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97篇 您的检索式:作者名="Lewis MC"
    题名 作者 年代 出处 被引量
1Pancreatic cancer: Are 'liquid biopsies' ready for prime-time?显示文摘Pancreatic cancer is a disease that carries a poor prognosis. Accurate tissue diagnosis is required. Tumours contain a high content of stromal tissue and therefore biopsies may be inconclusive. Circulating tumour cells(CTCs) have been investigated as a potential 'liquid biopsy' in several malignancies and have proven to be of prognostic value in breast, prostate and colorectal cancers. They have been detected in patients with localised and metastatic pancreatic cancer with sensitivities ranging from 38%-100% using a variety of platforms. Circulating tumour DNA(ct DNA) has also been detected in pancreas cancer with a sensitivity ranging from 26%-100% in studies across different platforms and using different genetic markers. However, there is no clear consensus on which platform is the most effective for detection, nor which genetic markers are the most useful to use. Potential roles of liquid biopsies include diagnosis, screening, guiding therapies and prognosis. The presence of CTCs or ct DNA has been shown to be of prognostic value both at diagnosis and after treatment in patients with pancreatic cancer. However, more prospective studies are required before this promising technology is ready for adoption into routine clinical practice.Alexandra R Lewis Juan W Valle Mairead G Mc Namara 2016World Journal of Gastroenterology2016,22,32:5
2In vitro fertilization and pregnancy rates; the influence of sperm motility and mor- phology on 1V foutcome显示文摘Donnelly ET Lewis SE Mc Nally JA 1998Fertil1998,70,2:1
3Uncomplicated general anesthesia in the elderly results in cognitive decline:does cognitive decline predict morbidity and mortality显示文摘Lewis MC Nevo I Paniagua MA 0,,03:1
4Mitochondrial toxicity of antiviral drugs显示文摘Lewis W Dalakis MC 1995Nat Med1995,1,:1
5Post-operative delirium: The tryptophan dyregulation model显示文摘Lewis MC Barnett SR 2004Med Hypotheses2004,63,3:1
6Mitochondrial toxicity of antiviral drugs显示文摘Lewis W Dalakas MC 1995Nat Med1995,1,5:1
7Rapid sevoflurane lnduction compared with thiopental显示文摘Lewis MC TerRiet M DelaCruz L 2004J Clin Anesth2004,16,4:1
8Surgical repair of aortic root aneurysms in 280 patients显示文摘Lewis CT Cooley DA Murphy MC 1992Ann Thorac Surg1992,53,:1
9Thin-Skin electromagnetic fields around surface-breaking cracks in metals显示文摘Lewis AM Michael DH Lugg MC 1998J Appl Phys1998,64,8:1
10Colostomy or ileostomy after colorectal anastomosis?:a randomised trial显示文摘Khoury GA Lewis MC Meleagros L 1987Ann R Coll Surg Engl1987,69,1:1
11Mitoehondrial toxicity of antiviral drugs 显示文摘Lewis W Dalakas MC 1995Nat Med1995,1,5:1
12In vitro fertilization and pregnancy rates;the influence of sperm motility and morphology on Ⅳ Foutcome显示文摘Donnelly ET Lewis SE Mc Nally JA 1998Fertil1998,70,2:1
13Neurofibrillary Tangles, Amyotrophy and Progrssive Motor Disturbance in Mice Expressing Mutant(P301L)Tau Protein显示文摘Lewis J Mc Gowan E Rockwood J 2000Nat Genet (S1061-4036)2000,25,:1
14Colostomy or ileostomy after colorectal anastomosis?:a randomised trial显示文摘Khoury GA Lewis MC Meleagros L 1987Ann R Coll Surg Engl1987,69,1:1
15The NINCDS-ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease : A clinic-pathologic study of 57 cases显示文摘Tierney MC Fisher RH Lewis AJ 1988Neurology1988,38,:1
16Mitochondrial toxicity of antiviral drugs 显示文摘Lewis W Dalakis Mc 1995Nat Med1995,1,:1
17Impact severity of local recurrence in giant cell tumor of bone显示文摘Mc Gough RL Rutledge J Lewis VO 2005Clin Orthop Relat Res2005,,438:1
18Selection of astaxanthin-overproducing mutants of Phaffia rhodozyma with β-ionone显示文摘Lewis MJ Ragot N Berlant MC 1990Applied and Environmental Microbiology1990,56,9:1
19Uncomplicated general anesthesia in the elderly results in cognitive decline: does cognitive decline predict morbidity and mortality 显示文摘Lewis MC Nero I Paniagua MA 2007Med Hypotheses2007,,68:1
20The concentration of vitamin A in the blood plasma during pregnacy显示文摘Bodansky O Lewis JM Lillienfeld MC 1943Clin Invest1943,22,5:1
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