性对承载能力的影响等;详细介绍了北美建筑中常用的各种锯材、工程木制品的类别、特点、应用等。对结构师了解材料、选用材料、提高结构可靠性能、降低成本、减少资源耗用等都具有重要的参考价值。何敏娟 Frank Lam 2003特种结构2003,20,4:7
3Load-sharing mechanism in timber-steel hybrid shear wall systems显示文摘The lateral performance of timber-steel hybrid shear wall systems with regard to the interaction between the steel frame and the intill wood shear wall was investigated in this paper. A numerical model for the timber-steel hybrid shear wall system was developed and verified against test results. Design parameters, such as the lateral infill-to-frame stiffness ratio and the arrangements of wood-steel bolted connections were studied using the numerical model. Some design recommendations were also proposed based on the parametric analysis. In the hybrid shear wall system, the infill wood wall was found to resist a major part of the lateral load within relatively small wall drifts, and then the steel frame provided more lateral resistance. Under seismic loads, the infill wood wall could significantly reduce the inter-story drift of the hybrid system, and a complementary effect between the infill wood wall and the steel frame was observed through different lateral load resisting mechanisms, which provided robustness to the hybrid shear wall systems.Zheng LI Minjuan HE Frank LAM Minghao LI 2015Frontiers of Structural and Civil Engineering2015,9,2:5
4Fabrication of copper nanorods by low-temperature metal organic chemical vapor deposition显示文摘Copper nanorods have been synthe-sized in mesoporous SBA-15 by a low-temperature metal organic chemical vapor deposition (MOCVD) employing copper (II) acetylacetonate, Cu(acac)2, and hydrogen as a precursor and reactant gas, re- spectively. The hydrogen plays an important role in chemical reduction of oganometallic precursor which enhances mass transfer in the interior of the SBA-15 porous substrate. Such copper nanostructures are of great potentials in the semiconductor due to their unusual optical, magnetic and electronic properties. In addition, it has been found that chemically modi- fying the substrate surface by carbon deposition is crucial to such synthesis of copper nanostructures in the interior of the SBA-15, which is able to change the surface properties of SBA-15 from hydrophilic to hydrophobic to promote the adsorption of organic cupric precursor. It has also been found that the copper nanoparticles deposited on the external sur- face are almost eliminated and the copper nanorods are more distinct while the product was treated with ammonia. This approach could be achieved under a mild condition: a low temperature (400℃) and vac-uum (2 kPa) which is extremely milder than the con- ventional method. It actually sounds as a foundation which is the first time to synthesize a copper nanorod at a mild condition of a low reaction temperature and pressure.ZHANG Ying Frank Leung-Yuk Lam HU Xijun YAN Zifeng 2006Chinese Science Bulletin2006,51,21:3
5Comparison of Static and Dynamic Cerebral Autoregulation Measurements显示文摘Frank P. Tiecks Arthur M. Lam Rune Aaslid David W. Newell 1995Stroke A Journal of Cerebral Circulation1995,,:2
6Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair显示文摘Macrophage plasticity is critical for normal tissue repair following injury.In pathologic states such as diabetes,macrophage plasticity is impaired,and macrophages remain in a persistent proinflammatory state;however,the reasons for this are unknown.Here,using single-cell RNA sequencing of human diabetic wounds,we identified increased JMJD3 in diabetic wound macrophages,resulting in increased inflammatory gene expression.Mechanistically,we report that in wound healing,JMJD3 directs early macrophage-mediated inflammation via JAK1,3/STAT3 signaling.However,in the diabetic state,we found that IL-6,a cytokine increased in diabetic wound tissue at later time points post-injury,regulates JMJD3 expression in diabetic wound macrophages via the JAK1,3/STAT3 pathway and that this late increase in JMJD3 induces NFκB-mediated inflammatory gene transcription in wound macrophages via an H3K27me3 mechanism.Interestingly,RNA sequencing of wound macrophages