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| 1 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 2 | Processing stoichiometric silicon carbide fibers from polymethylsilane, part I precursor fiber processing显示文摘 | ZHANG Z F SCOTTO C S LAINE R M | 1998 | J Mater Chem1998，8，： | 2 |
| 3 | The CCN family of angiogenic regulators : the integrin connection 显示文摘 | Lau L F Lain S C | 1999 | Exp Cell Res1999，248，1： | 1 |
| 4 | Targeting Mnks for cancer thera- py显示文摘 | Hou J Lain F Proud C | 2012 | Oncotarget2012，3，2： | 1 |
| 5 | Moment-resisting bolted timber connections显示文摘 | Lain F Gehloff M Closen M | 2010 | Structures and Buildings2010，163，4： | 1 |
| 6 | Localization of damage structural connections based on experimental modal and sensitivity analysis显示文摘 | Lain H F Ko J M Wong C W | 1998 | Journal of Sound and Vibration1998，210，1： | 1 |
| 7 | Polyhedral phenylsilsesquioxanes显示文摘 | LAINE R M ROLL M F | | 0，，03： | 1 |
| 8 | Gelling agent influences the detrimental effect of kanamycin on adventitious budding in tlax显示文摘 | Laine E Lamblin F Lacoux J | 2000 | Plant Cell Tissue and Organ Culture2000，63，： | 1 |
| 9 | Wavelet descriptors for multiresolution recognition of handprinted characters显示文摘 | Wunsch P Laine A F | | Pattern Recognition0，，28： | 1 |
| 10 | Speckle reduction and contrast enhancement of echocardiograms via multiscale nonlinear processing 显示文摘 | Zong X Laine A F Geiser E A | 1998 | IEEE Transactions on Medical Imaging1998，17，4： | 1 |
| 11 | Circle recognition through a 2D Hough transform and radius histogramming显示文摘 | IOANNOU D HUDA W LAINE A F | 1999 | Image and Vision Gomputing1999，17，1： | 1 |
| 12 | Risk to breeding success of ardeidae by contaminants in Hong Kong: evidence from trace metals in feathers 显示文摘 | CormelD W WongB S F Lain P K S | 2002 | Ecotoxicology2002，11，： | 1 |
| 13 | Outcomes in persistent hyperplastic vitreous 显示文摘 | Hunt A Rowe N Lain A Martin F | 2005 | Br J Ophthalmol2005，89，： | 1 |
| 14 | Speckle reduction and contrast enhancement of echocardiograms via multiscale nonlinear processing 显示文摘 | Zong Xuli Laine Andrew F Geiser Edward A | 1998 | IEEE Transactions on Medical Imaging1998，17，4： | 1 |
| 15 | Molecular mechanisms of eytokine and ehemokine release from eosinophils activated by IL-17A, IL-17F and IL- 23: implication for Thl7 lymphocytes--mediated allergic inflammation 显示文摘 | Cheung P F Wong C K Lain C W | 2008 | J hnmunol2008，180，8： | 1 |
| 16 | Mammographic feature enhancement by multiscale analysis显示文摘 | Laine A F Schuler S Fan J | 1994 | IEEE Transactions on Medical Image1994，13，4： | 1 |
| 17 | Preceramic polymer routes to silicon carbide 显示文摘 | LAINE R M BABONNEAU F | 1993 | Chem Mater1993，5，： | 1 |
| 18 | Circle recognition through a 2D Hough Transform and radius histogramming显示文摘 | Ioannou D Huda W Laine A F | 1999 | Image and Vision Computing1999，17，： | 1 |
| 19 | The use of the phosphomannose isomerase gene as alternative selectable marker for Agrobacterium-mediated transformation of flax (Linum usitatissimum)显示文摘 | Lamblin F Aime A Hano C Roussy I Domon J M Droogenbroeck B V Laine E | | 0，，26： | 1 |
| 20 | The lived space of mathematics learning 显示文摘 | Wong N Y Marton F Wong K M Lain C C | 2002 | ?Joumal of Mathematical Behavior2002，，21： | 1 |
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