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| 1 | Nutritional and health benefits of semi-elemental diets: A comprehensive summary of the literature显示文摘AIM:To critically review and summarize the literature on nutritional and health outcomes of semi-elemental formulations on various nutritionally vulnerable patient populations who are unable to achieve adequate nutrition from standard oral diets.METHODS:We conducted a comprehensive literature search of Pubmed and Embase databases.We manually screened articles that examined nutritional and health outcomes(e.g.,growth,disease activity,gastrointestinal impairment,mortality,and economic impact)among various patient groups receiving semi-elemental diets.This review focused on full-text articles of randomized controlled clinical trials and other intervention studies,but pertinent abstracts and case studies were also included.Results pertaining primarily to tolerance,digestion,and absorption were summarized for each patient population in this systematic review.RESULTS:Results pertaining primarily to tolerance,digestion,and absorption were summarized for each patient population.The efficacy of semi-elemental whey hydrolyzed protein(WHP)diet have been reported in various nutritionally high risk patient populations including-Crohn’s disease,short bowel syndrome,acute and chronic pancreatitis,cerebral palsy,cystic fibrosis,cerebrovascular accidents,human immunodeficiency virus,critically ill,and geriatrics.Collectively,the evidence from the medical literature indicates that feeding with a semi-elemental diet performs as well or better than parenteral or amino acid based diets in terms of toler-ance,digestion,and nutrient assimilation measures across various disease conditions.CONCLUSION:Based on this comprehensive review of the literature,patient populations who have difficulty digesting or absorbing standard diets may be able to achieve improved health and nutritional outcomes through the use of semi-elemental WHP diets. | Dominik D Alexander Lauren C Bylsma Laura Elkayam Douglas L Nguyen | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，2： | 3 |
| 2 | Comparative transcriptomics of Central Asian Vitis vinifera accessions reveals distinct defense strategies against powdery mildew显示文摘Grape powdery mildew(PM),caused by the biotrophic ascomycete Erysiphe necator,is a devastating fungal disease that affects most Vitis vinifera cultivars.We have previously identified a panel of V.vinifera accessions from Central Asia with partial resistance to PM that possess a Ren1-like local haplotype.In this study,we show that in addition to the typical Ren1-associated late post-penetration resistance,these accessions display a range of different levels of disease development suggesting that alternative alleles or additional genes contribute to determining the outcome of the interaction with the pathogen.To identify potential Ren1-dependent transcriptional responses and functions associated with the different levels of resistance,we sequenced and analyzed the transcriptomes of these Central Asian accessions at two time points of PM infection.Transcriptomes were compared to identify constitutive differences and PM-inducible responses that may underlie their disease resistant phenotype.Responses to E.necator in all resistant accessions were characterized by an early up-regulation of 13 genes,most encoding putative defense functions,and a late down-regulation of 32 genes,enriched in transcriptional regulators and protein kinases.Potential Ren1-dependent responses included a hotspot of co-regulated genes on chromosome 18.We also identified 81 genes whose expression levels and dynamics correlated with the phenotypic differences between the most resistant accessions‘Karadzhandahal’,DVIT3351.27,and O34-16 and the other genotypes.This study provides a first exploration of the functions associated with varying levels of partial resistance to PM in V.vinifera accessions that can be exploited as sources of genetic resistance in grape breeding programs. | Katherine C H Amrine Barbara Blanco-Ulate Summaira Riaz Dániel Pap Laura Jones Rosa Figueroa-Balderas M Andrew Walker Dario Cantu | 2015 | Horticulture Research2015，2，1： | 3 |
