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| 1 | Gut-microbiome-brain axis:the crosstalk between the vagus nerve,alpha-synuclein and the brain in Parkinson's disease显示文摘This critical review of the literature shows that there is a close link between the microbiome,the gut,and the brain in Parkinson's disease.The vagus nerve,the main component of the parasympathetic nervous system,is involved in the regulation of immune response,digestion,heart rate,and control of mood.It can detect microbiota metabolites through its afferents,transferring this gut information to the central nervous system.Preclinical and clinical studies have shown the important role played by the gut microbiome and gut-related factors in disease development and progression,as well as treatment responses.These findings suggest that the gut microbiome may be a valuable target for new therapeutic strategies for Parkinson's disease.More studies are needed to better understand the underlying biology and how this axis can be modulated for the patient's benefit. | Júlio César Claudino dos Santos Leandro Freitas Oliveira Felipe Micelli Noleto Camilla Teixeira Pinheiro Gusmão Gerly Anne de Castro Brito Glauce Socorro de Barros Viana | 2023 | Neural Regeneration Research2023，18，12： | 2 |
| 2 | Learning and Optimization Using the Clonal Selection Principle 显示文摘 | Leandro N Fernando J | 2002 | IEEE Transactions on Evolutionary Computation2002，6，3： | 1 |
| 3 | Comparison of 1D/1D and 1D/2D coupled(sewer/surface)hydraulic models for urban flood simulation 显示文摘 | Leandro J Chen A Djordjevic S | 2009 | J Hydraul Eng2009，135，6： | 1 |
| 4 | The effect of colchicine on liver function tests and hepatic fibrosis in patients with chronic active hepatitis:a study of 3 cases(author's transl)显示文摘 | Leandro P Ade O e Silva A BrandSo J F Saldanha L B Pontes J F | 2013 | Arquivos de Gastroenterologia2013，15，3： | 1 |
| 5 | Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal - cell carcinoma treated with first - line sunitinib : a muhicentre, observational, prospective study 显示文摘 | GARCIA - DONAS J ESTEBAN E LEANDRO - GARCIA L J | 2011 | Lancet Oncol2011，12，12： | 1 |
| 6 | Randomised controlled trials of ursodeoxycholic - acid therapy for primary biliary cirrhosis : a meta-analysis 显示文摘 | GOULIS J LEANDRO G BURROUGHS AK | 1999 | Lancet1999，354，： | 1 |
| 7 | Adsorption of chromium (VI) ion from aqueous solution by succinylated mercerized cellulose functionalized with quaternary ammonium groups显示文摘 | Leandro Vinícius Alves Gurgel Júlio César Perin de Melo Jorge Carvalho de Lena Laurent Frédéric Gil | 2009 | Bioresource Technology2009，，13： | 1 |
| 8 | The expression in Saccharomyces cerevisiae of a glucose/xylose symporter from Candida intermedia is affected by the presence of a glucose/ xyose facilitor 显示文摘 | Leandro M J Spencer-Martins I Goncalves P | 2008 | Microbiology2008，154，： | 1 |
| 9 | Hexose and pentose transport in ascomycetous yeasts:an overview显示文摘 | Leandro M J Fonseca C Goncalves P | | 0，，04： | 1 |
| 10 | Learning and Optimization Using the Clone Selection Principle显示文摘 | Leandro N De Castro Fernando J Von Zuben | 2002 | lEE Transactions on Evolutionary Computation Special Issue one Artificial Immune Suystems2002，6，3： | 1 |
| 11 | Learning and optimization using clonal selection principle显示文摘 | LEANDRO Nunes de Castro FERNANDO J Von Zuben | 2001 | IEEE Transactions on Evolutionary Computation Special Issue on Artificial Immune Systems2001，6，3： | 1 |
| 12 | B cell depletion thera- py in systemic lupus erythematosus: long-term follow-up and predictors of response显示文摘 | Ng K P Cambridge G Leandro M J | 2007 | Ann Rheum Dis2007，66，9： | 1 |
| 13 | Learning and optimization using the clonal selection principle显示文摘 | LEANDRO N D C FERNANDO J V Z | 2002 | IEEE Trans on Evolutionary Computation2002，6，3： | 1 |
| 14 | Retinal vessel segmentation using the 2-D Gabor wavelet and supervised classification显示文摘 | Soares J V B Leandro J J G Cesar R M | 2006 | IEEE Transactions on Medical Imaging2006，25，9： | 1 |
| 15 | B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients 显示文摘 | LEANDRO M J CAMBRIDGE G EDWARDS J C | 2005 | Rheumatology2005，44，12： | 1 |
| 16 | Learning and optimization using the clonal selection principle显示文摘 | Leandro N de Castro Fernando J Von Zuben | 2002 | IEEE Trans on Evolutionary Computation Special Issue on Artificial Immune Systems2002，6，3： | 1 |
| 17 | Determination of priority pesticides in baby foods by gas chromatography tandem quadrupole mass spectrometry显示文摘 | LEANDRO C C FUSSELL R J KEELY B J | 2005 | Journal of chromatography A2005，1085，2： | 1 |
| 18 | Expression of heat shock protein in broiler embryo tissues after acute cold or heat stress显示文摘 | Leandro N S Gonzales E Ferro J A | 2004 | Mol Reprod Dev2004，67，2： | 1 |
| 19 | B cell depletion therapy in systemic lupus erythematosus: long-term follow-up and predictors of response显示文摘 | NG K P CAMBRIDGE G LEANDRO M J | 2007 | Ann Rheum Dis2007，66，9： | 1 |
| 20 | Ultra-performance liquid chromatography for the determination of pesticide residues in foods by tandem quadrupole mass spectrometry with polarity switching显示文摘 | LEANDRO C C HANCOCK P FUSSELL R J | 2007 | J Chromatogr: A2007，1144，2： | 1 |
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