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| 1 | Micromachining applications of porous silicon 显示文摘 | Steiner P Lang W | 1995 | Thin Solid Films1995，255，： | 3 |
| 2 | Comprehensive lifestyle intervention vs soy protein-based meal regimen in non-alcoholic steatohepatitis显示文摘BACKGROUND Non-alcoholic steatohepatitis(NASH) has become one of the leading causes of liver disease in the western world. In obese patients weight reduction is recommended. Up to now there are no specific guidelines for weight loss in order to reduce hepatic fat content.AIM To investigate the effects of a 24-wk guided lifestyle intervention program compared to a meal replacement regimen based on soy protein.METHODS Twenty-six subjects with NASH participated in a randomized single-center study. They were randomly assigned to either meal replacement group(MR-G)with soy-yogurt-honey preparation or to guided lifestyle change group(LC-G)with endurance activity and nutrition counselling. Serum alanine transaminase(ALT), aspartate transaminase(AST), lipid parameters, and adipokines were measured. Liver fat content and lipid composition were determined by magnetic resonance imaging and magnetic resonance spectroscopy. Body fat mass and lean body mass were assessed using Bod Pod? device. Pre-and post-intervention monitoring of parameters was performed. Statistical analyses were conducted with SPSS software, results were expressed as median(interquartile range).RESULTS Twenty-two subjects(MR-G, n = 11 and LC-G, n = 11) completed the study(9 women, 13 men; age 52.1(15.0) years, body mass index(BMI) 32.3(3.3) kg/m^2).In both groups a significant weight loss was achieved(MR-G:-6.4(3.6) kg, P <0.01; LC-G:-9.1(10.4) kg, P < 0.01). BMI dropped in both groups(MR-G:-2.3(1.5)kg/m^2, P = 0.003; LC-G:-3.0(3.4) kg/m^2, P = 0.006). Internal fat and hepatic lipid content were markedly reduced in both groups in comparable amount. There was a strong correlation between reduction in liver fat and decrease in ALT.Likewise, both groups showed an improvement in glycemic control and lipid profile. Changes in adipokines, particularly in adiponectin and leptin were closely related to intrahepatic lipid changes.CONCLUSION Comprehensive lifestyle intervention and meal replacement regimen have comparable effects on body and liver fat, as well as decrease in markers of hepatic inflammation among NASH patients. | Peter Deibert Adhara Lazaro Denise Schaffner Aloys Berg Daniel Koenig Wolfgang Kreisel Manfred W Baumstark Daniel Steinmann Martin Buechert Thomas Lange | 2019 | World Journal of Gastroenterology2019，25，9： | 3 |
| 3 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 4 | Early clinical worsening in patients with TIA or minor stroke: The Austrian Stroke Unit Registry显示文摘 | J Ferrari M Knoflach S Kiechl J Willeit S Schnabl L Seyfang W Lang | 2010 | Neurology2010，，2： | 2 |
| 5 | Mixture toxicity of nitrobenzene and trinitrobenzene using the marine bacterium Vibrio harveyl as the test organism显示文摘 | Thomulka K W Lange J H | 1997 | Ecotoxicity and Environmental Safety1997，36，2： | 2 |
| 6 | Sweet cherry fruit distribution and leaf populations: modeling canopy dynamics and management strategies显示文摘 | Lang G A Olmstead J W Whiting M D | 2004 | Aeta Hortic2004，636，： | 1 |
| 7 | Probable modern analogue of Kuroko-type massive sulfide deposits in the Okinawa Through back-arc basin显示文摘 | Halbach P Nakamura K W Lange J | 1989 | Nature1989，338，： | 1 |
| 8 | Real ileal protein and amino acid digestibilities in feedsruffs for growing pigs as determined with the 15N-isotope dilution technique显示文摘 | de Lange C F M Souffrant W B Sauer W C | 1990 | J Anim Sci1990，68，： | 1 |
| 9 | Engineering a recombinant Deinococcus radiodurans for ollganopollutant degradation in radioactive mixed waste environment 显示文摘 | LANGE C C WACKETT L P MINTON K W | 1998 | Nat Biotechnol1998，16，10： | 1 |
| 10 | Current practice of insulin pump therapy in children and adolescents - the Han- hover recipe显示文摘 | Danne T yon Schutz W Lange K | 2006 | Pediatr Diabetes2006，7，4： | 1 |
| 11 | High-resolution, contrast-enhanced magnetic resonance angiography with elliptical centric k-space ordering of supra-aortic arteries compared with selective X-ray angiography 显示文摘 | Wutke R Lang W Fellner C | 2002 | Stroke2002，33，6： | 1 |
| 12 | InterlabOratory variation of bio-chemical markers of bone turnover显示文摘 | Seibel M J Lang M Geilenkenser W J | | 0，，： | 1 |
| 13 | Interhemispheric subdural hematoma显示文摘 | LANG E W HOHENSTEIN C | 1998 | Nervenatzt1998，69，4： | 1 |
| 14 | Pro- duction and response of human prostate cancer cell lines to granulocyte macrophage-eolony stimulating factor显示文摘 | Lang S H Miller W R Duncan W Habib F K | 1994 | Int J Cancer1994，59，： | 1 |
| 15 | comparison of single and biplane ventriculography for determination of left ventricular volume and ejection fraction显示文摘 | BROBAN W C GLAMANN D B LANGE R A | 1992 | Am J Cardiol1992，69，15： | 1 |
| 16 | Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene显示文摘 | LANG F F YUNG W K RAJU U | 1998 | J Neurosurg1998，89，1： | 1 |
| 17 | Identification of cold acclimated genes in leaves of Citrus unshiu by mRNA differential display显示文摘 | LANG P ZHANG C K EBEL R C DANE F DOZIER W A | 2005 | Gene2005，359，： | 1 |
| 18 | Radar-Observed Characteristics of Precipitating Systems during NAME 2004显示文摘 | LANG T J AHIJEVYCH D A NESBITT S W | 2007 | J Climate2007，20，9： | 1 |
| 19 | A ptform for largescale graphene electronics-CVD growth of single-layer graphene on CVD-grown hexagonal boron nitride显示文摘 | Wang M lang S K lang W J | 2013 | Adv Mater2013，25，19： | 1 |
| 20 | EAE/ASE recommenda- tions for image acquisition and display using three - dimensional echocardiography显示文摘 | Lang RM Badano LP Tsang W | 2012 | Eur Heart J Cardiovasc Imaging2012，13，： | 1 |
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