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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 根治性切缘状态在接受完整结肠系膜切除术治疗的结肠癌患者中的预后价值显示文摘目的:与直肠癌的环周切缘(CRM)相比,根治性切缘(Ra?dial Margin)可能是结肠癌的潜在预后影响因素。目前尚无关于在完整结肠系膜切除术(CME)理念下探索根治性切缘对预后影响的研究。本研究旨在探索在CME治疗结肠癌前提下,根治性切缘状态对肿瘤结局的影响。方法:基于Severance医院的前瞻性结直肠癌登记系统数据,回顾性分析从2010年10月至2013年3月接受根治性切除的Ⅰ~Ⅲ期结肠癌患者资料。共834例接受CME的连续性结肠腺癌患者纳入本研究。根据根治性切缘距离将患者分为3组:A组,根治性切缘≥2 mm;B组,1 mm≤根治性切缘<2 mm;C组,根治性切缘<1 mm。比较各组的总生存期和无病生存期。 | 王枭杰 LEE J M CHUNG T KIM K M | 2020 | 结直肠肛门外科2020，26，2： | 3 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | Screw Dislocation Dipole Near an Internal Crack显示文摘 | Lin K M Hu C T Lee S B | 1993 | Engineering Fracture Mechanics1993，45，： | 1 |
| 5 | Stimulating Fermentative Activities of Bifidobacteria in Milk by High Intensity Ultrasound显示文摘 | NGUYE T M P LEE Y K ZHOU W B | 2009 | International Dairy Journal2009，，19： | 1 |
| 6 | Si-carbon core-shell composite anode in lithium secondary batteries 显示文摘 | JUNG Y S LEE K T OH SEUN M | 2007 | Electrochimica Acta2007，52，： | 1 |
| 7 | Synthesis and properties of semifluorinated block copolymers containing poly(ethylene oxide) and poly(fluorooctyl methacrylates) via atom transfer radical polymerization显示文摘 | Lee M Y Moon M J | 2002 | Polymer2002，43，： | 1 |
| 8 | Application of quasicrystalline particles as a strengthening phase in Mg-Zn-Y alloys 显示文摘 | Bae D H Lee M H Kim K T | 2002 | Journal of Alloys and Com- pouds2002，342，： | 1 |
| 9 | Ultrasonic irradiation for blue-green algae bloom control显示文摘 | LEE T J NAKANO K MATSUMARA M | 2001 | Environ Technol2001，22，4： | 1 |
| 10 | Thermally driven thin film bulk acoustic resonator voltage controlled oscillators integrated with microheater elements 显示文摘 | Lee H M Kim H T Choi H K | 2004 | Jpn J Appl Phys Part2-Lett2004，43，1： | 1 |
| 11 | Measuring and Modeling the Effects of Substrate Noise on the LNA for a CMOS GPS Receiver显示文摘 | Su M Xu D K Shaeffer D K Lee T H | 2001 | IEEE Journal of Solid-State Circuits2001，36，3： | 1 |
| 12 | Synthetic optimization of Li(Ni1/3Co1/3Mn1/3)O2 via co-precipitation显示文摘 | LEE M H KANG Y J MYUNG S T SUN Y K | 2004 | Electrochim Acta2004，50，4： | 1 |
| 13 | Ribozyme-mediated cleavage of the human survivin mRNA and inhibition of antiapoptotic function of survivin in MGF-7 cells 显示文摘 | Choi K S Lee T H Jung M H | 2003 | Cancer Gene Ther2003，10，2： | 1 |
| 14 | Efficient Green Coumarin Dopants for Organic Light-Emitting Devices显示文摘 | Lee M T Yen C K Yang W P | 2004 | Org Lett2004，6，： | 1 |
| 15 | Preparation and properties of nano-silica modified nega- tive acrylate photoresist 显示文摘 | Lee C K Don T M Lai W C Chert C C Lin D J Cheng L P | 2008 | Thin Solid Films2008，516，23： | 1 |
| 16 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013，22，： | 1 |
| 17 | Effects of rainfall events on soil CO2 flux in a cool temperature deciduous broad leaved forest显示文摘 | Lee M S Nakane K Nakatsubo T | 2002 | EcoLogical Research2002，，17： | 1 |
| 18 | Anal Chim Acta显示文摘 | Jing T Xia H Guan Q Lu W H Dai Q Niu J W Lim J M Hao Q L Lee Y Zhou Y K Mei S R | 2011 | 692:732011，692，： | 1 |
| 19 | Design and Implementation of a Dual-stage Actuated HDD Scrvo System via Composite Nonlinear Control Approach显示文摘 | Peng K Chen B M Lee T H | 2004 | Mechatronics2004，14，： | 1 |
| 20 | Stability characteristics of Pt1Ni1/C as cathode catalysts in membrane electrode assembly of polymer electrolyte membrane fuel cell显示文摘 | CHO Y H JEON T Y YOO S J LEE K S AHN M KIM O H CHO Y H LIM J W JUNG N YOON W S CHOE H SUNG Y E | 2012 | Electrochim Acta2012，59，： | 1 |
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