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| 1 | Breath test for differential diagnosis between small intestinal bacterial overgrowth and irritable bowel disease:An observation on non-absorbable antibiotics显示文摘AIM: To estimate the prevalence of small intestine bacterial overgrowth (SIBO) among patients with an earlier diagnosis of irritable bowel disease (IBS) in our geographical area, and to collect information on the use of locally acting non-absorbable antibiotics in the management of SIBO. METHODS: A non-interventional study was conducted in 73 consecutive patients with a symptom-based diagnosis.. RESULTS: When the patients underwent a 'breath test', 33 (45.2%) showed the presence of a SIBO. After treatment with rifaximin 1200 mg/d for seven days in 32 patients, 19 (59.4%) showed a negative 'breath test' one week later as well as a significant reduction of symptoms, thus confirming the relationship between SIBO and many of the symptoms claimed by patients. In the other 13 patients, 'breath test' remained positive, and a further cycle of treatment with ciprofloxacin 500 mg/d was given for 7 additional days, resulting in a negative 'breath test' in one patient only. CONCLUSION: (1) about half of the patients with a symptomatic diagnosis of IBS have actually SIBO, which is responsible for most of the symptoms attributed to IBS; (2) only a 'breath test' with lactulose (or with glucose in subjects with an intolerance to lactose) can provide a differential diagnosis between IBS and SIBO, with almost identical symptoms; and (3) the use of non-absorbable antibiotics may be useful to reduce the degree of SIBO and related symptoms; it must be accompanied, however, by the correction of the wrong alimentary habits underlying SIBO. | I Esposito A de Leone G Di Gregorio S Giaquinto L de Magistris A Ferrieri G Riegler | 2007 | World Journal of Gastroenterology2007，13，45： | 8 |
| 2 | The age of multilevel converters arrives显示文摘 | L G Franquelo J Rodriguez J I Leon S Kouro R Portillo and M A M Prats | | 0，，02： | 1 |
| 3 | Reduced sensorimotor inhibition in the ipsilesional motor cortex in a patient with chronic stroke of the paramedian thalamus显示文摘 | Oliviero A Leon AM Holier I | 2005 | Clin Neurophysiol2005，116，11： | 1 |
| 4 | Power-electronic systems for the grid integration of renewable energy sources: A survey 显示文摘 | CARRASCO J M FRANQUELO L G BIALASIEWICZ J T GALVAN E GUISADO R C P PRATS M A M LEON J I MORENO N | 2006 | IEEE Transactions on Industrial Electronics2006，53，4： | 1 |
| 5 | Conventional space-vector modulation techniques versus the single-phase modulator for multilevel converters显示文摘 | Leon J Vazquez I S Sanchez J A | 2010 | IEEE Trans on Industrial Electronics2010，57，7： | 1 |
| 6 | Efficacy results of a trial of a herpes simplex vaccine显示文摘 | BELSHE R B LEONE P A BERNSTEIN D I | 2012 | N Engl J Med2012，366，1： | 1 |
| 7 | Feed-forward space vector modulation for single-phasemultilevel cascaded converters with any DC voltageratio 显示文摘 | LEON J I VAZQUEZ S WATSON A } | 2009 | IEEE Transactions on IndustrialElectronics2009，56，2： | 1 |
| 8 | Modification of the surface properties of an activated carbon by oxygen plasma treatment显示文摘 | GARC(I)A Ana MART(I)NEZ-ALONSO Amelia LEON Carlos Leon Y | 1998 | Fuel1998，77，6： | 1 |
| 9 | The Transparent TESTA12 gene of Arabidopsis Encodes a Multidrug Secondary Transporter-like Protein Required for Flavonoid Sequestration in Vacuoles of the Seed Coat Endothelium 显示文摘 | DEBEAUJON I PEETERS A J LEON K M | 2001 | Plant Cell2001，13，4： | 1 |
| 10 | Design and testing of an efficient and compact piezoelectric energy harvester显示文摘 | KORLA S LEON R A TANSEL I N | 2011 | Microelectronics Journal2011，42，2： | 1 |
| 11 | Control strategy for hard- ware simplification of voltage source converter-based power applica- tions显示文摘 | LEON A E SOLSONA J A VALLA M I | 2011 | Power Electronics: lET2011，4，1： | 1 |
| 12 | Chronic intake of caffeine during gestation down regulates metabotropic glutamate receptors in maternal and fetal rat heart 显示文摘 | Iglesias I Leon D Ruiz M A | 2006 | Amino Acids2006，30，3： | 1 |
| 13 | Fluorine Toxicitity in Tomato as Modified by Alteration in the Nitrogen, Calcium and Phosphorus Nutrition of the plant 显示文摘 | Brennan E G Leone I A Daines R H | 1950 | Plant Physiol1950，25，： | 1 |
| 14 | Involvement of the Arabidopsisalpha-DOX1 fatty acid dioxygenase in protection against oxidativestress and cell death显示文摘 | Ponce de Leon I Sanz A Hamberg M | 2002 | The Plant Journal2002，29，1： | 1 |
| 15 | Cxc chemokines connective-tissue activating peptide-iii and neutrophil-activating peptide-2 are heparin heparan sulfate- degrading enzymes 显示文摘 | HOOGEWERF A J LEONE J W REARDON I M | 1995 | J Biol Chem1995，270，7： | 1 |
| 16 | New UV-curable high refractive index oligomers显示文摘 | NEBIOGLU A LEON J A KHUDYAKOV I V | 2008 | Industrial & Engineering Chemistry Research2008，47，7： | 1 |
| 17 | Feed- forward space vector modulation for single-phase multi- level cascaded converters with any DC voltage ratio 显示文摘 | LEON J I VZAQUEZ S WATSON A J | 2009 | IEEE Trans Ind Electron2009，56，2： | 1 |
| 18 | Efficacy results of a trial of a herpes simplex vaccine显示文摘 | BELSHE R B LEONE P A BERNSTEIN D I | 2012 | N Engl J Med2012，366，1： | 1 |
| 19 | The response oftomato plants to simulated landfill gas mixtures显示文摘 | Arthur J J Leone I A Flower F B | 1985 | Journal of Environmental Science and Health1985，20，8： | 1 |
| 20 | Perceptions of group and personal influences and effectiveness among disabled and able-bodied members of a Russian wheelchair expedition显示文摘 | Leon G R Fulkerson J A Luepker I R | 1997 | International Journal of Sport Psychology1997，28，： | 1 |
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