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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014,5,2: | 5 |
| 2 | Enhanced cellular immunity to hepatitis C virus nonstructural proteins by codelivery of granulocyte macrophage-colony stimulating fact or gene in intramuscular DNA immunization显示文摘 | Cho J H Lee S W Sung Y C | 1999 | Vaccine1999,17,910: | 2 |
| 3 | Optimal induction of hepatitis C virus envelope-specific immunity by bicistronic plasmid DNA inoculation with the granulocyte-macrophage-colony stimulating factor gene显示文摘 | Lee S W Cho J H Sung Y C | 1998 | J Virol1998,72,10: | 2 |
| 4 | 血根碱对肉鸡生长性能、相对器官重量、盲肠菌群、血清胆固醇水平以及肉品质的影响显示文摘研究旨在探索日粮添加血根碱(SGV)对肉鸡生长性能、相对器官重量、盲肠菌群、血清胆固醇水平和腿肌丙二醛含量的影响。选用840日龄雄性肉鸡(罗斯品种)饲养于28个稻草垫上,随机分为4个处理:玉米-豆粕型基础对照日粮、基础日粮中添加卑霉素10 ppm作为生长促进剂(AGP)、基础日粮中添加SGV 20 ppm(SGV20)和50 ppm(SGV50)。与饲喂基础日粮的肉鸡相比,基础日粮中添加AGP组、SGV20组和SGV50组的肉鸡最终体重(BW)、日增重、饲料转化率(FCR)显著改善(P<0.05)。与对照组相比,SGV20喂养组的肉鸡相对空肠重量显著降低(P<0.05),所有添加SGV组肉鸡相对空肠或回肠长度显著升高(P<0.05)。SGV20组较对照组肉鸡肠道菌群有所改变,尤其是盲肠乳酸菌数增加,但AGP组无改变。SGV20组或SGV50组肉鸡的总胆固醇水平较对照组显著降低(P<0.05),控制饮食物显著降低(P<0.05)。添加SGV后,作为脂质过氧化反应指示剂的腿肌丙二醛含量显著降低(P<0.05)。研究表明,在肉鸡日粮中补充SGV 20或50 ppm可以提高肉鸡生长性能,改变多种生物和生理参数,如相对器官重量、血清胆固醇水平、肠道菌群和肉品质。 | Lee K W Kim J S Oh S T Kang C W An B K | 2015 | 饲料博览2015,0,3: | 2 |
| 5 | Brittle elastoplastic damage constitutive model for jointed rockmass and computation concerning bolt-reinforcement显示文摘 | Zhu W Zhang Q Li S Lee C F | 2003 | International Journal of Damage Mechanics2003,12,: | 2 |
| 6 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017,25,5: | 2 |
| 7 | 中草药对断奶仔猪中性粒细胞免疫活性和小肠形态学的影响显示文摘试验旨在评估由人参、薯蓣、白术、甘草、红枣和桔梗组成的中草药(CMH)对断奶仔猪生产性能、肠道形态学和免疫活性的影响。将240头断奶仔猪随机分为4个日粮处理组:负对照组(基础日粮),CMH0.1%、CMH0.3%、抗生素0.114%(金霉素钙复合物、磺胺噻唑、青霉素普鲁卡因G)添加组,试验期28d。结果表明,试验期前14d,两个CMH添加组比对照组(CT组)有较佳的增重和饲料增重比。与其他组比较,在试验前10d,CMH0.3%组的腹泻评分显著下降。与对照组比较,CMH添加组有较高的绒毛高度,回肠食糜乳酸菌计数增加,大肠菌群数下降。在试验第7天,CMH添加组的多形核白细胞(PMNs)活性,包括突发性呼吸和沙门氏菌杀灭能力显著提高。添加CMH和抗生素可提高断奶仔猪日粮干物质、粗蛋白质和总能的养分消化率。结果表明,日粮添加CMH可改善肠道形态学和PMNs的免疫活性,因而提高断奶仔猪的养分消化率,降低腹泻频率。 | Huang C W Lee T T Shih Y C Yu B 张树金 | 2012 | 饲料博览2012,,9: | 2 |
| 8 | An efficient assumed strain element model with 6 dof per node for geometrically nonlinear shells显示文摘 | Park H C Cho C Lee S W | 1995 | Inter J Numer Methods Engrg1995,38,: | 2 |
| 9 | Comparison of the filtration characteristics between attached and suspended growth microorganisms in submerged membrane bioreactor显示文摘 | Lee J Ahn W Y Lee C H | 2001 | Wat Res2001,35,10: | 2 |
| 10 | Involvement of p27kip1 in ceramide-mediated apoptosis in HL-60 cells 显示文摘 | Kim W H Ghil K C Lee J H | 2000 | Cancer Letter2000,151,: | 2 |
| 11 | The effect of pre-irradiation dose intense CHOP on anthracyline resistance in localized nasal NK/ T-cell lymphoma显示文摘 | Lee S H Ahn Y C Kim W S | 2006 | Haematologica2006,91,3: | 1 |
| 12 | Determination of total, soluble, and insoluble dietary fibre in foods-enzymaticgravimetric methods,MES-TRIR buffer collaborative study显示文摘 | Lee S C Prosky L De Vries J W | 1992 | AOAC Int1992,75,: | 1 |
| 13 | The potential role of resistin in atherogenesis 显示文摘 | BURNETT M S LEE C W KINNAIRD T D | 2005 | Atherosclerosis2005,182,: | 1 |
| 14 | Evaluation of seismic performance of multistory building structures based on the equivalent responses 显示文摘 | LEE D G CHOI W H CHEONG M C | 2006 | Engineering Structures2006,28,6: | 1 |
| 15 | Dragged surge motion of tension leg platforms and strained elastic tethers显示文摘 | Lee H H Wang P W Lee C P | 1999 | Ocean Engineering1999,26,: | 1 |
| 16 | Next generation/dynamic spectrum access/cognitive radio wireless networks:A survey 显示文摘 | AKYILDIZ I F LEE W Y VURAN M C | 2006 | Comput Netw2006,50,13: | 1 |
| 17 | Modeling of fugitive dust emission for construction sand and gravel processing plant显示文摘 | Lee C H Tang L W Chang C T | 2001 | Environmental Science and Technology2001,35,: | 1 |
| 18 | Surface characterization in ultra-precision machining of Al/SiC metal matrix composites using data dependent systems analysis显示文摘 | CHEUNG C F CHAN K C LEE W B | 2003 | Journal of Materials Processing Technology2003,140,: | 1 |
| 19 | Antioxidant capacity of phenolic phytochemicals from various cultivars of plums显示文摘 | KIM D O JEONG S W LEE C Y | 2003 | Food Chem2003,81,: | 1 |
| 20 | Novel alloys improve the electrochemical behavior of zinc anodes for zinc/air battery 显示文摘 | Lee C W Sathiyanarayanan K Eom S W Yun M S | 2006 | Journal of Power Sources2006,160,: | 1 |