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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Fatigue behavior of high-entropy alloys: A review显示文摘Fatigue failures cost approximately 4% of the United States' gross domestic product(GDP). The design of highly fatigue-resistant materials is always in demand. Different from conventional strategies of alloy design, high-entropy alloys(HEAs) are defined as materials with five or more principal elements, which could be solid solutions. This locally-disordered structure is expected to lead to unique fatigue-resistant properties. In this review, the studies of the fatigue behavior of HEAs during the last five years are summarized. The four-point-bending high-cycle fatigue coupled with statistical modelling, and the fatigue-crack-growth behavior of HEAs, are reviewed. The effects of sample defects and nanotwins-deformation mechanisms on four-point-bending high-cycle fatigue of HEAs are discussed in detail. The influence of stress ratio and temperature on fatigue-crack-growth characteristics of HEAs is also discussed. HEAs could exhibit comparable or greater fatigue properties, relative to conventional materials. Finally,the possible future work regarding the fatigue behavior of HEAs is suggested. | CHEN PeiYong LEE Chanho WANG Shao-Yu SEIFI Mohsen LEWANDOWSKI John J DAHMEN Karin A JIA HaoLing XIE Xie CHEN BiLin YEH Jien-Wei TSAI Che-Wei YUAN Tao LIAW Peter K | 2018 | Science China(Technological Sciences)2018，61，2： | 3 |
| 4 | Microbial Biofilms显示文摘 | J W Costerton Z Lewandowski D E Caldwell D R Korber H M Lappin-Scott | 1995 | Annual Review of Microbiology1995，，： | 2 |
| 5 | Water use efficiency and biomass partitioning of three different miseanthus genotypes with limited and unlimited water supply 显示文摘 | Clifton-brown J C Lewandowski I | 2000 | Annals of Botany2000，86，1： | 1 |
| 6 | Miscanthus:european experience with a novel energy crop显示文摘 | LEWANDOWSKI I CLIFTON-BROWN J C SCURLOCK J M O | 2000 | Biomass &Biocnergy2000，19，4： | 1 |
| 7 | Mechanical properties of bulk metallic glasses显示文摘 | YAVARI A R LEWANDOWSKI J J ECKERT J | | 0，，8： | 1 |
| 8 | Fracture characteristics of an Al-Si-Mg model composite system显示文摘 | MANOHARAN M HUNT W H | 1993 | Materials Science & Engineering A: Structural Materials: Properties Microstructure and Processing1993，172，12： | 1 |
| 9 | Laminated Nanostrueture Composites with Improved Bend Ductility and Toughness显示文摘 | Hassan H A Lewandowski J J | 2009 | Scripta Materialia2009，61，： | 1 |
| 10 | The development and current status of perennial rhizomatous grasses as energy crops in the US and Europe显示文摘 | Lewandowski I Scurlock J M O Lindvall E | 2003 | Biomass and Bioenergy2003，25，4： | 1 |
| 11 | Microbial biofilm显示文摘 | COSTERTON J W LEWANDOWSKI Z CALDWE- LL D E | 1995 | Ann Rev Mierobiol1995，49，： | 1 |
| 12 | Increased circulating levels of matrix metalloproteinase - 2 and - 9 in women with the polycystic ovary syndrome 显示文摘 | Lewandowski KC Komorowski J O Callaghan CJ | 2006 | J Clin Endocrinol Metab2006，91，3： | 1 |
| 13 | Increased circulating levels of matrix metaUoproteinase-2 and -9 in women with the polycystic ovary syndrome显示文摘 | Lewandowski K C Komorowski J O'Callaghan C J | 2006 | J Clin Endocrinol Metab2006，91，3： | 1 |
| 14 | Microbial biofdm 显示文摘 | Costerton J W Lewandowski Z Caldwell DE | 1995 | Annu Rev Microbiol1995，49，： | 1 |
| 15 | Fracture toughness and notched toughness of bulk amorphous alloy: Zr-Ti-Ni-Cu-Be 显示文摘 | Lowhaphandu P Lewandowski J J | 1998 | Scripta Mater1998，38，12： | 1 |
| 16 | Miscanthus: European experience with a novel energy crop显示文摘 | Lewandowski I Clifton Brown J C Scurlock J M O | 2000 | Biomass and Bioenergy2000，19，4： | 1 |
| 17 | Strength and ductile-phase toughening in the two-phase Nb/Nb5Si3 alloys 显示文摘 | Mendiratta M G Lewandowski J J Dimiduk D M | 1991 | Metallurgical Transactions A1991，22，： | 1 |
| 18 | Simvastatln reduces sympathetic activity in patients with hypertension and hypercholesterolemia显示文摘 | Lewandowski J Siski M Bidiuk J et a1 | 2010 | Hypertens Res2010，33，11： | 1 |
| 19 | A tobacco mosaic virus-hybrid expresses and loses an added gene显示文摘 | LEWANDOWSKI D J HILF M E | 1989 | Virology1989，172，： | 1 |
| 20 | Biomass production potentials in Central and Eastern Europe under different scenarios显示文摘 | Van DAM J FAAIJ A P C LEWANDOWSKI L FISCHER G | 2007 | Biomass Bioenergy2007，31，6： | 1 |
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