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| 1 | Glucagon-like peptide-1 receptor agonists in non-alcoholic fatty liver disease: An update显示文摘Non-alcoholic fatty liver disease(NAFLD)is the predominant cause of chronic liver disease worldwide.NAFLD progresses in some cases to non-alcoholic steatohepatitis(NASH),which is characterized,in addition to liver fat deposition,by hepatocyte ballooning,inflammation and liver fibrosis,and in some cases may lead to hepatocellular carcinoma.NAFLD prevalence increases along with the rising incidence of type 2 diabetes mellitus(T2DM).Currently,lifestyle interventions and weight loss are used as the major therapeutic strategy in the vast majority of patients with NAFLD.Glucagon-like peptide-1 receptor agonists(GLP-1RAs)are used in the management of T2DM and do not have major side effects like hypoglycemia.In patients with NAFLD,the GLP-1 receptor production is down-regulated.Recently,several animal and human studies have emphasized the role of GLP-1RAs in ameliorating liver fat accumulation,alleviating the inflammatory environment and preventing NAFLD progression to NASH.In this review,we summarize the updated literature data on the beneficial effects of GLP-1RAs in NAFLD/NASH.Finally,as GLP-1RAs seem to be an attractive therapeutic option for T2DM patients with concomitant NAFLD,we discuss whether GLP-1RAs should represent the first line pharmacotherapy for these patients. | Areti Sofogianni Athanasios Filippidis Lampros Chrysavgis Konstantinos Tziomalos Evangelos Cholongitas | 2020 | World Journal of Hepatology2020，12，8： | 5 |
| 2 | Management and control applications in Agriculture domain via a Future Internet Businessto- Business platform显示文摘The Agriculture business domain,as a vital part of the overall supply chain,is expected to highly evolve in the upcoming years via the developments,which are taking place on the side of the Future Internet.This paper presents a novel Business-to-Business collaboration platform from the agri-food sector perspective,which aims to facilitate the collaboration of numerous stakeholders belonging to associated business domains,in an effective and flexible manner.The contemporary B2B collaboration schemes already place the requirements for swift deployment of cloud applications,capable of both integrating diverse legacy systems,as well as developing in a rapid way new services and systems,which will be able to instantly communicate and provide complete,'farm-to-fork'solutions for farmers,agrifood and logistics service providers,ICT companies,end-product producers,etc.To this end,this conceptual paper describes how these requirements are addressed via the FIspace B2B platform,focusing on the Greenhouse Management&Control scenarios. | Sokratis Barmpounakis Alexandros Kaloxylos Aggelos Groumas Lampros Katsikas Vasileios Sarris Konstantina Dimtsa Fabiana Fournier Eleni Antoniou Nancy Alonistioti Sjaak Wolfert | 2015 | Information Processing in Agriculture2015，2，1： | 4 |
| 3 | Effect of glycemic control on markers of subclinical atherosclerosis in patients with type 2 diabetes mellitus:A review显示文摘Cardiovascular disease is the predominant cause of death in type 2 diabetes mellitus(T2DM).Evidence suggests a strong association between duration and degree of hyperglycemia and vascular disease.However,large trials failed to show cardiovascular benefit after intensive glycemic control,especially in patients with longer diabetes duration.Atherosclerosis is a chronic and progressive disease,with a long asymptomatic phase.Subclinical atherosclerosis,which is impaired in T2DM,includes impaired vasodilation,increased coronary artery calcification(CAC),carotid intima media thickness,arterial stiffness,and reduced arterial elasticity.Each of these alterations is represented by a marker of subclinical atherosclerosis,offering a cost-effective alternative compared to classic cardiac imaging.Their additional use on top of traditional risk assessment strengthens the predictive risk for developing coronary artery disease(CAD).We,herein,review the existing literature on the effect of glycemic control on each of these markers separately.Effective glycemic control,especially in earlier stages of the disease,attenuates progression of structural markers like intima-media thickness and CAC.Functional markers are improved after use of newer antidiabetic agents,such as incretin-based treatments or sodium-glucose cotransporter-2 inhibitors,especially in T2DM patients with shorter disease duration.Larger prospective trials are needed to enhance causal inferences of glycemic control on clinical endpoints of CAD. | Sofia Antoniou Katerina K K Naka Marios Papadakis Aris Bechlioulis Agathocles Tsatsoulis Lampros K Michalis Stelios Tigas | 2021 | World Journal of Diabetes2021，12，11： | 2 |
