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| 1 | Gastric cancer: Current status of lymph node dissection显示文摘D2 procedure has been accepted in Far East as the standard treatment for both early(EGC) and advanced gastric cancer(AGC) for many decades. Recently EGC has been successfully treated with endoscopy by endoscopic mucosal resection or endoscopic submucosal dissection, when restricted or extended Gotoda's criteria can be applied and D1+ surgery is offered only to patients not fitted for less invasive treatment. Furthermore, two randomised controlled trials(RCTs) have been demonstrating the non inferiority of minimally invasive technique as compared to standard open surgery for the treatment of early cases and recently the feasibility of adequate D1+ dissection has been demonstrated also for the robot assisted technique. In case of AGC the debate on the extent of nodal dissection has been open for many decades. While D2 gastrectomy was performed as the standard procedure in eastern countries, mostly based on observational and retrospective studies, in the west the Medical Research Council(MRC), Dutch and Italian RCTs have been conducted to show a survival benefit of D2 over D1 with evidence based medicine. Unfortunately both the MRC and the Dutch trials failed to show a survival benefit after the D2 procedure, mostly due to the significant increase of postoperative morbidity and mortality, which was referred to splenopancreatectomy. Only 15 years after the conclusion of its accrual, the Dutch trial could report a significant decrease of recur-rence after D2 procedure. Recently the long term survival analysis of the Italian RCT could demonstrate a benefit for patients with positive nodes treated with D2 gastrectomy without splenopancreatectomy. As nowadays also in western countries D2 procedure can be done safely with pancreas preserving technique and without preventive splenectomy, it has been suggested in several national guidelines as the recommended procedure for patients with AGC. | Maurizio Degiuli Giovanni De Manzoni Alberto Di Leo Domenico D'Ugo Erica Galasso Daniele Marrelli Roberto Petrioli Karol Polom Franco Roviello Francesco Santullo Mario Morino | 2016 | World Journal of Gastroenterology2016，22，10： | 29 |
| 2 | Silicon and silicon nitride photonic circuits for spectroscopic sensing on-a-chip [Invited]显示文摘There is a rapidly growing demand to use silicon and silicon nitride(Si3N4) integrated photonics for sensing applications, ranging from refractive index to spectroscopic sensing. By making use of advanced CMOS technology,complex miniaturized circuits can be easily realized on a large scale and at a low cost covering visible to mid-IR wavelengths. In this paper we present our recent work on the development of silicon and Si3N4-based photonic integrated circuits for various spectroscopic sensing applications. We report our findings on waveguide-based absorption, and Raman and surface enhanced Raman spectroscopy. Finally we report on-chip spectrometers and on-chip broadband light sources covering very near-IR to mid-IR wavelengths to realize fully integrated spectroscopic systems on a chip. | Ananth Z.Subramanian Eva Ryckeboer Ashim Dhakal Frédéric Peyskens Aditya Malik Bart Kuyken Haolan Zhao Shibnath Pathak Alfonso Ruocco Andreas De Groote Pieter Wuytens Daan Martens Francois Leo Weiqiang Xie Utsav Deepak Dave Muhammad Muneeb Pol Van Dorpe Joris Van Campenhout Wim Bogaerts Peter Bienstman Nicolas Le Thomas Dries Van Thourhout Zeger Hens Gunther Roelkens Roel Baets | 2015 | Photonics Research2015，3，5： | 7 |
