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241篇 您的检索式：作者名="LEONG C M"

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	题名	作者	年代	出处	被引量
1	miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus显示文摘AIM: To investigate miR-200 family expression in Barrett's epithelium, gastric and duodenal epithelia, and esophageal adenocarcinoma. METHODS: Real-time reverse transcriptase-polymerase chain reaction was used to measure miR-200, ZEB1 and ZEB2 expression. Ingenuity Pathway Analysis of miR-200 targets was used to predict biological outcomes. RESULTS: Barrett's epithelium expressed lower levels of miR-141 and miR-200c than did gastric and duodenal epithelia (P < 0.001). In silico analysis indicated roles for the miR-200 family in molecular pathways that distinguish Barrett's epithelium from gastric and duodenalepithelia, and which control apoptosis and proliferation. All miR-200 members were downregulated in adenocarcinoma (P < 0.02), and miR-200c expression was also downregulated in non-invasive epithelium adjacent to adenocarcinoma (P < 0.02). The expression of all miR-200 members was lower in Barrett's epithelium derived high-grade dysplastic cell lines than in a cell line derived from benign Barrett's epithelium. We observed signif icant inverse correlations between miR-200 family expression and ZEB1 and ZEB2 expression in Barrett's epithelium and esophageal adenocarcinoma (P < 0.05). CONCLUSION: miR-200 expression might contribute to the anti-apoptotic and proliferative phenotype of Barrett's epithelium and regulate key neoplastic processes in this epithelium.	Cameron M Smith David I Watson Mary P Leong George C Mayne Michael Z Michael Bas PL Wijnhoven Damian J Hussey	2011	World Journal of Gastroenterology2011，17，8：	13
2	Application of flexible printed circuit board (FPCB) in personal computer motherboards: Focusing on mechanical performance 显示文摘	LEONG W ABDULLAH M KHOR C	2012	Microelectronics Reliability2012，52，4：	1
3	Infiltration effects on stability of a residual soil slope显示文摘	GASMO J M RAHARDJO H LEONG E C	2000	Computers and Geotechnics2000，26，2：	1
4	Depletion of langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin显示文摘	MATTHEWS K LEONG C M BAXTER L	2003	J Virol2003，77，：	1
5	Infiltration Effects on Stability of a Residual Soil Slope显示文摘	Gasmo J M Rahardjo H Leong E C	2000	Computers and Geote Chanics2000，26，2：	1
6	Infiltration effects on stability of a residual soil slope显示文摘	CASMO J M RAHARDJO H LEONG E C	2000	Computers & Geotechnics2000，26，：	1
7	Elastoplastic model for unsaturated soil with incorporation of the soil-water characteristic curve 显示文摘	THU T M RAHARDJO H LEONG E C	2007	Canadian Geotechnicai Journal2007，44，1：	1
8	Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs 显示文摘	K F Leong C M Cheah C K Chua	2003	Biomaterials2003，24，：	1
9	Infiltration effects on stability of a residual soil slope显示文摘	GASMO J M RAHARDJO H LEONG E C	2000	Computers and Geotechnics2000，26，2：	1
10	One-dimensional analysis of soil plugs in pipe piles显示文摘	RANDOLPH M F LEONG E C HOULSBY G T	1991	Geotechnique1991，41，4：	1
11	Infiltration effects on stability of a residual soil slope 显示文摘	GASMO J M RAHARDJO H LEONG K C	2000	Computers and Geoteehnies2000，26，2：	1
12	The p63/p73 network mediates chemosensitivity tocisplatin in a biologically defined subset of primarybreast cancers 显示文摘	LEONG C 0 VIDNONIC N DEYOUNG M P	2007	J Clin Invest2007，117，5：	1
13	Critical statebehaviour of a compacted silt specimen显示文摘	THU T M RAHARDJO H LEONG E C	2007	Soils&Foundations2007，47，：	1
14	An experimental study of cavitation detection in a centrifugal pump using envelope analysis 显示文摘	Tan C Z Leong M S	2008	Journal of System Design and Dynamics2008，2，1：	1
15	Enhanced thermal conductivity of TiO2-water based nanofluids 显示文摘	Murshed S M S Leong K C Yang C	2005	International Journal of Thermal Sciences2005，44，4：	1
16	Inherent safety index module (ISIM) to assess inherent safety level during preliminary design stage显示文摘	Leong C T Shariff A M	2008	Process Safety and Environmental Protection2008，86，2：	1
17	Perceptions of Macao NurseAdministrators on the Core Competencies of Registered Nurse显示文摘	Liu M Yin L Leong C	2007	J Macao Polytechnic Institute2007，，1：	1
18	Infiltration effects on stability of a residual soil slope显示文摘	Gasmo J M Tahardjo H Leong E C	2000	Computers and Geotechnics2000，26，2：	1
19	Process route index (PRI) to assess level of explosiveness for inherent safety quantification显示文摘	Leong C T Sbariff A M	2009	Journal of Loss Prevention in the Process Industries2009，22，2：	1
20	Enhanced thermal con- ductivity of TiO2-water based nanofluids 显示文摘	MURSHED S M LEONG K C YANG C	2005	International Journal of Thermal Sciences2005，44，6：	1

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