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3篇 您的检索式:作者名="LIU Xingdang"
    题名 作者 年代 出处 被引量
1Chinese SPECT semi-quantitative analysis of striatum显示文摘To study and analyze reconstruction parameters in 99mTc-Trodat-l SPECT(Tomography EmissionComputed Single-Photon) brain semi-quantitative analysis,and the outlined methods of ROIs(regions of interests). The 99mTc-trodat-l SPECT brain imaging was processed,and the ROIs were outlined four times from December 2009 to July 2011.The results for each method were analyzed and compared to improve our experience.There was no statistically significance between the outlined number of pixel in both sides of the cerebellum and the ratio of the radioactive counts.From LEHR and FAN beam collimator,the average ratio became better with increasing the outlining method,especially the fourth time.It could be estimated that striatum mean volume(±SD) was(39.51±9.54 ml,in the range of 19.97-51.98 mL) and mean weight(±SD) was(44.09±10.64 g in the range of 22.28-58.01 g).The details of image processing and data analysis should not be ignored to outline appropriate methods,and withstand the repetitive inspection.The total striatum was outlined and its volume and weight was analyzed.WANG Yuankai LIU Xingdang ZUO Chuantao LIU Congjin LIU Miao ZHANG Guangming CHEN Zhengping TANG Jie 2012Nuclear Science and Techniques2012,23,6:0
2Comparable investigation in dopamine transporters with ^(99m)Tc-TRODAT-1 and ^(131)I-FP-CIT SPECT in Parkinson's disease patients显示文摘Dopamine transporter (DAT) mediates the regulation of dopaminergic function. Two agents of TRODAT-1 and FP-CIT were observed in evaluating DAT change of Parkinson's disease (PD). The relationship between them was also evaluated. The results suggested that 99mTc-TRODAT-1 SPECT and 131I-FP-CIT SPECT may serve as sensitive and objective in vivo markers to reflect the severity of PD. The 99mTc-TRODAT-1 image is more accurate and clearer compared with 131I-FP-CIT.LIU Congjin LIU Xingdang ZHANG Guangming LI Ding WANG Jian YANG Liqin JIANG Yuping 2007Nuclear Science and Techniques2007,18,4:0
3Feasibility of ^(99m)Tc-TRODAT-1 Micro-SPECT imaging of dopamine transporter in animal retinas显示文摘In this paper,^(99m)Tc-TRODAT-1 Micro-SPECT (single-photon emission computed tomography) was used for imaging dopamine transporter (DAT) in retinas and to investigate the changes of DAT in retinas of guinea pigs with form deprivation myopia.Pigmented guinea pigs aged 3 weeks were derided into form deprivation myopia (FDM) group (n=6) and normal control group (n=6).The test group wore translucent goggles randomly for 4 weeks, and both groups underwent biometric measurement (refraction and axial length) before and after the experiment. Micro-SPECT retinas imaging was performed at the 4^(th) week after injection of ^(99m)Tc-TRODAT-1.The retinas were clearly resolved in the images.The ratio of ^(99m)Tc-TRODAT-1 uptake in the myopic retinas (11.55±2.80) was 3.64±1.40 lower than that in the control eye (15.20±1.98),and 2.35±1.05 lower than that in the fellow eyes (13.90±2.04).The results showed that ^(99m)Tc-TRODAT-1 Micro-SPECT eye imaging can be used to trace the distribution and changes of DAT in retina,and DAT in the myopic retinas were lower than that in the normal control eyes and fellow eyes.Micro-SPECT may provide a new approach for further studies on the role of dopamine system in the experimental myopia.ZHAO Juan QI Yujin DAI Qiusheng ZHANG Xuezhu QU Xiaomei HUANG Jia LIU Xingdang 2008Nuclear Science and Techniques2008,19,2:0
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