| 4 | Nonalcoholic fatty liver disease in lean subjects:Prognosis,outcomes and management显示文摘Nonalcoholic fatty liver disease(NAFLD)accounts for most cases of chronic liver disease worldwide,with an estimated global prevalence of approximately 25%and ranges from simple steatosis to nonalcoholic steatohepatitis and cirrhosis.NAFLD is strongly connected to metabolic syndrome,and for many years,fatty liver was considered to be an exclusive feature of obese patients.However,recent studies have highlighted the presence of NAFLD in non-obese subjects,with or without increased visceral fat or even in lean subjects without increased waist circumference.“Lean NAFLD”is a relatively new concept and there is significant scientific interest in understanding the differences in pathophysiology,prognosis and management compared with NAFLD in overweight/obese patients.In the present editorial,we discuss the clinical and metabolic profiles and outcomes of lean NAFLD compared with both obese NAFLD and lean healthy individuals from Asian and Western countries.Moreover,we shed light to the challenging topic of management of NAFLD in lean subjects since there are no specific guidelines for this population.Finally,we discuss open questions and issues to be addressed in the future in order to categorize NAFLD patients into lean and nonlean cohorts. | Lampros Chrysavgis Eleftheria Ztriva Adonis Protopapas Konstantinos Tziomalos Evangelos Cholongitas | 2020 | World Journal of Gastroenterology2020，26，42： | 2 |
| 5 | Roadmapping as a knowledge creation process: the prolearn roadmap显示文摘 | VANA KAMTSIOU AMBJORN NAEVE LAMPROS K | 2006 | Journal of Universal Knowledge Management2006，1，3： | 1 |
| 6 | Exercise-mediated adaptations in vascular function and structure:Beneficial effects in coronary artery disease显示文摘Exercise exerts direct effects on the vasculature via the impact of hemodynamic forces on the endothelium,thereby leading to functional and structural adaptations that lower cardiovascular risk.The patterns of blood flow and endothelial shear stress during exercise lead to atheroprotective hemodynamic stimuli on the endothelium and contribute to adaptations in vascular function and structure.The structural adaptations observed in arterial lumen dimensions after prolonged exercise supplant the need for acute functional vasodilatation in case of an increase in endothelial shear stress due to repeated exercise bouts.In contrast,wall thickness is affected by rather systemic factors,such as transmural pressure modulated during exercise by generalized changes in blood pressure.Several mechanisms have been proposed to explain the exercise-induced benefits in patients with coronary artery disease(CAD).They include decreased progression of coronary plaques in CAD,recruitment of collaterals,enhanced blood rheological properties,improvement of vascular smooth muscle cell and endothelial function,and coronary blood flow.This review describes how exercise via alterations in hemodynamic factors influences vascular function and structure which contributes to cardiovascular risk reduction,and highlights which mechanisms are involved in the positive effects of exercise on CAD. | Xenofon M Sakellariou Michail I Papafaklis Eleni M Domouzoglou Christos S Katsouras Lampros K Michalis Katerina K Naka | 2021 | World Journal of Cardiology2021，13，9： | 1 |
| 7 | Noncosmetic benefits of single-incision laparoscopic sigmoid colectomy for diverticular disease: A case-matched comparison with multiport laparoscopic technique显示文摘 | Vasileios Vasilakis Clarence E. Clark Lampros Liasis Harry T. Papaconstantinou | 2012 | Journal of Surgical Research2012，，： | 1 |
| 8 | Explicit Window Adaptation: A Method to Enhance TCP Performance 显示文摘 | Lampros K Anujan V | 2002 | IEEE/ACM Transactions on Networking2002，10，3： | 1 |
| 9 | Explicit window adaptation:a method to enhance TCP performance 显示文摘 | Lampros K Anujan V | 2002 | IEEE/ACM Transactions on Networking2002，10，3： | 1 |
| 10 | Extended Kalman filtering with stochastic nonlinearities and multiple missing measurements显示文摘 | Jun Hu Zidong Wang Huijun Gao Lampros K. Stergioulas | 2012 | Automatica2012，，9： | 1 |
| 11 | A water balance derived drought index for Pinios river basin,Greece显示文摘 | Lampros V Athanasios L Nikos L | 2011 | Water Resource Manage2011，25，4： | 1 |
