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108篇 您的检索式:作者名="LauG"
    题名 作者 年代 出处 被引量
1人脑胶质瘤细胞裸鼠原位移植动物模型的建立显示文摘目的探讨人脑胶质瘤细胞裸鼠原位移植动物模型建立的技术方法。方法借助动物立体定向仪的引导,采用微注射方法将体外培养人脑胶质瘤细胞U87MG(悬浮于无血清RPMI 1640培养液中,细胞数为108/ml)接种于裸鼠(BALB/c)额叶白质区。接种后观察不同种实验鼠的生存状态,分别于接种后1 h至63 d的不同时间进行裸鼠脑肿瘤组织病理学检查和免疫组织化学分析。结果裸鼠脑内注射体外培养的人脑胶质瘤细胞U87MG的合适速率为0.05μl/min =1μl/20 min,细胞悬液体积1μl,细胞数105,注射时间20 min。按此方案注射U87MG细胞无沿针道返流,恰好在尾状核区形成近圆球形肿瘤体,成瘤率高(100%),肿瘤颅内生长稳定,组织病理学检查符合人脑胶质瘤形态特征,未见脑外转移。结论本研究的人脑胶质瘤细胞裸鼠原位移植动物模型建立方法精确可靠,重复性好。肿瘤符合人脑胶质瘤的生物学特性,该动物模型可作为研究人脑胶质瘤发生、生物学特性以及各种治疗评价的可靠动物模型。步星耀 章翔 Walter E. Laug 2006中华神经外科疾病研究杂志2006,5,2:14
2河边过渡带养分的持留显示文摘本文对河边过渡带的养分持留机制进行了探讨,重点放在地表径流和地下潜流上,这是河流与其周围环境进行物质交换的两条主要途径。河边过渡带独特的物理和生物地球化学性质决定着高地与河流之间的水、养分和其他外源物质的流动。地表入河水流中养分的持留是由带有养分的泥沙沉降以及溶解的养分与土壤和枯落物层的交换完成的。潜流中氮的持留,部分可由植被吸收来解释,但其主要机制通常是脱氮作用。对渠道化的河流来说,在大多数情况下,入河潜流都改经排涝管排放,从而使交换水流(即经河床与河岸进出明渠的水流)大大减少。因此,要提高这种河流中的氮的持留量,就必须对其进行截流,或者通过恢复旧河道或在缓冲带建立人工设施等措施使其重归故道。Lena B.-M.Vought Jonas Dahl Carsten Lauge Pedersen JeanO.Lacoursière 安逸 1994人类环境杂志1994,23,6:2
3Effects of high temperature shocks on the development and biology of Trichogramma brassicae(Hym:Trichogrammadae)显示文摘Chihrane J Laugé G Hawlitzky 1993Entomophaga1993,38,2:1
4Fungal avirulence genes: Structure and possible functions显示文摘Lauge R De Wit PJ 1998Fungal Geneticsand Biology1998,24,3:1
5Effects of high temperatures recorded during diapause completion of Trichogramma brassicae prepupae(Hym:Trichogrammadae),on the treated generation and its progeny 显示文摘Gune G Laugé G 1997Entomophaga1997,42,3:1
6Numerical modeling of nanostructured materials显示文摘BENABBOU A BOROUCHAKI H LAUG P 2010Finite Elements in Analysis and Design2010,46,12:1
7An in-plane thermal unimorph using confined polymers 显示文摘LAUG K DUCTC GOOSENJ F L 2007J Micromech Microeng2007,17,:1
8Plasminogen activator inhibitor-1 promotes angiogensis by stimulating endothelial cell migration toward fibronectin显示文摘Isogai C Laug W E Shimada H 2001Cancer Res2001,61,14:1
9Peginterferon ct-2a as monotherapy and in combination with HBeAg positivechronic hepatitis B显示文摘Laug KK Piratvisut HT Luo KX 2004Hepatology2004,38,1:1
10Reproducibility and validity of radiographically determined gastrointestinal and segmental colonic transit times in spinal cord injured patients 显示文摘Media S Christensen P Lauge I 2009Spinal Cord2009,47,1:1
11Clinical correlations with Lewy body pathology in LRRK2 - related Parkinson disease 显示文摘Kalia LV Laug AE Hazarti LN 2015JAMA Neurol2015,72,1:1
12Urokinase induces receptor mediated brain tumor cell migration and invasion显示文摘MacDonald TJ DeClerck YA Laug WE 1998J Neurooncol1998,40,3:1
13Fungal avirulence genes: structure and possible functions 显示文摘Lauge R De Wit P J 1998Fungal Genetics and Biology1998,24,3:1
14Urokinase induces receptor mediated brain tumor cell migration and invasion显示文摘MacDonald TJ DeClerck YA Laug WE 1998J Neurooncol1998,40,3:1
15Urokinase induces receptor mediated brain tumor cell migration and invasion显示文摘MacDonald TJ DeClerck YA Laug WE 1998J Neurooncol1998,40,:1
16Reducing stress on cells with apoferritin-encapsulated platinum nanoparticles显示文摘ZHANG Lianbing LAUG L MUNCHGESANG W 2010Nano Letters2010,10,1:1
17Spatial mismatch and the affordability of public transportfor the poor in Singapore's new towns显示文摘LauG C 2011Cities2011,28,3:1
18Platelet response to aspirin and clopidogrel in patients with peripheral atherosclerosis显示文摘Esben Hjorth Madsen Norbert Rudolf Gehr Nils Lauge Johannesen Erik Berg Schmidt S? ren Risom Kristensen 2011Platelets2011,,:1
19Surface mesh enhancement with geometric singularities identification显示文摘Borouchaki H Villard J Laug P 2005Computer Methods in Applied Mechanics and Engineering2005,194,48:1
20Ecidence of peripheral bloodderved,plastec-adherent CD34-he matopoietice stem cell clones with mesenchymal stem cell characteristics显示文摘 Lauge C weissinger EM 2000Slem Cells2000,18,4:1
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