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| 1 | Texture analysis on parametric maps derived from dynamic contrast-enhanced magnetic resonance imaging in head and neck cancer显示文摘AIM: To investigate the merits of texture analysis on parametric maps derived from pharmacokinetic modeling with dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) as imaging biomarkers for the prediction of treatment response in patients with head and neck squamous cell carcinoma(HNSCC). METHODS: In this retrospective study,19 HNSCC patients underwent pre- and intra-treatment DCEMRI scans at a 1.5T MRI scanner. All patients had chemo-radiation treatment. Pharmacokinetic modeling was performed on the acquired DCE-MRI images,generating maps of volume transfer rate(Ktrans) and volume fraction of the extravascular extracellular space(ve). Image texture analysis was then employed on maps of Ktrans and ve,generating two texture measures: Energy(E) and homogeneity.RESULTS: No significant changes were found for the mean and standard deviation for Ktrans and ve between pre- and intra-treatment(P > 0.09). Texture analysis revealed that the imaging biomarker E of ve was significantly higher in intra-treatment scans,relative to pretreatment scans(P < 0.04). CONCLUSION: Chemo-radiation treatment in HNSCC significantly reduces the heterogeneity of tumors. | Jacobus FA Jansen Yonggang Lu Gaorav Gupta Nancy Y Lee Hilda E Stambuk Yousef Mazaheri Joseph O Deasy Amita Shukla-Dave | 2016 | World Journal of Radiology2016，8，1： | 5 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | Antioxidant capacity of phenolic phytochemicals from various cultivars of plums显示文摘 | KIM D O JEONG S W LEE C Y | 2003 | Food Chem2003，81，： | 1 |
| 4 | A Smooth Support Vector Machines显示文摘 | LEE Y J MANGASARIAN O L | 2001 | Comput Optim Appl2001，20，1： | 1 |
| 5 | Isolated middle cerebral artery disease: clinical and neuroradiological features depending on the pathogenesis显示文摘 | Lee P H Oh S H Bang O Y | 2004 | J Neurol Neurosurg Psychiatry2004，75，5： | 1 |
| 6 | In vitro cytotoxicity of tanshinones from salvia miltiorrhiza显示文摘 | Ryu S Y Lee C O Choi S U OL | 1997 | Sang UC Plantan Medicine1997，63，3： | 1 |
| 7 | Characterization of a heat-stable protein with antimicrobial activity from Arabidopsis thaliana显示文摘 | Park S C Lee J R Shin S O Park Y Lee S Y Hahm K S | | 0，，03： | 1 |
| 8 | Monitoring of selected veterinary antibiotics in environmental compartments near a composting facility in Gangwon Province,Korea显示文摘 | Ok Y S Kim S C Kim K R Lee S S Moon D H Lim K J Sung J K Hur S O Yang J E | | 0，，： | 1 |
| 9 | Apreliminary design study for the HYPER system显示文摘 | PARK W S SONG T Y LEE B O | 2002 | Nuclear Engineering and Design2002，219，3： | 1 |
| 10 | Semi-continuous production of tantalum powder by electronically media- ted reaction 显示文摘 | Park H Okabe T H Lee O Y | 2002 | Materials Transactions2002，43，8： | 1 |
| 11 | 显示文摘 | YANG Y O LI C LEE K H CRAIGHEAD H G | 2005 | Electrophoresis2005，26，19： | 1 |
| 12 | Two-sided assembly line balancing to maximize work relatedness and slackness显示文摘 | LEE T O KIM Y KIM Y K | 2001 | Computers & Industrial Engineering2001，40，3： | 1 |
| 13 | Consumption of whole grain and legume powder reduces insulin demand,lipid peroxidation,and plasma homocysteine concentrations in patients with coronary artery disease:randomized controlled clinical trial显示文摘 | Jang Y Lee J H Kim O Y | 2001 | Art Thromb Vasc Biol2001，21，： | 1 |
| 14 | Pattern of expression of cell cycle-related proteins in malignant transformation of sinonasal inverted papilloma 显示文摘 | Kim S G Lee O Y Choi J W | 2011 | Am J Rhinol Allergy2011，25，2： | 1 |
| 15 | Stability characteristics of Pt1Ni1/C as cathode catalysts in membrane electrode assembly of polymer electrolyte membrane fuel cell显示文摘 | CHO Y H JEON T Y YOO S J LEE K S AHN M KIM O H CHO Y H LIM J W JUNG N YOON W S CHOE H SUNG Y E | 2012 | Electrochim Acta2012，59，： | 1 |
| 16 | Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus 显示文摘 | Kim Y O Han S B Lee H W | 2005 | Life Sci2005，77，： | 1 |
| 17 | Structural and mechanistic investigation of a phosphatemodified HZSM-5 catalyst for methanol conversion显示文摘 | Abubakar S M Marcus D M Lee J C Ehresmann J O Chen C Y Kletnieks P W Guenther D R Hayman M J Pavlova M Nicholas J B Haw J F | | 0，，10： | 1 |
| 18 | 显示文摘 | Lee T W Chung Y Kwon O | 2007 | Adv Funct Mater2007，17，3： | 1 |
| 19 | Physical structure and expression of alkBA encoding alkane hydroxy- lase and rubredoxin reductase from Pseudomonas maltophilia 显示文摘 | Lee N R Hwang M O Jung G H Kim Y S Min K H | 1996 | Biochem Biophys Res Commun1996，218，1： | 1 |
| 20 | Characterization of the Streptococcus pneumoniae BgaC protein as a novel surface-gal- actosidase with specific hydrolysis activity for the Gall- 3GlcNAc moiety of oligosaccharides显示文摘 | Jeong J K Kwon O Lee Y M | 2009 | Bacteriol J2009，191，9： | 1 |
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