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| 1 | Serum cytokine profile in patients with hepatitis B e antigen-negative chronic active hepatitis B and inactive hepatitis B virus carriers显示文摘An insufficient cellular immune response seems to be critical for the immunopathogenesis of chronic hepatitis B virus infection.We have previously demonstrated no differences of T-lymphocyte subsets in blood between inactive hepatitis B s antigen(HBsAg) carriers and patients with HBeAg-negative chronic active hepatitis B.This study investigated the peripheral blood cytokine profile in patients with HBeAg-negative chronic active hepatitis B infection(Group A,n = 21) and inactive HBsAg carriers(Group B,n = 13).Serum cytokines [interferon(IFN)-γ,tumor necrosis factor-α,interleukin(IL)-1b,IL-4,IL-12,IL-10,IL-2,IL-5,IL-8] were analyzed by using flow cytometry.Patients with chronic active disease presented with significantly decreased levels of IFN-γ and IL-10 compared to inac-tive carriers(P = 0.048 and P = 0.008,respectively).In HBeAg-negative chronic active hepatitis B patients,a significant negative correlation of IFN-γ levels with serum hepatitis B viral load was noted(P = 0.021).In conclusion,patients with HBeAg-negative chronic active hepatitis B and HBsAg inactive carriers display a different cytokine profile.Decreased Th1 response observed in patients with chronic active hepatitis B could be implicated in the persistence of virus replication and ongoing progression of liver disease. | Dimitra Dimitropoulou Marina Karakantza Georgios L Theodorou Lydia Leonidou Stelios F Assimakopoulos Athanasia Mouzaki Charalambos A Gogos | 2013 | World Journal of Gastrointestinal Pathophysiology2013，4，1： | 13 |
| 2 | Cytoldne produc- tion and hospital mortality in patients with sepsis-induced stress hyperglycemia显示文摘 | Leonidou L Mouzaki A Michalaki M | 2007 | Infection2007，55，4： | 1 |
| 3 | Exercised power as a driver of trust and commitment in cross- border industrial buyer-seller relationships 显示文摘 | Leonidou L C Talias M A Leonidou C N | 2008 | In- dustrial Marketing Management2008，37，1： | 1 |
| 4 | Cytokine production and hospital mortality in patients with sepsis-induced stress hyperglycemia显示文摘 | LEONIDOU L MOUZAKI A MICHAI AKI M | 2007 | J Infect2007，55，4： | 1 |
| 5 | Stress-induced hy- perglycemia in patients with severe sepsis a compromising factor for survival显示文摘 | Leonidou L Michalaki M Leonardou A | 2008 | Am J Med Sci2008，336，6： | 1 |
| 6 | Standarzation versus adaptation of international marketing strategy: an integrative assessment of the empirical research 显示文摘 | Theodosiou M Leonidou L C | 2003 | International Re- view2003，12，2： | 1 |
| 7 | Standardization versus adaptation of international marketing strategy:an integrative assessment of the empirical research显示文摘 | Theodosiou M Leonidou L C | 2003 | International Business Review2003，12，： | 1 |
| 8 | Stress- induced hyperglycemia in patients with severe sepsis: a compromising factor for survival显示文摘 | Leonidou L Michalaki M Leonardou A | 2008 | Am J Med Sci2008，336，6： | 1 |
| 9 | Opportunism as the inhibiting trigger for develo- ping long-term-oriented western exporter Hong Kong importer relationships 显示文摘 | Barnes B R Leonidou L C Siu N Y M Leonidou C N | 2010 | Journal of International Marketing2010，18，2： | 1 |
| 10 | Cytokinc production and hospital mor- tality in patients with sepsis-induced stress hyperglycemia 显示文摘 | Leonidou L Mouzaki A Michalaki M DeLastie AL Kyriazopou- lou V Bassaris HP | 2007 | J Infect2007，55，： | 1 |
| 11 | Adrenomedullin and the microvasculature显示文摘 | Leonid L Nikitenko David M | 2002 | Pharmacological Sciences2002，23，3： | 1 |
| 12 | XML Data Exchange : Consistency and Query Answering显示文摘 | Marcelo A Leonid L | 2008 | Journal of the ACM2008，55，2： | 1 |
| 13 | Lubricant replenishment in rolling bearing contacts显示文摘 | Leonid G Mats G L Piet M L | 2008 | STLE Trans2008，51，： | 1 |
| 14 | Export stimulation research: Review,evaluation and integration显示文摘 | Leonidou L C | 1995 | International Business Re- view1995，4，2： | 1 |
| 15 | Marketing strategy determinants of export performance: a meta-analysis 显示文摘 | Leonidou L C Katsikeas C S Samieec S | 2002 | Journal of Business Research2002，，55： | 1 |
| 16 | Analytic model of the Griineisen parameter all densities显示文摘 | Leonid Burakovsky Dean L Preston | 2004 | J Phys Chem Sol2004，65，89： | 1 |
| 17 | Features of reaction amino- cyclocarboante for production of new type nonisocyanate polyurethane coating显示文摘 | Oleg L Figovsky O L Leonid D | 2002 | Macromol Syrup2002，187，： | 1 |
| 18 | Business unethicality as an impediment to consumer trust:The moderating role of demographic and cul- tural characteristics显示文摘 | Leonidou L | 2013 | Journal of Business Ethics2013，112，3： | 1 |
| 19 | Na- tional expert-promotion programs as drivers of organi- zatidnal resources and capabilities:Effects on strate- gy, competitive advantage, and performance 显示文摘 | Leonidou L C Palihawadana S Theodosiou M | 2011 | Journal of International Marketing2011，19，2： | 1 |
| 20 | Stress-induced hypergly- cemia in patientswith severe sepsis:a compromising factor for survival 显示文摘 | Leonidou L Miehalaki M Leonardou A | 2008 | Am JMecl Sci2008，336，6： | 1 |
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