|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Risk stratification in symptomatic intracranial atherosclerotic disease with conventional vascular risk factors and cerebral haemodynamics显示文摘Background and purpose Symptomatic intracranial atherosclerotic stenosis(sICAS)is associated with a considerable risk of recurrent stroke despite contemporarily optimal medical treatment.Severity of luminal stenosis in sICAS and its haemodynamic significance quantified with computational fluid dynamics(CFD)models were associated with the risk of stroke recurrence.We aimed to develop and compare stroke risk prediction nomograms in sICAS,based on vascular risk factors and these metrics.Methods Patients with 50%-99%sICAS confirmed in CT angiography(CTA)were enrolled.Conventional vascular risk factors were collected.Severity of luminal stenosis in sICAS was dichotomised as moderate(50%-69%)and severe(70%-99%).Translesional pressure ratio(PR)and wall shear stress ratio(WSSR)were quantified via CTA-based CFD modelling;the haemodynamic status of sICAS was classified as normal(normal PR&WSSR),intermediate(otherwise)and abnormal(abnormal PR&WSSR).All patients received guideline-recommended medical treatment.We developed and compared performance of nomograms composed of these variables and independent predictors identified in multivariate logistic regression,in predicting the primary outcome,recurrent ischaemic stroke in the same territory(SIT)within 1 year.Results Among 245 sICAS patients,20(8.2%)had SIT.The D2H2A nomogram,incorporating diabetes,dyslipidaemia,haemodynamic status of sICAS,hypertension and age≥50 years,showed good calibration(P for Hosmer-Lemeshow test=0.560)and discrimination(C-statistic 0.73,95%CI 0.60 to 0.85).It also had better performance in risk reclassification and provided larger net benefits in decision curve analysis,compared with nomograms composed of conventional vascular risk factors only,and plus the severity of luminal stenosis in sICAS.Sensitivity analysis in patients with anterior-circulation sICAS showed similar results.Conclusions The D2H2A nomogram,incorporating conventional vascular risk factors and the haemodynamic significance of sICAS as assessed in CFD models,could be a useful tool to stratify sICAS patients for the risk of recurrent stroke under contemporarily optimal medical treatment. | Xuan Tian Hui Fang Linfang Lan Hing Lung Ip Jill Abrigo Haipeng Liu Lina Zheng Florence S Y Fan Sze Ho Ma Bonaventure Ip Bo Song Yuming Xu Jingwei Li Bing Zhang Yun Xu Yannie O Y Soo Vincent Mok Ka Sing Wong Thomas W Leung Xinyi Leng | 2023 | Stroke & Vascular Neurology2023，8，1： | 2 |
| 2 | Characteristics of MnO2 catalytic ozonation of sulfosalicylic acid and propionic acid in water显示文摘 | Tong S P Liu W P Leng W H | 2003 | Chemosphere2003，50，： | 1 |
| 3 | Immunological study of hal domain of he- magglutinin of influenza hSnl virus 显示文摘 | Chiu F F Venkatesan N Wu C R Chou A H Chen H W Lian S P Liu SJ Huang C C Lian W C Chong P Leng C H | 2009 | Biochemical Biophys ResCommun2009，383，1： | 1 |
| 4 | Lp-mixed affine surface area显示文摘 | Wang W D Leng G S | 2007 | J Math Anal Appl2007，54，： | 1 |
| 5 | Characteristics of MnO2 catalytic ozonation of sulfosalicylic acid and propionic acid in water显示文摘 | Liu W P Leng W H | 2003 | Chemosphere2003，50，： | 1 |
| 6 | Characteristics of MnO2 catalytic ozonation of sulfosalicylic acid and propi-onic acid in water 显示文摘 | Tong S P Liu W P Leng W H | 2003 | Chemosphere2003，50，10： | 1 |
| 7 | Kinetics of photocatalytic degradation of aniline in water over TiO2 supported on porous nickel显示文摘 | LENG W H LIU H CHENG S A ZHANG Z ZHANG J Q CAO C N | 2000 | J Photochem Photobiol A:Chem2000，131，： | 1 |
| 8 | Electromechanical stability of dielectric elastomer显示文摘 | LENG J S LIU L W LIU Y J | | Applied Physics Letters0，4，21： | 1 |
| 9 | Kinetics of photocatalytic degradation of aniline in water over TiO2 supported on porous nickel显示文摘 | Leng W H Liu H Cheng S A | 2000 | Journal of Photochemistry and Photobiology A:Chemistry2000，，131： | 1 |
| 10 | Kinetics of photocatalytic degradation of aniline in water over TiO2 supported on porous nickel显示文摘 | Lin H Chang S | 2000 | J Photochem Photobiol A: Chem2000，131，： | 1 |
| 11 | Fiber reinforcement and fracture resistance of PC/PBT/LCP ternary in situ composite显示文摘 | Mai Y W Leng Y | 1998 | Polym Eng Sci1998，38，1： | 1 |
| 12 | Kinetics of photocatalytic degradation of aniline in water over TiO2 supported on porous nickel显示文摘 | LENG W H LIU H CHENG S A | 2000 | J Photochem Photobiol A:Chem2000，131，13： | 1 |
| 13 | Lp-dual mixed quermassintegrals显示文摘 | Wang W D Leng G S | 2005 | Indian J Pure Appl Mat2005，36，4： | 1 |
| 14 | Optimization of superstructured fiber Bragg gratings for microwave photonic filters response显示文摘 | Leng J S Zhang W Williams J A R | 2004 | IEEE Photonics Technology Letters2004，16，7： | 1 |
| 15 | Study on the activation of styrene-based shape memory polymer by medium-infrared laser light显示文摘 | Leng J S Zhang D W Liu Y J | 2010 | Appl Phys Lett2010，96，11： | 1 |
| 16 | Characteristics of MnO2 catalytic ozonation of sulfosalicylic acid and propionic acid in water显示文摘 | Liu W P Leng W H | 2003 | Chemosphere2003，50，10： | 1 |
| 17 | Kinetics of photo - cat- alytic degradation of aniline in water over TiO2 supported onporous nick- el显示文摘 | LENG W H CHENG S A ZHANG J Q | 1992 | Photochem Photobiol A : Chem1992，69，： | 1 |
| 18 | Analysis of the relationship between CTOD toughness and micro mechanism of marine steel weht joints显示文摘 | Leng S W Miao Zm Qiu F X | 2011 | Applied Mechanics and Materials2011，117，10： | 1 |
| 19 | Reconstruction of Holocene monsoon history from the Pearl River estuary, southern Chins, using diatoms and carbon isotope ratios显示文摘 | ZONG Y Q LOYD J M LENG M J YIM W S HUANG G Q | 2006 | The Holocene2006，16，： | 1 |
| 20 | Bone mesenchymal stem cellsfor gene transfer of NGF to the adult rat brain:rescue the NG-FR p75 positive neurons from fimbria-fornix lesion-induceddegeneration显示文摘 | Leng S He J Fan W | 2008 | Neurosci Lett2008，448，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员