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| 1 | Anti-diabetic effect of aloin via JNK-IRS1/PI3K pathways and regulation of gut microbiota显示文摘This research aimed to investigate the antidiabetic activity,underlying mechanisms,and gut microbiota regulation of aloin.The insulin-resistant HepG2(IR-HepG2)cell model and the type 2 diabetic(T2D)mouse model were successfully established using dexamethasone and a high-fat high-sucrose diet with low-dose streptozotocin,respectively.Aloin intervention increased glucose consumption and stimulated the activity of hexokinase and pyruvate dehydrogenase in IR-HepG2 cells.Additionally,it diminished the weight loss,reduced fasting blood glucose levels and hemoglobin A1c activity,and promoted glucose tolerance and fasting serum insulin activity in T2D mice.Histopathological analysis of the liver indicated hepatic protection by aloin.Additionally,aloin treatment inhibited the protein expression of c-Jun N-terminal kinases and activated that of IRS1/PI3K/Akt in the liver.Moreover,aloin modulated the bacterial community in the gut by raising the abundance of Bacteroidota and reducing the richness of Firmicutes,Proteobacteria,and Actinobacteriota.Thus,aloin ameliorated IR via activating IRS1/PI3K/Akt signaling pathway and regulating the gut microbiota,and it may be promising candidate as functional food for diabetic therapy. | Ruting Zhong Lanbin Chen Yuanyuan Liu Shouxia Xie Sumei Li Bin Liu Chao Zhao | 2022 | Food Science and Human Wellness2022，11，1： | 2 |
| 2 | Application of an exhaust heat recovery system for domestic hot water显示文摘 | Lanbin Liu Lin Fu Yi Jiang | 2010 | Energy2010，35，14： | 1 |
| 3 | Polybaric partial melting in the continental mantle:Evidence from mantle xenoliths from Qilin,Guangdong Province显示文摘The extremely low Ti content (160-245μg/g) in clinopyroxene in some spinel peridotites from Qilin, South China is indicative of high degree of partial melting, inconsistent with their relatively high clinopyroxene modes (7.4%-12.4%). These clinopyroxenes show fractionated HREE patterns ((Gd/Yb)n<0.2), suggesting the involvement of garnet in the melting regime. These REE patterns can be modeled as residues of 22%-23% fractional melting from a primitive mantle, first in garnet stability field (12%) then continuing in spinel stability field (10%-11%) after breakdown of garnet to pyroxenes and spinel. Such a polybaric melting suggests the lithospheric thinning and rapid mantle upwelling in south China during the Cenozoic. This is consistent with the dominant MORB-OIB isotopic signature and high thermal gradient of the lithospheric mantle in this region, and supports the contention that the formation of South China Sea basin is related to southward migration of continental lithosphere extension, rather | XU Yigang VAN Wen SUN Min LIU Ying HE Zaicheng SHI Lanbin | 2001 | Chinese Science Bulletin2001，46，20： | 1 |
| 4 | Application of an exhaust heat recovery system for domestic hot water显示文摘 | Liu Lanbin Fu Lin Jiang Yi | 2010 | Energy2010，35，3： | 1 |
| 5 | A subspace based method for modelling building’s thermal dynamic in district heating system and parameter extrapolation verification显示文摘The district heating system(DHS)consumes a lot of energy in winter,and its control accuracy needs to be improved urgently.To apply advanced process control(APC)in DHS,the thermal dynamic model of the existing buildings is essential.This paper uses the subspace method which is a data-driven approach for modelling the thermal dynamics of the building.The model’s performance is analyzed using the collected data,and the differences compared to the classical methods are also analyzed.The method reduces the RMSE by about 20%compared with the ARX model for the same complexity.Subsequently,the analysis of the training residuals indicates that the estimate of periodic intra-building disturbance can be obtained by minimizing the training residuals.By introducing the estimated disturbance function,the RMSE on the test set is further reduced by 26%.At the end of the article,a simple parameter extrapolation experiment is conducted,and the result shows that the parameters can be extrapolated to other buildings without large errors. | Junfeng Zhang Lanbin Liu Yameng Liu | 2023 | Building Simulation2023，16，11： | 0 |
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