| 12 | Stress and Springback Analyses of API X70 Pipeline Steel Under 3-Roller Bending via Finite Element Method显示文摘3-Roller bending is a widely applied manufacturing process, particularly in structural steel pipe industry.However, due to the difficulty and high cost of measuring stress distribution inside sheet material via traditional method,internal stress/strain response during forming is largely unexplored. The focuses of this study are two:(1) to map the radii of curvature as well as the stress inside the work piece during forming by utilizing the meshing mechanism of finite element method, and(2) to further provide some numeric guidelines for the configuration of the rolling system in order to improve production efficiency and product quality. The results of this study indicate that:(1) it is crucial to properly choose forming parameter in order to produce product with desired radii;(2) much like a gradual springback process, the radii of curvature gradually increase from the top roller to the exit-side bottom roller;(3) under the assumptions made in this study, to produce pipes with a specified diameter with varying configurations of the 3-roller system will not significantly change the final residual stress; and(4) finally, shifting of the neutral axis up to 2.0% of the thickness toward the compressing side during the forming process is observed. | Wenbo Zhao T.Warren Liao Lampros Kompotiatis | 2017 | Acta Metallurgica Sinica(English Letters)2017，30，5： | 1 |
| 13 | Randomized comparison of virtual microscopy and traditional glass mi- croscopy in diagnostic accuracy among dermatology and pa- thology residents显示文摘 | Koch LH Lampros JN Delong LK | 2009 | Hum Pathol2009，40，： | 1 |
| 14 | Discrete subaortic stenosis:an ac-quired heart disease显示文摘 | Lampros TD Cobanoglu A | | European Journal of Cardio-Thoracic Surgery0，，： | 1 |
| 15 | Long-Term Results After Adult Ex Situ Split Liver Transplantation Since Its Introduction in 1987显示文摘 | Harald Schrem Moritz Kleine Tim Oliver Lankisch Alexander Kaltenborn Lampros Kousoulas Lea Zachau Frank Lehner Jürgen Klempnauer | 2014 | World Journal of Surgery2014，，7： | 1 |
| 16 | Higher order nested Wigner distribution: properties and applications 显示文摘 | Saad A Q Lampros K S | 2006 | IEEE Transactions on Signal Processing (S1053-587X)2006，54，12： | 1 |
| 17 | Angiographic Stent Thrombosis After Routine Use of Drug-Eluting Stents in ST-Segment Elevation Myocardial Infarction显示文摘 | Georgios Sianos Michail I. Papafaklis Joost Daemen Sofia Vaina Carlos A. van Mieghem Ron T. van Domburg Lampros K. Michalis Patrick W. Serruys | 2007 | Journal of the American College of Cardiology2007，，： | 1 |
| 18 | Non-alcoholic fatty liver disease and hepatocellular carcinoma:Clinical challenges of an intriguing link显示文摘Non-alcoholic fatty liver disease(NAFLD)has emerged as the most common liver disorder worldwide mainly attributed to the epidemic spread of obesity and type 2 diabetes mellitus.Although it is considered a benign disease,NAFLD can progress to non-alcoholic steatohepatitis,liver cirrhosis and hepatocellular carcinoma(HCC).Most data regarding the epidemiology of NAFLD-related HCC are derived from cohort and population studies and show that its incidence is increasing as well as it is likely to emerge as the leading indication for liver transplantation,especially in the Western World.Although cirrhosis constitutes the main risk factor for HCC development,in patients with NAFLD,HCC can arise in the absence of cirrhosis,indicating specific carcinogenic molecular pathways.Since NAFLD as an underlying liver disease for HCC is often underdiagnosed due to lack of sufficient surveillance in this population,NAFLDHCC patients are at advanced HCC stage at the time of diagnosis making the management of those patients clinically challenging and affecting their prognostic outcomes.In this current review,we summarize the latest literature on the epidemiology,other than liver cirrhosis-pathogenesis,risk factors and prognosis of NAFLD-HCC patients.Finally,we emphasize the prevention of the development of NAFLD-associated HCC and we provide some insight into the open questions and issues regarding the appropriate surveillance policies for those patients. | Lampros Chrysavgis Ilias Giannakodimos Panagiota Diamantopoulou Evangelos Cholongitas | 2022 | World Journal of Gastroenterology2022，28，3： | 1 |
| 19 | Comparative diagnos- tic accuracy in virtual dermatopathology 显示文摘 | MOONEY E HOOD AF LAMPROS J | 2011 | Skin Res Technol2011，17，7： | 1 |
| 20 | Hydrological response to meteorological drought using the Palmer drought indices in Thessaly,Greece显示文摘 | Lampros Vasiliades Athanasios Loukas | 2009 | Desalination2009，237，： | 1 |
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