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| 1 | Predictive factors for compliance with transanal irrigation for the treatment of defecation disorders显示文摘AIM To investigate compliance with transanal irrigation(TAI) one year after a training session and to identify predictive factors for compliance.METHODS The compliance of one hundred eight patients [87 women and 21 men; median age 55 years(range 18-83)] suffering from constipation or fecal incontinence(FI) was retrospectively assessed. The patients were trained in TAI over a four-year period at a single institution. They were classified as adopters if they continued using TAI for at least one year after beginning the treatment or as non-adopters if they stopped. Predictive factors of compliance with TAI were based on pretreatment assessments and trainingprogress. The outcomes of the entire cohort of patients who had been recruited for the TAI treatment were expressed in terms of intention-to-treat.RESULTS Forty-six of the 108(43%) trained patients continued to use TAI one year after their training session. The patients with FI had the best results, with 54.5% remaining compliant with TAI. Only one-third of the patients who complained of slow transit constipation or obstructed defecation syndrome continued TAI. There was an overall discontinuation rate of 57%. The most common reason for discontinuing TAI was the lack of efficacy(41%). However, 36% of the patients who discontinued TAI gave reasons independent of the efficacy of the treatment such as technical problems(catheter expulsion, rectal balloon bursting, instilled water leakage or retention, pain during irrigation, anal bleeding, anal fissure) while 23% said that there were too many constraints. Of the patients who reported discontinuing TAI, the only predictive factor was the progress of the training(OR = 4.9, 1.3-18.9, P = 0.02).CONCLUSION The progress of the training session was the only factor that predicted patient compliance with TAI. | Clémence Bildstein ChloéMelchior Guillaume Gourcerol Estelle Boueyre Valérie Bridoux Eric Vérin Anne-Marie Leroi | 2017 | World Journal of Gastroenterology2017，23，11： | 3 |
| 2 | Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis显示文摘 | Robin MA LeRoy M Descatoire V | 1997 | J Hepatol1997，26，1： | 1 |
| 3 | Antiproliferative effect of semaphorin 3Fon human melanoma cell lines显示文摘 | Chabbert-de Ponnat I Buffard V Leroy K | 2006 | J Invest Dermatol2006，126，10： | 1 |
| 4 | Role of manganese superoxide dismutase on growth and invasive properties of human estrogen- independent breast cancer cells显示文摘 | Kattan Z Minig V Leroy P | 2008 | Breast Cancer Res Treat2008，108，20： | 1 |
| 5 | The use of a fluorescent dye,Nile red,to evaluate the lipid content of single mammalian oocytes显示文摘 | Genicot G Leroy J L Soom A V | 2005 | Theriogenology2005，63，4： | 1 |
| 6 | Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing mother-to-child transmission of HIV in Africa?显示文摘 | Leroy V Sakarovitch C Cortina-Borja M | 2005 | AIDS2005，19，16： | 1 |
| 7 | Meta-analys is of interferon randomized trials in the treatment of viral hepatitis C B effects of do and duration显示文摘 | Poynard T Leroy V Cohard M | 1996 | Hepatology1996，24，： | 1 |
| 8 | Carer burden in apathy and impulse control disorders in Parkinson' s disease显示文摘 | Leroi I Harbishettar V Andrews M | 2012 | Int J Geriatr Psychiatry2012，27，： | 1 |
| 9 | Prediction of mod- erate and high grade vesicoureteral reflux after a first febrile urinary tract infection in children:Construction and internal validation of a clinical decision rule显示文摘 | Leroy S Romanello C Smolkin V | 2012 | The Jour- nal of Urology2012，187，1： | 1 |
| 10 | The use of a fluorescent dye, nile red, to evaluate the lipid content of single mammalian oocytes 显示文摘 | Genicot G Leroy J L Soom A V | 2005 | Theriogenology2005，63，4： | 1 |
| 11 | Human Ebola outbreak resulting from direct exposure to fruit bats in Luebo,Democratic Republic of Congo,2007显示文摘 | Leroy E M Epelboin A Mondonge V | 2009 | Vector-Borne and Zoonotic Diseases2009，9，： | 1 |
| 12 | The genome of cyprinid herpesvirus 3 encodes 40 proteins incorporated in mature virions显示文摘 | Michel B Leroy B Stalin V | 2010 | J Gen Virol2010，91，2： | 1 |
| 13 | Study of simple sequence repeat (SSR) markers from wheat expressed sequence tags (ESTs) 显示文摘 | NICOT N CHIQUET V GANDON B AMILHAT L LEGEAI F LEROY P BERNARD M SOURDILLE P | 2004 | Theor Appl Genet2004，109，： | 1 |
| 14 | Apoptosis in cumulus cells,but not in oocytes,may influence bovine embryonic developmental competence显示文摘 | Yuan Y Q Soom A V Leroy J L M R | 2005 | Theriogenology2005，63，： | 1 |
| 15 | Low birthweight in inrants born to African HIV - infected women: relationship with maternal body weight during pregnancy: Pregnancy and HIV Study Group ( EGE ) 显示文摘 | Castetbon K Ladner J Leroy V | 2001 | J Trop Pediatr2001，45，： | 1 |
| 16 | Acute urine retention: a rare mode of revelation of cervico-dorsal syringomyelia caused by cyproheptadine显示文摘 | Leroy B Forin V | 1994 | Arch Pediatr1994，，3： | 1 |
| 17 | 显示文摘 | Leroy V | 1998 | Lancet1998，352，9128： | 1 |
| 18 | Circulating matrix metalloProteinases 1,2,9 and their inhibitors TIMP-1 and TTMP-2 as serum markers of liver fibrosis in patients with chronic hepatitis C:comparison with PIIINP and hyaluronic acid显示文摘 | LEROY V MONIER F BOTTARI S | 2004 | Am J Gastroenterol2004，99，： | 1 |
| 19 | Plasma membrane cytochromes P450 as neoantigens and autoimmune target s in drug-induced hepatitis显示文摘 | Robin MA LeRoy M Descatoire V | 1997 | J Hepatol1997，26，： | 1 |
| 20 | A Principal- Agent Model for Product Specification and Production显示文摘 | Ananth V Iyer Leroy B Sehwarz Stefanos A Zenios | 2005 | Management Science2005，51，1： | 1 |
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