| 3 | Protective effects of N-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat显示文摘 | Salvatore C Emanuela M laura D | 2001 | FASEB J2001，15，： | 1 |
| 4 | Preemptive analgesia for postoperative pain control:a review显示文摘 | Laura C Guglielmo C Angelo R D | 2010 | Clin Drug invest-ing2010，30，2： | 1 |
| 5 | Proyecyive effects of N-acetylcysteine on lung injury and red blood cell modification insuced by carrageenan in the rat显示文摘 | Salvatore C Emanuela M Laura D | 2001 | FASEB J2001，15，： | 1 |
| 6 | Micromechanical adhesion force measurements between hydrate particles in hydrocarbon oils and their modifications显示文摘 | Laura E D Zachary M A Nathan C G | 2009 | Energy Fuels2009，23，： | 1 |
| 7 | Rosiglitazone, a ligand of the peroxisome proliferators-activated receptor-gamma, reduces acute pancreatitis induced by cerulean 显示文摘 | Salvatore C Barbara P Laura D | 2004 | Intensive Care Med2004，30，5： | 1 |
| 8 | Micromechanical adhesion force measurements between tetrahydrofuran hydrate particles显示文摘 | Taylor Craig J Dieker Laura E Miller Kelly T Koh C A Sloan E D | | 0，，： | 1 |
| 9 | Micromechanical adhesion force measurements between hydrate particles in hydrocarbon oils and their modifications显示文摘 | Dieker Laura E Aman Zachary M George Nathan C Sum Amadeu K Sloan E D Koh C A | | 0，，： | 1 |
| 10 | Protective effects of N- acetycysteine on lung injury and red blood cell modification induced by carrageenan in the rat 显示文摘 | Salvatore C Emanuela M Laura D | 2001 | Paseb J2001，15，7： | 1 |
| 11 | Spatially-resolved EELS analysis of antibody distribution on biofunctionalized magnetic nanoparticles显示文摘 | Raul A Laura D M Laura C Alvaro M Marcel T Valeria G Jesus M D L F Clara M Ricardo 1 | 2013 | ACS Nano2013，7，5： | 1 |
| 12 | Maize HapMap2 identifies extant variation from a genome in flux 显示文摘 | Jer-Ming Chia Chi Song Peter J Bradbury Denise Cos- tich Natalia de Leon John Doebley Robert J Elshire Brandon Gaut Laura Geller Jeffrey C Glaubitz Michael Gore Kate E Guill Jim Holland Matthew B Hufford Jinsheng Lai Meng Li Xin Liu Yanli Lu Richard Mc- Combie Rebecca Nelson Jesse Poland Boddupalli M Prasanna Tanja Pyhajarvi Tingzhao Rong Rajandeep S Sekhon Qi Sun Maud I Tenaillon Feng Tian Jun Wang Xun Xu Zhiwu Zhang Shawn M Kaeppler Jef- frey Ross-lbarra Michael D McMullen Edward S Buck- ler Gengyun Zhang Yunbi Xu Doreen Ware | 2012 | Nat Genet2012，，44： | 1 |
| 13 | Methods,results and lessons learned from process evaluation of high 5 school~based nutrition intervention显示文摘 | Kim D Frank A Laura C | 2000 | Health Educ Beha2000，27，2： | 1 |
| 14 | The effect of egg albumen on the viscoelasticity of crabsticks made from Alaska Pollock and Pacific Whiting surimi 显示文摘 | LAURA C D TOVAR C | 2009 | Food Hydrocolloids2009，24，7： | 1 |
| 15 | Added value of Virtual Touch IQ shear wave elastography in the ul- trasound assessment of breast lesions显示文摘 | Victor I Laura Maria C Ariane D | 2014 | Eur J Radi- oi2014，83，5： | 1 |
| 16 | Assessment of size reduction as a preliminary step in the production of ethanol from lignocellulosic wastes显示文摘 | Laura C López G D | 1989 | Biological Wastes1989，30，2： | 1 |
| 17 | Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat 显示文摘 | Salvatore C Emanuela M Laura D | 2001 | The FASEB Journal2001，15，： | 1 |
| 18 | Organizing Corporate Social Responsibility in Small and Large Firms: Size Matters显示文摘 | BAUMANN-PAULY D WICKERT C LAURA J | 2013 | Journal of Business Ethics2013，115，4： | 1 |
| 19 | Nurses' attitudes and practice related to hospice care显示文摘 | Laura D G Ruth M C Emily C | 2003 | J Nurs Scholarship2003，35，3： | 1 |
| 20 | The Simian T-lymphotropie/ leukemia virus from Pan paniscus belongs to the type 2 family and infects Asian macaques 显示文摘 | Laura D Adriana G Nancy C | 1997 | Journal of Virology1997，71，5： | 1 |
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