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| 1 | Juvenile hemochromatosis:HAMP mutation and severe iron overload treated with phlebotomies and deferasirox显示文摘Juvenile hemochromatosis(JH) is a rare condition classified as an autosomal recessive disorder that leads to severe iron absorption. JH usually affects people under the age of 30 and presents symptoms such as chronic liver damage,hypogonadotropic hypogonadism,cardiac diseases and endocrine dysfunctions. The present case reports a 29-year-old Brazilian woman with JH condition due to HAMP mutation(g.47G>A),treated with phlebotomies and deferasirox. She presented symptoms such as weakness,skin hyperpigmentation,joint pain in the shoulders and hands and amenorrhea. First laboratory tests showed altered biochemical parameters [serum ferritin(SF): 5696 ng/mL,transferrin saturation(TS): 85%]. After sessions of phlebotomies(450 mL every 15 d),the patient presented partial symptomatic improvements and biochemical parameters(SF: 1000 ng/mL,Hb: 11 g/dL). One year later,deferasirox(15 mg/kg per day) was introduced to the treatment,and the patient showed total symptomatic improvement,with significant clearing of the skin,SF: 169 ng/mL,and TS: 50%. Furthermore,after the combined deferasirox-phlebotomy therapy,magnetic resonance imaging measurements revealed normalized level for liver iron(30 μmol/g; reference value < 36 μmol/g). In conclusion,combined deferasirox-phlebotomy treatment was able to normalize iron levels and improve symptoms. | Manuel A Lescano Letícia C Tavares Paulo C J L Santos | 2017 | World Journal of Clinical Cases2017，5，10： | 2 |
| 2 | Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study显示文摘 | Douglas S Berkman Andres G Lescano Robert H Gilman Sonia L Lopez Maureen M Black | 2002 | The Lancet2002，，9306： | 1 |
| 3 | Change in viability of maize during high-temperature drying显示文摘 | Lescano C L Tyrrell D E | | 0，，： | 1 |
| 4 | Electrochemical oxidation of ammonia in alkaline solutions: its application to an amperometric sensor 显示文摘 | Lopez de Mishima B A Lescano D Holgado T M | 1998 | Electrochimica Acts1998，43，： | 1 |
| 5 | Electrochemical oxidation of ammonia in alkaline solutions: its application to an amperometric sensor显示文摘 | de Mishima B A Lopez Lescano D Molina Holgado T | 1998 | Electrochimica Acta1998，43，： | 1 |
| 6 | Effectiveness of new spectral tools in the anomaly detection of rolling element bearings 显示文摘 | Pineyro J Klempnow A Lescano V | 2000 | Journal of Alloys and Compounds2000，3，10： | 1 |
| 7 | New con- straints on the Jurassic-Cretaceous boundary in the High An- des using high-precision U-Pb data显示文摘 | Vennari V V Lescano M Naipauer M | 2014 | Gondwana Research2014，26，： | 1 |
| 8 | Extension of mushroom(Agaricus bisporus)shelf life by gamma radiation显示文摘 | LESCANO G | 1994 | Postharvest Biology and Technology1994，4，3： | 1 |
| 9 | Effectiveness of new, spectral tools in the anomaly detection of rolling element bearings显示文摘 | J Pineyro KlemPnow V Lescano | 2000 | Journal of Alloy Sand Compounds2000，510，1： | 1 |
| 10 | The value of the World Conferences on Research Integrity:perspectives from Peru显示文摘“The World Conferences on Research Integrity(WCRIs),six to date,were initiated at a time when researchers in various countries were at quite different stages in their thinking about research integrity.Over the course of the past decade,the global conferences have reflected and documented significant changes in the way research integrity is viewed and supported”[1]. | Mariela DejoVásquez Roxana Lescano Juan Guillermo PérezCarreño | 2021 | Forensic Sciences Research2021，6，3： | 1 |
| 11 | The conflict between agricultural expansion and priority conservation areas: Making the right decisions before it is too late显示文摘 | Nori J Lescano J Illoldi-Rangel C | 2013 | Biological Conservation2013，159，3： | 1 |
| 12 | HUMAN TOXOCARIASIS: CONTRIBUTION BY BRAZILIAN RESEARCHERS显示文摘 | Chieffi Pedro Paulo dos Santos Sérgio Vieira de Queiroz Maisa Leite Lescano Susana A Zevallos | 2009 | Revista do Instituto de Medicina Tropical de S茫o Paulo2009，，6： | 1 |
| 13 | Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study显示文摘 | Berkman DS Lescano AG Gilman RH | 2002 | Lencot2002，359，： | 1 |
| 14 | Cultural factors and family-based HIV prevention intervention for Latino youth 显示文摘 | Lescano C M Brown L K Raffaelli M | 2009 | J Pediatr Psychol2009，34，10： | 1 |
| 15 | Extension of mushroom (Agaricus bisporus) shelf life by gamma radiation显示文摘 | LESCANO G | 1994 | Postharvest Biology and Technology1994，4，3： | 1 |
| 16 | Perilesional brain oedema and seizure activity in patients with calcified neurocysticercosis, a prospective cohort and nested case-control study 显示文摘 | Nash TE Pretell EJ Lescano AG | 2008 | Lancet Neurol2008，7，12： | 1 |
| 17 | Effect of the suctionswallowing action on orofacial development and growth显示文摘 | Lescano de Ferrer A Varela de Villalba TB | 2006 | Rev Fac Cien Med Univ Nac Cordoba2006，63，2： | 1 |
| 18 | Effectiveness of new spectral tools in the anomaly detection of rolling element bearings显示文摘 | Pineyro J Klempnow A Lescano V | 2000 | Journal of Alloys and Compounds2000，3，10： | 1 |
| 19 | The conflict between agricultural expansion and priority conservation areas: Making the right decisions before it is too late显示文摘 | Nori J Lescano J Illoldi-Rangel C | 2013 | Biological Conservation2013，159，3： | 1 |
| 20 | Extension of mushroom (Agaricus)shelf life by gamma radiation显示文摘 | LESCANO G | 1994 | Postharvest Bioligy and Rechnology1994，4，3： | 1 |
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