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17篇 您的检索式:作者名="Lee Adam F"
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1Reproducibility of thrombus volume quantification in multicenter computed tomography pulmonary angiography studies显示文摘AIM To evaluate reproducibility of pulmonary embolism(PE) clot volume quantification using computed tomography pulmonary angiogram(CTPA) in a multicenter setting.METHODS This study was performed using anonymized data in conformance with HIPAA and IRB Regulations(March 2015-November 2016). Anonymized CTPA data was acquired from 23 scanners from 18 imaging centers using each site's standard PE protocol. Two independent analysts measured PE volumes using a semi-automated region-growing algorithm on an FDA-approved image analysis platform. Total thrombus volume(TTV) was calculated per patient as the primary endpoint. Secondary endpoints were individual thrombus volume(ITV), Qanadli score and modified Qanadli score per patient. Inter-and intra-observer reproducibility were assessed using intra-class correlation coefficient(ICC) and BlandAltman analysis. RESULTS Analyst 1 found 72 emboli in the 23 patients with a mean number of emboli of 3.13 per patient with a range of 0-11 emboli per patient. The clot volumes ranged from 0.0041-47.34 cm3(mean +/-SD, 5.93 +/-10.15 cm3). On the second read, analyst 1 found the same number and distribution of emboli with a range of volumes for read 2 from 0.0041 – 45.52 cm3(mean +/-SD, 5.42 +/-9.53 cm3). Analyst 2 found 73 emboli in the 23 patients with a mean number of emboli of 3.17 per patient with a range of 0-11 emboli per patient. The clot volumes ranged from 0.00459-46.29 cm3(mean +/-SD, 5.91 +/-10.06 cm3). Inter-and intraobserver variability measurements indicated excellent reproducibility of the semi-automated method for quantifying PE volume burden. ICC for all endpoints was greater than 0.95 for inter-and intra-observer analysis. Bland-Altman analysis indicated no significant biases.CONCLUSION Semi-automated region growing algorithm for quantifying PE is reproducible using data from multiple scanners and is a suitable method for image analysis in multicenter clinical trials.Audrey E Kaufman Alison N Pruzan Ching Hsu Sarayu Ramachandran Adam Jacobi Indravadan Patel Lee Schwocho Michele F Mercuri Zahi A Fayad Venkatesh Mani 2018World Journal of Radiology2018,10,10:3
2Vasopressin: a new target for the treatment of heart failure显示文摘Craig R Lee Michael L Watkins J.Herbert Patterson Wendy Gattis Christopher M O'Connor Mihai Gheorghiade Kirkwood F Adams 2003American Heart Journal2003,,1:1
3Bax crystal structures reveal how BH3domains activate Bax and nucleate its oligomerization to induce apoptosis显示文摘Czabotar P E Westphal D Dewson G Ma S Hockings C Fairlie W D Lee E F Yao S Robin A Y Smith B J Huang D C Kluck R M Adams J M Colman P M 2013Cell2013,152,3:1
4Zirconium phosphate supported tungsten oxide solid acid catalysts for the esterification of palmitic acid显示文摘 Adapa Sridhar Adam F Lee 2006Green Chem2006,8,:1
5In-situ XPS study on the reducibility of Pd-promoted Cu/CeO2 catalysts for the oxygen-assisted water-gas-shift reaction显示文摘Fox Elise B Lee Adam F Wilson Karen 2008Topics in Catalysis2008,49,12:1
6Structure -reactivity correlations in MgAl hydrotalcite catalysts for biodiesel synthesis 显示文摘David G Cantrell Lisa J Gillie Adam F Lee 2005Applied Catalysis A : General2005,287,:1
7Continuous atmospheric plasma fluorination of carbon fibres显示文摘Kingsley K C Ho Adam F Lee Steven L 2008Composites:Part A2008,39,:1
8Surrogate end points in heart failure显示文摘Lee C R Adams K F patterson J H 2002Ann Pharmaeother2002,36,3:1
9Structure - reactivity correlations in MgAI hydrotalcite catalysts for biodiesel synthesis 显示文摘DAVID G CZNTRELL LISA J GILLIE ADAM F LEE 2005Applied Catalysis A : General2005,287,:1
10Structure-reactivity correlations in sulphated-zirconia catalysts for the isomerisation of α-pinene 显示文摘Ecormier Muriel A Wilson Karen Lee Adam F 2003Journal of Catalysis2003,215,:1
11Small worlds and regional innovation 显示文摘Lee F Charles K I Adam I J 2007Organization Science2007,18,6:1
12Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence显示文摘ADAMS M D KERLAVAGE A R FLEISCHMANN R D FULDNER R A BULT C J LEE N H KIRKNESS E F WEINSTOCK K G GOCAYNE J D WHITE O 1995Nature1995,377,6547:1
13Physicochemical properties of Pt-SO4/Al2O3 alkane oxidation catalysts 显示文摘Gawthrope David E Lee Adam F Wilson Karen 2004Phys Chem Chem Phys2004,,6:1
14Supportmediated alkane activation over Pt-SO4/Al2O3 catalysts显示文摘Gawthrope David E Lee Adam F Wilson Karen 2004Catalysis Letters2004,94,12:1
15Structure- reactivity correlations in Mg- Al hydrotaleite catalysts for biediesd synthesis显示文摘David G CanneR Lisa J Gillie Adam F Lee Karen Wilson 2005Applied Catalysis2005,287,:1
16Vasopressin: a new target for the treatment of heart failure显示文摘Craig R Lee Michael L Watkins J.Herbert Patterson Wendy Gattis Christopher M O’Connor Mihai Gheorghiade Kirkwood F Adams 2003American Heart Journal2003,,1:1
17Electroeoating of carbon fibres: A route for interface control in carbon fibre reinforced poly methyhnethacrylate显示文摘Alexander Bismarck Adam F Lee a Sezai sarac 2005Composites Science and Technology2005,65,:1
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