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| 1 | Ownership and organizational performance: a comparison of technical efficiency across hospital types 显示文摘 | Ozcan Y A Luke R D Haksever G | 1992 | Medical Care1992，30，9： | 1 |
| 2 | Oral administration of protease inhibits enterotoxigenic Escheriehia coli receptor activity in piglet small intestine显示文摘 | Mynott T L Luke R K Chandler D S | 1996 | Gut1996，38，： | 1 |
| 3 | Declining rates of physical activity in the United States: What are the contribu- tors? 显示文摘 | BROWNSON R C BOEHMER T K LUKE D A | 2005 | Annu Rev Public Health2005，26，： | 1 |
| 4 | Molecular dynamics study of solid thin film thermal conductivity 显示文摘 | Lukes J R Li D Y LIANG X G | 2000 | ASME J Heat Transfer2000，122，： | 1 |
| 5 | Molecular dynamics study of solid thin-film thermal conductivity显示文摘 | Lukes J R Li D Y Liang X G | 2000 | Journal of Heat Transfer2000，122，： | 1 |
| 6 | Strategic hospital alli-ances:do the type and market structure of strategic hospital alli-ances matter?显示文摘 | MCCUE M J CLEMENT J P LUKE R D | 1999 | Medical care1999，37，10： | 1 |
| 7 | Molecular dynamics study of solid thin-film thermal conductivity显示文摘 | Lukes J R Li D Y Liang X G | 2000 | Journal of Heat Transfer2000，122，3： | 1 |
| 8 | Genetic associations of inflammatory bowel disease in a South Asian population显示文摘AIM To estimate prevalence and phenotypic associations of selected inflammatory bowel disease(IBD)-associated genetic variants among Sri Lankan patients. METHODS A case study of histologically confirmed ulcerative colitis(UC) or Crohn's disease(CD) patients with ≥ 1 year disease duration, who were compared to unrelated, gender-matched, healthy individuals as controls, was conducted at four major centers in Sri Lanka. Phenotypic data of the cases were obtained and all participants were genotyped for 16 selected genetic variants: IL12 B :rs1045431, IL23 R :rs11805303, ARPC2 :rs12612347, IRGM :rs13361189, IL26/IL22 :rs1558744, CDH1 :rs1728785, IL10 :rs3024505, FCGR2 A :rs3737240, PTGER4 :rs4613763, IL17 REL/PIM3 :rs5771069, HNF4 a :rs6017342, STAT3 :rs744166, SMURF1 :rs7809799, LAMB1 :rs886774, HLA-DRB5, DQA1, DRB1, DRA :rs9268853, MST1, UBA7, and APEH :rs9822268. The genotypes of all variants were in Hardy-Weinberg Equilibrium(P > 10^(-3)). To account for multiple hypothesis testing, P-values < 0.003 were considered significant.RESULTS A total of 415 patients and 465 controls were recruited. Out of the single nucleotide polymorphisms(SNPs) tested, the majority were not associated with IBD in Sri Lankans. Significant positive associations were noted between rs886774(LAMB1-gene) and UC(odds ratio(OR) = 1.42, P = 0.001). UC patients with rs886774 had mild disease(OR = 1.66, P < 0.001) and remained in remission(OR = 1.48, P < 0.001). A positive association was noted between rs10045431(IL 12 B gene) and upper gastrointestinal involvement in CD(OR = 4.76, P = 0.002). CONCLUSION This confirms the heterogeneity of allelic mutations in South Asians compared to Caucasians. Most SNPs and disease associations reported here have not been described in South Asians. | Madunil Anuk Niriella Isurujith Kongala Liyanage Senerath Kuleesha Kodisinghe Arjuna Priyadarsin De Silva Nimna Rajapakshe Sunali D Nanayakkara Dunya Luke Thilakshi Silva Metthananda Nawarathne Ranjith K Peiris Udaya P Kalubovila Sujeewa R Kumarasena Vajira Harshadeva Weerabaddana Dissanayake Rohan W Jayasekara Hithanadura Janaka de Silva | 2018 | World Journal of Clinical Cases2018，6，15： | 1 |
| 9 | Methylisocyanate:an evaluation of in vivo cytogeneticactivity显示文摘 | Tice R R Luke C A Shelby M D | 1987 | Environmental Mutagenesis1987，，9： | 1 |
| 10 | Perceptions of neighborhood environment for physical activity,Is it 'Who you are ' or 'Where you live'显示文摘 | BOSLAUGH S E LUKE D A BROWNSON R C | 2004 | J Urban Health2004，81，4： | 1 |
| 11 | Effects of dietary lipid levels on growth performance of marbled spinefoot rabbitfish Siganus rivula- tus显示文摘 | JOLY G LUKE R D ALLEN D | 2011 | Aquaculture2011，310，34： | 1 |
| 12 | Effects of dietary lipid levels on growth performance of marbled spinefoot rabbiffish Siganus rivulatus显示文摘 | Joly G Luke R D Allen D | 2011 | Aquacuhure2011，310，34： | 1 |
| 13 | Effects of cyclosporine on the isolated perfused rat kidney 显示文摘 | LUKE D R KASISKE B L MATZKE G R | 1987 | Transplantation1987，43，6： | 1 |
| 14 | Optical wavefront reconstruction:theory and numerical methods显示文摘 | D R Luke J V Burke R G Lyon | 2002 | Society for Industrial and Applied Mathematics2002，44，2： | 1 |
| 15 | Molecular dynamics study of solid thin-film thermal conductivity显示文摘 | Lukes J R Li D Y Liang X G Tien C L | 2000 | Journal of Heat Transfer2000，122，： | 1 |
| 16 | A portable X-ray fluorescence instrument for analyzing dust wipe samples for lead: Evaluation with field samples 显示文摘 | Sterling D A Lewis R D Luke D A Shadel B N | 2000 | Environmental Research2000，83，2： | 1 |
| 17 | Forty years of secondhand smoke research: The gap between discovery and delivery 显示文摘 | Harris J K Luke D A Zuckerman R B | 2009 | American Journal of Preventive Medicine2009，36，6： | 1 |
| 18 | Forty years of secondhand smoke research:The gap between discovery and delivery显示文摘 | Harris J K Luke D A Zuckerman R B | | 0，，06： | 1 |
| 19 | Alternating projections and Douglas-Rachford for sparse affine feasibility显示文摘 | Hesse R Luke D R and Neumann P | 2014 | IEEE Transactions on Signal Processing2014，62，18： | 1 |
| 20 | Declining rates of physical activity in the United States: what are the contributors? 显示文摘 | BROWNSON R C BOEHMER T K LUKE D A | 2005 | Annual Rev Public Health2005，26，： | 1 |
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