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| 1 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 2 | Stability of the lumbar spine after intradiscal electrothermal therapy显示文摘 | Lee J Lutz GE Campbell D | 2001 | Arch Phys Med Rehabil2001，82，1： | 1 |
| 3 | Efficacy of interferon-gamma and amphotericin B for the treatment of systemic murine histoplasmosis显示文摘 | Clemons K V Lutz J E Stevens D A | 2001 | Microbes Infect2001，3，： | 1 |
| 4 | Single impact trauma in human early-stage osteoarthritic cartilage:Implication of prostaglandin D2 but no additive effect of IL-1β on cell survival显示文摘 | Helga Joos Cathrin Hogrefe Lucia Rieger Lutz Dürselen Anita Ignatius Rolf Brenner | 2011 | International Journal of Molecular Medicine2011，，： | 1 |
| 5 | Analysis of endogenous cortisol concentrations in the hair of rhesus macaques 显示文摘 | DAVENPORT M D TIEFENBACHER S LUTZ C K | 2006 | General and Comparative Endocrinology2006，147，： | 1 |
| 6 | Effect of COX inhibitors on VEGF-induced retinal vascular leakage and experimental corneal and choroidal neovascularization显示文摘 | Castro MR Lutz D Edelman JL | 2004 | Exp Eye Res2004，79，2： | 1 |
| 7 | Effect of relative impeller-to-volute position on hydraulic efficiency and static radial force distribution in a circular volute cen- trifugal pump 显示文摘 | Daniel O B Lutz K Ronald D F | 2000 | Transactions of the ASME2000，122，3： | 1 |
| 8 | Preparation of segmented copolymers in the presence of an immobilized/soluble hybrid atrp catalyst system显示文摘 | Hong S C Neugebauer D Inoue Y Lutz J-F Matyjaszewski K | 2003 | Macromolecules2003，36，1： | 1 |
| 9 | Structure Refinement of Skutterudite-Type Cobalt Triantimonide, CoSb3 显示文摘 | Schmidt T Kliche G Lutz H D | 1987 | Acta Crystallographica Section C1987，43，： | 1 |
| 10 | Cross-talk of vitamin D and glucocorticoids in hippocampal cells 显示文摘 | Obradovic D Gronemeyer H Lutz B | 2006 | J Neurochem2006，96，2： | 1 |
| 11 | Neogenin Mediates the Action of Repulsive Guidance Molecule显示文摘 | SRIKANTH R LUTZ D DAVIS D | 2004 | Nature cell biology(S1465-7392)2004，6，8： | 1 |
| 12 | The land mobile satellite communication channel-recording,statistics and channel model显示文摘 | Lutz E Cygan D Dippold M | 1991 | IEEE Transactions on Vehicular Technology1991，40，2： | 1 |
| 13 | Dynamic Avalanche and Reliability of High Voltage Diodes显示文摘 | M D Josef Lutz | 2002 | Microelectronics Reliability2002，43，5： | 1 |
| 14 | The effect of parental expectations on treatment of children with a cough:a report from ASPN显示文摘 | Vinson D C Lutz L J | | 0，，1： | 1 |
| 15 | Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis显示文摘 | Lutz D Gazdhar A Lopez-Rodriguez E | 2015 | American journal of respiratory cell and molecular biology2015，52，2： | 1 |
| 16 | Quantum corrals显示文摘 | Crommie M F Lutz C P Eigier D M | 1995 | Physica D1995，83，： | 1 |
| 17 | Heteroplasmy in the mtDNA control region of sturgeon(Acipenser,Huso and Scaphirhynchus) 显示文摘 | Arne L Bernie M Lutz D | 2000 | Genetics2000，156，： | 1 |
| 18 | The FMR-1 protein is cytoplas-mic, most abundant in neurons and appears normal in carriers of afragile X premutation显示文摘 | Devys D Lutz Y Rouyer N | 1993 | Nat Genet1993，4，4： | 1 |
| 19 | Mycoplasma pneumoniae antigens stimulate interleukin-8 显示文摘 | CI-IMURA K LUTZ R D CHIBA H | 2003 | Chest2003，123，3： | 1 |
| 20 | Number bias for the discrimination of large visual sets in infancy显示文摘 | Brannon E.M Abbott S Lutz D | | 0，，： | 1 |
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