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| 1 | Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis显示文摘AIM Evaluate the association between phase angle and the development of hepatic encephalopathy in the longterm follow-up of cirrhotic patients.METHODS This was a prospective cohort study. Clinical, nutritional and biochemical evaluations were performed. MannWhitney's U and χ2 tests were used as appropriate. Kaplan-Meier curves and Cox proportional Hazards analysis were used to evaluate the prediction and incidence of hepatic encephalopathy.RESULTS Two hundred and twenty were included; the most frequent etiology of cirrhosis was hepatitis C infection, 52% of the patients developed hepatic encephalopathy(18.6% covert and 33.3% overt); the main precipitating factors were infections and variceal bleeding. KaplanMeier curves showed a higher proportion of HE in the group with low phase angle(39%) compared to the normal phase angle group(13%)(P = 0.012). Furthermore, creatinine and phase angle remained independently associated to hepatic encephalopathy in the Cox regression multivariate analysis [hazard ratio = 1.80(1.07-3.03)]. CONCLUSION In our cohort of patients low phase angle was associated with an increased incidence of hepatic encephalopathy. Phase angle is a useful nutritional marker that evaluates cachexia and could be used as a part of the integral assessment in patients with cirrhosis. | Astrid Ruiz-Margáin Ricardo Ulises Macías-Rodríguez Javier Ampuero Francisco Javier Cubero Luis Chi-Cervera Silvia L Ríos-Torres Andrés Duarte-Rojo Ángeles Espinosa-Cuevas Manuel Romero-Gómez Aldo Torre | 2016 | World Journal of Gastroenterology2016，22，45： | 4 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Existence of global solutions for the Shigesada-Kawasaki-Teramoto model with weak cross-diffusion显示文摘 | Choi Y S Lui R Yamada Y | 2003 | Discrete Contin Dynam Systems2003，9，5： | 1 |
| 4 | Coding-and interference-aware routing protocol in wireless networks显示文摘 | HOU R QU S LUI K S | 2013 | Computer Communica- tions2013，36，17： | 1 |
| 5 | Existence of global solutions for the Shigesada-Kawasaki-Teramoto model with strongly coupled cross-diffusion显示文摘 | Choi Y S Lui R Yamada Y | 2004 | Discrete Contin Dynam Systems2004，10，3： | 1 |
| 6 | Associations of serum osteoprotegerin levels with diabetes,stroke,bone density,fractures,and mortality in elderly women 显示文摘 | LUI L Y CUMMINGS S R | 2001 | J Clin Endocrinol Metab2001，86，2： | 1 |
| 7 | Efficay of maintenance therapy after acute tocolysis: A meta-analysis显示文摘 | Luis S R A M Kaunitz F L Gaudier | 1999 | Am J Obstet Gynecol1999，181，2： | 1 |
| 8 | Derivative-free optimization: a review of algorithms and comparison of software implementations 显示文摘 | Luis M R Nikolaos V S | 2013 | Journal of Global Optimization2013，56，3： | 1 |
| 9 | Chromenes of polyketide oridin from Peperomia villipetiola 显示文摘 | Karina J M S Guillermo E D P Luis R L | 2005 | Phytochemistry2005，66，： | 1 |
| 10 | Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside显示文摘 | Araceli Sala M.Carmen Recio Guillermo R Schinella Salvador Má?ez Rosa M Giner Miguel Cerdá-Nicolás José-Luis R??os | 2003 | European Journal of Pharmacology2003，，1： | 1 |
| 11 | Hysteroscopic Dynamic Assessment of the Endometrium in Patients Treated with Long-Term Tamoxifen显示文摘 | Tirso Pérez-Medina Francisco J. Salazar Luis San-Frutos Mar Ríos Jesús S. Jiménez Juan Troyano Enrique Cayuela Enrique Iglesias | 2011 | The Journal of Minimally Invasive Gynecology2011，，3： | 1 |
| 12 | Parameter optimization of a planar BEGe detector using Monte Carlo simulations 显示文摘 | Lui's R | 2010 | Nucl Instr and Meth A2010，632，： | 1 |
| 13 | A distribution company energy acquisition market model with integration of distributed generation and load curtailment option显示文摘 | Palma-Behnke R Jose L C A Luis S V | 2005 | IEEE Trans on Power Systems2005，20，4： | 1 |
| 14 | Existence of global solutions for the Shigesada-Kawasaki-Teramoto model with strongly coupled cross-diffusion显示文摘 | Choi Y S Lui R Yamada Y | 2004 | Discrete Continuous Dynamics Systems2004，10，： | 1 |
| 15 | Pathophysiologic Mechanisms of Cardiovascular Disease in Obstructive Sleep Apnea Syndrome显示文摘 | Carlos Zamarrón Luis Valdés Cuadrado Rodolfo álvarez-Sala Francisco García Río | 2013 | <journal-title>Pulmonary Medicine2013，，： | 1 |
| 16 | Use of high-boiling point organicsolvents for pulping oil palm empty fruit bunches 显示文摘 | Alejandro R Luis S Ana M | 2008 | BioresourceTechnology2008，99，： | 1 |
| 17 | Human factors as a source of error in peak Doppler velocity measurement显示文摘 | Lui E Y Steinman A H Cobbold R S | 2005 | Journal of Vascular Surgery2005，42，5： | 1 |
| 18 | Density, heat capacity and thermal conductivity of liquid egg products 显示文摘 | Jane s R Coimbra Ana L G Luis A M | 2006 | Joumal of Food Engineering2006，74，： | 1 |
| 19 | Type Ⅲ secretion: The bacteria- eukaryotic cell express显示文摘 | Luis JM Isabel S Guy R | 2005 | FEMS Microbiol Lett2005，252，1： | 1 |
| 20 | Existence of Global Solutions for the Shigesada-Kawasaki-Teramoto Model with Strongly Coupled Cross-Diffusion显示文摘 | Choi Y S Lui R Yamada Y | 2004 | Discrete Contin Dyn Syst2004，10，3： | 1 |
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