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| 1 | High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test显示文摘AIM:To assess the vitamin A status of patients with Crohn's disease(CD) by evaluating serum retinol levels and the relative dose response(RDR) test(liver retinol stores).METHODS:Vitamin A nutritional status was measured by serum retinol obtained by high performance liquid chromatography and the RDR test for evaluation of the hepatic stores.Body composition was performed by densitometry by dual-energy X-ray absorptiometry.Vitamin A dietary intake was assessed from a semiquantitative food frequency questionnaire.RESULTS:This study included 38 CD patients and 33 controls.Low serum retinol concentrations were detected in 29% of CD patients vs 15% in controls(P < 0.005).The RDR test was positive in 37% of CD patients vs 12% in controls,which indicated inadequate hepatic vitamin A stores(P < 0.005).Individuals with hypovitaminosis A had lower BMI and body fat compared with those without this deficiency.There was no association between vitamin A deficiency and its dietary intake,ileal location,presence of disease activity and prior bowel resections.CONCLUSION:Patients with CD have higher prevalence of vitamin A deficiency,as assessed by two independent methods. | Márcia Soares-Mota Tianny A Silva Luanda M Gomes Marco AS Pinto Laura MC Mendon?a Maria Lúcia F Farias Tiago Nunes Andrea Ramalho Cyrla Zaltman | 2015 | World Journal of Gastroenterology2015，21，5： | 4 |
| 2 | Transaction costs and environmental policy design显示文摘 | Laura Mc Cann | 2013 | Ecological Economics2013，，： | 1 |
| 3 | Dietary intakes associated with successful weight loss and maintenance during the Weight Loss Maintenance trial显示文摘 | Catherine MC Stephanie TB Laura DM | | 0，，12： | 1 |
| 4 | Peripoerative clinical nurse specialist role delineation : A systematic review 显示文摘 | Dennis EG Laura EN Lisa MC | 2006 | Aorn Journal2006，84，6： | 1 |
| 5 | Immortalization of Mouse Germ Line Stem Cells显示文摘 | Hofmann MC Laura BS Luis D | 2005 | Stem Cells2005，23，2： | 1 |
| 6 | Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk -deficient mice显示文摘 | Laura V Alec MC Heather EF | 2002 | J Exp Med2002，195，12： | 1 |
| 7 | Revisiting the cholinergic hypothesis in the development of Alzheimer's disease 显示文摘 | Laura A Craig Nancy S Hong Robert J Mc Donald | 2011 | Neurosci B~obehav Rev2011，35，6： | 1 |
| 8 | Culturable and nonculturable fractions of bacterial populations in sediments of a South Carolina stream显示文摘 | Mc Namara Christopher J Lemke Michael J Leff Laura G | 2002 | Hydrobiologia2002，482，： | 1 |
| 9 | Added value of Virtual Touch IQ shear wave elastographyin the ultrasound assessment of breast le- sions显示文摘 | Victor I Laura MC Ariane D | 2014 | European Journal of Radiology2014，83，5： | 1 |
| 10 | Review of control strategies for robotic movement training after neurologic injury 显示文摘 | Laura MC David J | 2009 | J Neuroeng Re- habil2009，6，1： | 1 |
| 11 | Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk -deficient mice显示文摘 | Laura V Alec MC Heather EF | 2002 | J Exp Med2002，195，12： | 1 |
| 12 | Therapeutic hypothermia in a late preterm infant显示文摘 | Laura F Mori A Tataranno ML Muraca MC Rodriquez DC Giomi S | 2012 | J Matern Fetal Neonatal Med2012，，： | 1 |
| 13 | VNTR analysis reveals unexpected genetic diversity within Mycoplasma agalactiae,the main causative agent of contagious agalactia显示文摘 | Laura Mc Auliffe Colin P Churchward Guido LORIA | 2008 | BMC Microbiology2008，8，： | 1 |
| 14 | Retrospective analysis of selective lymphadenectomy in appareJ-t early-stage endometrial cancer 显示文摘 | Janiel MC Laura JH Brian C | 2005 | J Clin Oncol2005，23，16： | 1 |
