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| 1 | Inhibition of Herpes Simplex Virus-1 Replication by Natural Compound Honokiol显示文摘Honokiol is a pleiotropic natural compound isolated from Magnolia and has multiple biological and clinically relevant effects,including anticancer and antimicrobial function.However,the antiviral activity of honokiol has not yet been well studied.Here we showed that honokiol had no effect on herpes simplex virus-1(HSV-1)entry,but inhibited HSV-1 viral DNA replication,gene expression and the production of new progeny viruses.The combination of honokiol and clinical drug acyclovir augmented inhibition of HSV-1 infection.Our results illustrate that honokiol could be a potential new candidate for clinical consideration in the treatment of HSV-1 infection alone or combination with other therapeutics. | Shuai Liu Long Li Lingbing Tan Xiaozhen Liang | 2019 | Virologica Sinica2019，34，3： | 4 |
| 2 | Studies on the poly(lactic-co-glycolic) acid microspheres of cisplatin for lungtargeting显示文摘 | Huo Dongjie Deng Shuhai Li Lingbing | 2005 | International Journal of Pharmaceutics2005，289，12： | 1 |
| 3 | Sol-gel Glass-coated Zinc Oxide for Varistor Applications显示文摘 | Lingbing Kong Fengchun Li Liangying Zhang Xi Yao | 1998 | Journal of Materials Science Letters1998，，9： | 1 |
| 4 | Preparation and properties of hydroxycamptothecin-loaded nanoparticles made of amphiphilic copolymer and normal polymer显示文摘 | Wang Jinli Wang Rong Li Lingbing | 2009 | Colloid and Interface Science2009，336，2： | 1 |
| 5 | Germ cell sex prior to meiosis in the rainbow trout显示文摘Germ cells make two major decisions when they move from an indeterminate state to their final stage of gamete production.One decision is sexual commitment for sperm or egg production,and the other is to maintain mitotic division or entry into meiosis.It is unclear whether the two decisions are made as a single event or separate events,because there has been no evidence for the presence of germ cell sex prior to meiosis.Here we report direct evidence in the fish rainbow trout that gonia have distinct sexuality.We show that dazl expression occurs in both male and female gonia but exhibits differential intracellular distribution.More strikingly,we show that boule is highly expressed in male gonia but absent in female gonia.Therefore,mitotic gonia possess sex,sperm/egg decision and mitosis/meiosis decision are two independent events,and sperm/egg decision precedes mitosis/meiosis decision in rainbow trout,making this organism a unique vertebrate model for mechanistic understanding of germ cell sex differentiation and relationship between the two decisions. | Mingyou Li Qian Shen Foong Mei Wong Hongyan Xu Ni Hong Lingbing Zeng Lin Liu Qiwei Wei Yunhan Hong | 2011 | Protein & Cell2011，2，1： | 1 |
| 6 | Curcumin-loaded PLGA-PEG-PLGA triblock copolymeric micelles: Preparation, pharmacokinetics and distribution in vivo显示文摘 | Zhimei Song Runliang Feng Min Sun Chenyu Guo Yan Gao Lingbing Li Guangxi Zhai | 2010 | Journal of Colloid And Interface Science2010，，1： | 1 |
| 7 | Genetic and molecular biological characterization of two homologous cheR genes from Leptospira interrogans显示文摘螺旋体 interrogans 染色体编码 cheR 基因的二个拷贝,他们中的每能为 Escherichia coli cheR 0 异种 RP1254 的聚集的有缺点的显型补充到某些程度,当他们的也的在表示上禁止趋化性的野类型的 E 聚集时。coli 紧张, RP437。因此, CheR1 和 CheR2 应该忍受 methyltransferase 活动,尽管 CheR1 有仅仅而不是位于 2 螺旋的断然控告的脸的二保存基本氨基酸残余。当象 CheR2 的 Lys48 和 Arg55 一样的这残余被变异时,任何一个 CheRs 都不能维持上述的互补功能,建议他们考虑到类似于 E 的接受甲基的趋化性蛋白质的关键角色。coli。由 microarray 试金示威了,在 L 的 cheR1 的表情。在 28 点有教养的 | Yunyi Zhang Ke Dong Lingbing Zeng Qingtian Li Chang Liu Jin Wang Xiaokui Guo Guo-Ping Zhao | 2013 | Acta Biochimica et Biophysica Sinica2013，45，10： | 1 |
| 8 | Studies on the poly (lactic-co-glycolic)acid microspheres of cisplatin for lungtargeting 显示文摘 | HUO DONGJIE DENG SHUHAI LI LINGBING | 2005 | International Jo-urnal of Pharmaceutics2005，289，12： | 1 |
| 9 | Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles显示文摘 | HouLi Li XiaoBin Zhao YuKun Ma GuangXi Zhai LingBing Li HongXiang Lou | 2008 | Journal of Controlled Release2008，，3： | 1 |
| 10 | Enhancement on oral absorption of paclitaxel by multifunctional pluronic micelles显示文摘 | Yimu Li Yiling Bi Yanwei Xi Lingbing Li | 2013 | Journal of Drug Targeting2013，，2： | 1 |
| 11 | Enhancement on oral absorption of paclitaxel by multifunctional pluronic micelles显示文摘 | Yimu Li Yiling Bi Yanwei Xi Lingbing Li | 2013 | Journal of Drug Targeting2013，，2： | 1 |
| 12 | Silicon quantum-wires arrays synthesized by chemical vapor deposition and its micro-structural properties 显示文摘 | LU Mei LI Mengke KONG Lingbing | 2003 | Chem Phys Lett2003，374，5： | 1 |
| 13 | Persistent Spectral Hole Burning of Eu^3+ Doped Y2SiO5 Crystal at 579.62 nm显示文摘 | Xue Shaolin Chen Lingbing Zhao Youyuan Li Fuming Zhang Shoudu Huang Haobing | 2006 | Journal of Rare Earths2006，24，4： | 0 |
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