| 3 | Intestinal permeability test as a predictor of clinical course in Crohn’s disease显示文摘 | Renata D’Incà Vincenza Di Leo Giovanni Corrao Diego Martines Anna D’Odorico Cinzia Mestriner Carla Venturi Giuseppe Longo Giacomo Carlo Sturniolo | 1999 | The American Journal of Gastroenterology1999，，： | 2 |
| 4 | Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease显示文摘 | Renata D’Incà Elisabetta Pont Vincenza Leo Antonio Ferronato Walter Fries Maria Grazia Vettorato Diego Martines Giacomo Carlo Sturniolo | 2007 | International Journal of Colorectal Disease2007，，4： | 2 |
| 5 | Partition coefficients and their uses显示文摘 | LEO A HANSCHA C ELKINS D | 1971 | Chem Rev1971，71，6： | 1 |
| 6 | HER-2 amplification and topoisomerase 11 alpha gene aberration as predictive markers in node - positive breast cancer patients randomly treated either withan anthracycline - based therapy or with eyclophosphamide, methotrexate, and 5 - fluorouracil显示文摘 | Di Leo A Gabcberg D Larsimont D | 2002 | Clinical Cancer Res2002，8，： | 1 |
| 7 | Increased uncouplingprotein-2 levels inβ-cells are associated with impaired glucose-stimulated insulin secretion:mechanism of action显示文摘 | Chan CB De Leo D Joseph JW | 2001 | Diabetes2001，50，： | 1 |
| 8 | Functional consequences of alterations to polar amino acids located in the transmembrane domain of the Ca^2+ -ATPase of sareoplasmic reticulum 显示文摘 | Clark M Leo T W Maelerman D H | 1990 | J Biochem1990，265，11： | 1 |
| 9 | An outlook on ovarian cancer and borderline ovarian tumors:focus on genomic and proteomic findings显示文摘 | Tinelli A Vergara D Martignago R Leo G Pisanò M Malvasi A | | 0，，： | 1 |
| 10 | 查看详情显示文摘 | Tol′edano P Leo N Khalyavin D D | | 0，，： | 1 |
| 11 | Treatment outcome of mineral trioxide aggregate: repair of root perforations-long-term results 显示文摘 | Mente J Leo M Panagidis D | 2014 | J Endod2014，40，6： | 1 |
| 12 | HER-2 and topoi- somerase llalpha as predictive cancer patients randomly treated with adjuvant CMF or epirubicin plus cyelophosphamide显示文摘 | Di Leo A Larsimont D Gabcberg D | 2001 | Ann Oncol2001，12，： | 1 |
| 13 | HER-2 and topo-isomerase IIalpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide显示文摘 | Leo AD Larsimont D Gancberg D | 2001 | Ann Oncol2001，12，： | 1 |
| 14 | A new algorithm for ball recognition using circle Hough transform and neural classifier显示文摘 | 'ORAZIO T D GUARAGNELLA C LEO M | 2004 | Pattern Recognition2004，37，： | 1 |
| 15 | Field study of the flow behind single and double row herbaceous windbreaks显示文摘 | Boldes U Colman J Leo J M D | 2001 | Journal of Wind Engineering and Industrial Aerodynamics2001，89，： | 1 |
| 16 | Treatment outcome of mineral trioxide aggregate in open apex teeth 显示文摘 | Mente J Leo M Panagidis D | 2013 | J Endod2013，39，1： | 1 |
| 17 | Functional anatomy of the Eustachian tube显示文摘 | Cunsolo E Marchioni D Leo G | 2010 | Int J Immunopathol Pharmacol2010，23，1： | 1 |
| 18 | Chromogenic in situ hy-bridization : a practical alternative for fluorescence in situ hybridiza- tion to detect HER-2/neu oncogene amplification in archival breast cancer samples 显示文摘 | Tanner M Gancberg D Di Leo A | 2000 | Am J Pathol2000，157，5： | 1 |
| 19 | Triterpenoids saponins from Pteleopsis suberosa stem bark 显示文摘 | Leo M D Tommasi N D Sanogo R | 2006 | Phytochemistry2006，67，： | 1 |
| 20 | Platelet activation by superoxide anion and hydroxyl radicals intrinsically generated by platelets that had undergone anoxia and than reoxygenated显示文摘 | Leo R Pratico D Iuliano L | 1997 | Circulation1997，95，4： | 1 |
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