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| 1 | Long-term prognosis in patients with severe late radiation enteropathy:A prospective cohort study显示文摘AIM: To assess persistent symptoms and mortality in a cohort of patients with severe (grade 3-4) radiation enteropathy,59 patients were followed up after 15-18 years. METHODS: Fifty-nine patients were prospectively enrolled by twelve surgical departments. Primary malignant disease,radiation therapy and surgical management were recorded at inclusion. The cause of death or persistence of symptoms was examined in public death records or by interview of survivors. RESULTS: Thirty-nine patients had received radiation therapy for gynaecological cancers,twelve for urological cancers,four for gastrointestinal cancers and four for other malignancies. Forty-five patients (76%) required surgical intervention. Complications occurred in 11 (25%) operated patients. Forty-seven patients had died at the time of follow-up,seven (12%) died as a direct result of radiation enteropathy,while radiation enteropathy contributed to death in an additional seven patients. Four of the twelve surviving patients suffered from chronic debilitating symptoms of radiation enteropathy,while three had moderate symptoms. CONCLUSION: Patients with severe delayed radiation enteropathy have a high risk of persistence of symptoms after surgery. At least one in ten patients dies from radiation-induced bowel injury. | Annette Larsen Jon B Reitan Steinar T Aase Martin Hauer-Jensen | 2007 | World Journal of Gastroenterology2007,13,26: | 4 |
| 2 | How should liver hypertrophy be stimulated?A comparison of upfront associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)and portal vein embolization(PVE)with rescue possibility显示文摘Background:The role of associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)in comparison to portal vein embolization(PVE)is debated.The aim of this study was to compare successful resection rates(RR)with upfront ALPPS vs.PVE with rescue ALPPS on demand and to compare the hypertrophy of the liver between ALPPS and PVE plus subsequent rescue ALPPS.Methods:A retrospective analysis of all patients treated with PVE for colorectal liver metastasis(CRLM)or ALPPS(any diagnosis,rescue ALPPS included)at five Scandinavian university hospitals during the years 2013-2016 was conducted.A Chi-square test and a Mann-Whitney U test were used to assess the difference between the groups.A successful RR was defined as liver resection without a 90-day mortality.Results:A total of 189 patients were included.Successful RR was in 84.5%of the patients with ALPPS upfront and in 73.3%of the patients with PVE and rescue ALPPS on demand(P=0.080).The hypertrophy of the future liver remnants(FLRs)with ALPPS upfront was 71%(48-97%)compared to 96%(82-113%)after PVE and rescue ALPPS(P=0.010).Conclusions:Upfront ALPPS offers a somewhat higher successful RR than PVE with rescue ALPPS on demand.The sequential combination of PVE and ALPPS leads to a higher overall degree of hypertrophy than upfront ALPPS. | Ernesto Sparrelid Kristina Hasselgren Bård Ingvald Røsok Peter Nørgaard Larsen Nicolai Aagaard Schultz Ulrik Carling Eva Fallentin Stefan Gilg Per Sandström Gert Lindell Bergthor Björnsson | 2021 | Hepatobiliary Surgery and Nutrition2021,10,1: | 2 |
| 3 | Isoprene and its degradation products as strong ozone precursors in Insubria, Northern Italy显示文摘 | M Duane B Poma D Rembges C Astorga B.R Larsen | 2002 | Atmospheric Environment2002,,24: | 2 |
| 4 | Quantitative determination of the uronic acid composition of alginates显示文摘 | HANG A LARSEN B | 1962 | Acta Chem Scan1962,16,8: | 1 |
| 5 | Loss-of-function mutations in the ethylene receptor ETR1 cause enhanced sensitivity and exaggerated response to ethylene in Arabidopsis 显示文摘 | Cancel J D Larsen P B | 2002 | Plant Physiology2002,129,: | 1 |
| 6 | Critical chloride content in reinforced concrete-a review显示文摘 | Angst U Elsener B Larsen C K | 2009 | Cement and Concrete Research2009,39,12: | 1 |
| 7 | High dietary calcium level decreases colonic phytate degradation in pigs fed a rapeseed diet显示文摘 | Sandberg A S Larsen T Sandstrom B | 1993 | Journal of Nutrition1993,123,3: | 1 |
| 8 | Priming the cow for mo-bilization in the periparturient period:effects of supplemen-ting the dry cow with saturated fat or linseed显示文摘 | Andersen J B Ridder C Larsen T | 2008 | J Dairy Sci2008,91,3: | 1 |
| 9 | The role of the muhifunctional peptide LL-37 in host defense显示文摘 | Kai Larsen Y Agerberth B | 2008 | Front Bio Sci2008,13,: | 1 |
| 10 | Gangliosides protect bowel in an infant model of necrotizing enterocolitis by suppressing proinflammatory signals 显示文摘 | Schnabl KL Larsen B Van Aerde JE | 2009 | J Pediatr Gas- troenterol Nutr2009,49,4: | 1 |
| 11 | Acute interstitial pneumonia in mink kits inoculated with defined isolates of Aleutian mink disease parvovirus显示文摘 | Alexandersen S Larsen S Aasted B Uttenthal A Bloom M E Hansen M | 1994 | Vet Patho1994,31,2: | 1 |
| 12 | Distribution and petrogenetic behavior of trace elements in granitic pegmatite quartz from South Norway显示文摘 | Larsen R B Henderson I Ihlen P M | 2004 | Contributions to Mineralogy and Petrology2004,147,5: | 1 |
| 13 | 3,4, 5-Trihydrobenzohydroxamic acid monohydrate, a ribonucleotide reductase inhibitor 显示文摘 | Niclsen B B Larsen I K | 1993 | Acta Cryst1993,49,: | 1 |
| 14 | 显示文摘 | Santora B P Larsen A O Gagne M R | 1998 | Organometallics1998,17,15: | 1 |
| 15 | 3-D elastic numerical modeling of a complex salt structure显示文摘 | House L Larsen S Bednar J B | 2000 | SEG Expanded Abstracts2000,19,: | 1 |
| 16 | Effects of temperature on the mussel pump显示文摘 | JOERGENSEN C B LARSEN P S RIISGAARD H U | 1990 | Mar Ecol Prog Ser1990,64,12: | 1 |
| 17 | Counting coccidial oocysts inchicken faeces:a comparative study of a standard McMastertechnique and a new rapid method显示文摘 | Haug A Williams R B Larsen S | 2006 | Veterinary Parasitolo-gy2006,136,34: | 1 |
| 18 | 6 studies of spin-coated polymer films 显示文摘 | Norrman K Ghanbari-Siahkali A Larsen N B | 2005 | Annual Reports Sec- tion C (Physical Chemistry)2005,101,: | 1 |
| 19 | ACE gene polymorphism in cardiovascular disease: meta - analyses of small and large studies in whites 显示文摘 | Agerholm - Larsen B Nordestgaard BG Tybjaerg - Hansen A | 2000 | Arterioscler Thromb Vasc Biol2000,20,2: | 1 |
| 20 | Effect of dietary selenium on the response of stressed and unstressed chickens to Escherichia coli challenge and antigen显示文摘 | Larsen C T Pierson F W Cross W B | 1997 | Biological Trace Elements Research1997,58,3: | 1 |