| 15 | The efficacy of different models ofsmoke-free laws in reducing exposure to second-hand smoke: a muhi-countrycomparison 显示文摘 | Mark W Laura MC Zubair K | 2013 | Health Policy2013，110，23： | 1 |
| 16 | Rituximab therapy for chonic and refractory immune thrombocytopenic purpura:a longterm follow-up analysis显示文摘 | Jaime GC Abraham MC Laura MC | 2007 | Ann Hematol2007，86，： | 1 |
| 17 | Peripoerative clinical nurse specialist role delineation:A systematic review显示文摘 | Denn is EG Laura EN Lisa MC | 2006 | Aom J2006，84，6： | 1 |
| 18 | 泥浆录井技术新进展(一)显示文摘数十年来,地面采集的样品和计量结果为录井人员提供了洞察钻头端面条件的重要信息。通过录井采集的信息使作业者提前了解油藏潜力,甚至提前预防地层压力问题。而新型采样和分析技术,以及地面传感器设计和监测系统的进步,使录井科学正以新的面貌迈进21世纪。 | Peter Ablard Chris Bell David Cook Ivan Fornasier Jean-Pierre Poyet Kevin Fielding Laura Lawton George Haines Mark A. Herkommer Kevin Mc Carthy Maja Radakovic Lawrence Umar | 2014 | 国外测井技术2014，，2： | 0 |
| 19 | Burden of nonalcoholic fatty liver disease and advanced fibrosis in a Texas Hispanic community cohort显示文摘AIM: To investigate the potential burden of nonalcoholic steatohepatitis(NASH) and advanced fibrosis in a hispanic community.METHODS: Four hundred and forty two participants with available ultrasonography data from the Cameron County Hispanic Cohort were included in this study. Each participant completed a comprehensive questionnaire regarding basic demographic information, medical history, medication use, and social and family history including alcohol use. Values of the nonalcoholic fatty liver disease fibrosis score(NFS), FIB4 index, BARD score, and Aspartate aminotransferase to Platelet Ratio Index(APRI) were computed using the blood samples collected within 6 mo of liver ultrasonography from each participant. Hepatic steatosis was determined by ultrasonography. As part of univariable analysis, for continuous variables, comparisons among groups were performed with student-t test, one way analysis of variance, and Mann-Whitney test. Pearson χ2 and the Fisher exact test are used to assess differences in categorical variables. For multivariable analyses, logistic regression analyses were performed to identify characteristics associated with hepatic steatosis. All reported P values are based two-sided tests, and a P value of less than 0.05 was considered to indicate statistical significance.RESULTS: The mean age and body mass index(BMI) of the study participants were 49.1 years and 31.3 kg/m2, respectively. Among them, 65.6% were females, 52% had hepatic steatosis, 49.5% had metabolic syndrome, and 29% had elevated aminotransferases. Based on established cut-offs for diagnostic panels, between 17%-63% of the entire cohort was predicted to have NASH with indeterminate or advanced fibrosis. Participants with hepatic steatosis had significantly higher BMI(32.9 ± 5.6 kg/m2 vs 29.6 ± 6.1 kg/m2, P < 0.001) and higher prevalence rates of elevation of ALT(42.2% vs 14.6%, P < 0.001), elevation of aspartate aminotransferase(38.7% vs 18.9%, P < 0.001), and metabolic syndrome(64.8% vs 33%, P < 0.001) than those without hepatic steatosis. The NFS scores(P = 0.002) and the APRI scores(P = 0.002) were significantly higher in those with steatosis but the scores of the FIB4 index and BARD were similar between the two groups. After adjusting for age, gender and BMI, elevated transaminases, metabolic syndrome and its components, intermediate NFS and APRI scores were associated hepatic steatosis in multivariable analysis. CONCLUSION: The burden of NASH and advanced fibrosis in the Hispanic community in South Texas may be more substantial than predicted from referral clinic studies. | Jen-Jung Pan Susan P Fisher-Hoch Chaoru Chen Ariel E Feldstein Joseph B Mc Cormick Mohammad H Rahbar Laura Beretta Michael B Fallon | 2015 | World Journal of Hepatology2015，7，11： | 0 |
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