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7篇 您的检索式：作者名="Levêque"

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		题名	作者	年代	出处	被引量
	1	Off-label use of targeted therapies in oncology显示文摘Off-label use is defined by the prescription of a marketed drug outside the conditions described in the summary of product characteristics.In oncology,off-label prescribing of targeted therapies may occur in patients with other tumor types expressing the same target.Agents associated to phenotypic approaches such as therapies against the tumoral vasculature(anti-angiogenic drugs) and new immunotherapies(checkpoint inhibitors) also carry the potential of alternative indications or combinations.Off-label use of targeted therapies is little documented and appears to be in the same range than that regarding older drugs with wide variations among agents.When compared with older agents,off-label use of targeted therapies is probably more rational through tumoral genotyping but is faced with a limited clinical support,reimbursement challenges related to the very high pricing and the cost of genotyping or molecular profiling,when applicable.	Dominique Levêque	2016	World Journal of Clinical Oncology2016，7，2：	0
	2	Cervical length in asymptomatic twin pregnancies:prospective multicenter comparison of predictive indicators显示文摘	Levêque C Vayssière C Favre R	2014	J Matern Fetal Neonatal Med2014，27，5：	1
	3	Clinical pharmacokinetics of voriconazole显示文摘	Levêque D Nivoix Y Jehl F	2006	Int J Antimicrob Agents2006，27，4：	1
	4	Immunity of human epithelial ovarian carcinoma:the paradigm of immune suppression in cancer显示文摘	Lavoué V Thédrez A Levêque J	2013	J Transl Med2013，11，1：	1
	5	Main outcomes of a newborn hearing screening program in Belgium over six years显示文摘	Vos B Lagasse R Levêque A	2014	Int J Pediatr Otorhinolaryngol2014，78，9：	1
	6	Review of therapeutic drug monitoring of anticancer drugs part two – Targeted therapies显示文摘	Nicolas Widmer Christophe Bardin Etienne Chatelut Angelo Paci Jos Beijnen Dominique Levêque Gareth Veal Alain Astier	2014	European Journal of Cancer2014，，：	2
	7	Usefulness of chemotherapy beyond the second line for metastatic breast cancer: a therapeutic challenge显示文摘	Elodie Vauléon Habiba Mesbah Brigitte Laguerre Daniel Gédouin Claudia Lefeuvre-Plesse Jean Levêque Odile Audrain Pierre Kerbrat	2010	Cancer Chemotherapy and Pharmacology2010，，1：	1

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