isolated from mice with JMJD3-deficient myeloid cells(Jmjd3f/fLyz2Cre+)identified that the STING gene(Tmem173)is regulated by JMJD3 in wound macrophages.STING limits inflammatory cytokine production by wound macrophages during healing.However,in diabetic mice,its role changes to limit wound repair and enhance inflammation.This finding is important since STING is associated with chronic inflammation,and we found STING to be elevated in human and murine diabetic wound macrophages at late time points.Finally,we demonstrate that macrophage-specific,nanoparticle inhibition of JMJD3 in diabetic wounds significantly improves diabetic wound repair by decreasing inflammatory cytokines and STING.Taken together,this work highlights the central role of JMJD3 in tissue repair and identifies cell-specific targeting as a viable therapeutic strategy for nonhealing diabetic wounds.Christopher O.Audu William J.Melvin Amrita D.Joshi Sonya J.Wolf Jadie Y.Moon Frank M.Davis Emily C.Barrett Kevin D.Mangum Hongping Deng Xianying Xing Rachel Wasikowski Lam C.Tsoi Sriganesh B.Sharma Tyler M.Bauer James Shadiow Matthew A.Corriere Andrea TObi Steven LKunkel Benjamin Levi Bethany BMoore Johann EGudjonsson Andrew MSmith Katherine A.Gallagher 2022Cellular & Molecular Immunology2022,19,11:2
7渗透测试技术在计算机网络安全中的应用显示文摘一位著名的犯罪学家曾经这样讲过:如果要了解罪犯的想法,最好是用罪犯的思维去思考问题。这个原则用在计算机安全上面的话,就衍生出所谓的渗透测试技术。现在一些公司经常雇佣一些计算机专家对自己公司的网络进行善意的攻击。Frank Lam 朴辉 2003安防科技2003,,3:2
8Modeling Three-Dimensional Timber Light-Frame Buildings显示文摘Ming He Frank Lam Ricardo O 2001Journal of Structural Engineering2001,327,8:1
9Tuning of the structure and parameters of a neural network using an improved genetic algorithms显示文摘Frank H F Leung H K Lams S H Ling 2003EEE Trans Neural Networks2003,14,1:1
10Tuning of the structure and parameters of a neural net- work using an improved genetic algorithm 显示文摘FRANK H F LEUNG H K LAM S H LING 2003IEEE Trans on Neural Networks2003,14,1:1
11A two-dimensional spectrum for bistatic SAR processing using series reversion显示文摘Yew Lam Neo Frank Wong Ian G Cumming 2007IEEE Geoscience and Remote Sensing Letter2007,4,1:1
12Tuning of structure and parameters of neural network using an improved genetic algorithm显示文摘Frank H F Leumg Lam H K Ling S H 2003IEEE Trans on Neural Networks2003,14,1:1
13Cu/MCM-41 as atalyst for photochemically enhanced oxidation of phenol by hydrogen peroxide显示文摘Hu Xi-jun Lam Frank L Y Cheung Lok Mm 2001Catalysis Today2001,68,:1
14Drug discovery from natural products显示文摘Vincent P. Gullo James McAlpine Kin S. Lam Dwight Baker Frank Petersen 2006Journal of Industrial Microbiology & Biotechnology2006,,7:1
15Skeletonized Internal Thoracic Artery Harvest Reduces Pain and Dysesthesia and Improves Sternal Perfusion After Coronary Artery Bypass Surgery: A Randomized, Double-Blind, Within-Patient Comparison显示文摘Munir Boodhwani B Khanh Lam Howard J. Nathan Thierry G. Mesana Marc Ruel Wanzhen Zeng Frank W. Sellke Fraser D. Rubens 2006Circulation2006,,8:1
16Macro- void distribution analysis in strand - based wood composite using an X - ray computer tomography technique显示文摘Sugimori Masatoshi Lam Frank 1999J Wood Science1999,45,:1
17Calibration characteristics of a video dimension analyser (VDA) system显示文摘LAM T FRANK C SHRIVE N 1992J Biomeehanics1992,25,10:1
18Tuning of the structure and parameters of a neural network using an improved genetic algorithm显示文摘Frank H F Leung H K Lam S H Ling 2003IEEE Trans Neural Networks2003,14,1:1
19Experimental investigation on lateral performance of timber-steel hybrid shear wall systems 显示文摘HE M J LI Z LAM Frank 2014Journal of Structural Engineering ASCE2014,140,6:1
20Submassive hepatic necrosis distinguishes HBV-associated acute on chronic liver failure from cirrhotic patients with acute decompensation显示文摘Hai Li Qiang Xia Bo Zeng Shu-Ting Li Heng Liu Qi Li Jun Li Shu-Yin Yang Xiao-Jun Dong Ting Gao Stefan Munker Yan Liu Roman Liebe Feng Xue Qi-Gen Li Xiao-Song Chen Qiang Liu Hui Zeng Ji-Yao Wang Qing Xie Qin-Hua Meng Jie-Fei Wang Peter R. Mertens Frank Lam 2015Journal of Hepatology2015,,:1
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