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| 1 | Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms显示文摘协调的子宫胚胎的轴形成并且蜕膜的改变是哺乳动物的培植以后的胚胎开发的特点。胚胎子宫的取向在起始的培植被决定并且与蜕膜的开发同步。然而,控制这些事件的分子的机制留下尽管有它的发现逃犯很长时间以前。在现在的学习,我们发现了 Rbpj 的那子宫特定的删除,槽口发信号的原子变换器,在培植以后的阶段导致了反常胚胎子宫的取向和蜕膜的 patterning,导致实质的胚胎损失。我们进一步表明在胚胎附件以前, Rbpj 授与在时间上经由身体上与子宫的雌激素受体交往的子宫的腔形状转变(ERα) 以一种槽口小径无关的方式,它为在有子宫的轴的排列的胚胎取向的起始的建立是必要的。当时在培植以后的阶段, Rbpj 直接以一种槽口小径依赖者方式调整子宫的矩阵 metalloproteinase 的表示,它为正常被要求培植以后的蜕膜的改变。这些结果证明子宫的 Rbpj 为经由指示起始的胚胎子宫的取向并且以一种阶段特定的方式保证正常蜕膜的 patterning 的正常胚胎开发是必要的。我们的数据也证实正常哺乳动物的胚胎子宫的取向要求的概念合适的指导从发展地控制了子宫的发信号。 | Shuang Zhang Shuangbo Kong Bingyan Wang Xiaohong Cheng Yongjie Chen Weiwei Wu Qiang Wang Junchao Shi Ying Zhang Shumin Wang Jinhua Lu John P Lydon Francesco DeMayo Warren S Pear Hua Han Haiyan Lin Lei Li Hongmei Wang Yan-ling Wang Bing Li Qi Chen Enkui Duan Haibin Wang | 2014 | Cell Research2014，24，8： | 12 |
| 2 | Finite element analysis and design in stainless steel sheet forming and its experimental comparison显示文摘 | Lei L P Hwang S M Kang B S | 2001 | Journal of Materials Processing Technology2001，110，1： | 2 |
| 3 | High concentrations of sVCAM-1 and slCAM-1 in the cerebrospinal fluid of patients with intracerebral haemorrhage are associated with poor outcome显示文摘 | Kraus J Oschmann P Leis S | 2002 | J Neurol Neurosurg Psychiatry2002，73，3： | 1 |
| 4 | Analysis and Design of Hydroforming Process for Automobile Rear Axle Housing by FEM显示文摘 | LEI L P KIMJ KANG B S | 2000 | Machine Tools Manuf2000，40，12： | 1 |
| 5 | Municipal wastes and their solar transformities: An emergy synthesis for Macao显示文摘 | Lei K P Wang Z S | 2008 | Waste Management2008，28，12： | 1 |
| 6 | Deformation mechanisms and constitutive modeling for silicon nitride undergoing laser-assisted machining显示文摘 | LEI S SHIN Y C INCROPERA F P | | 0，，15： | 1 |
| 7 | The GCN2 eIF2a kinase is required for adaptation to amino acid deprivation in mice显示文摘 | Zhang P McGrath BC Reinert J Olaen DS Lei L Gill S | 2002 | Mol Cell Biol2002，22，19： | 1 |
| 8 | Filtration dynamics of the zebra mussel Dreissena polymorpha显示文摘 | Jin Lei Barry S P Shiao Y W | 1996 | Can J Fish Aquat Sci1996，53，： | 1 |
| 9 | Pulsatile flow in an end-to-side vascular graft model:comparison of computationas with experimental data显示文摘 | Lei M Giddens D P Jones S A | 2001 | J Biomechanical Engineering2001，123，： | 1 |
| 10 | Compositional and structural studies of DC magnetron sputtered SiC films on Si(111)显示文摘 | LEI Y M YU Y H REN C X ZOU S C CHEN D H WONG S P WILSON I H | 2000 | Thin Solid Films2000，365，： | 1 |
| 11 | Reversible watermarking scheme for medical image based on differential evolution显示文摘 | Lei B Y Tan E L Chen S P | 2014 | Expert Systems with Applications2014，41，7： | 1 |
| 12 | Effective Cell Capture with Tetrapeptide-Functionalized Carbon Nanotubes and Dual Signal Amplification for Cytosensing and Evaluation of Cell Surface Carbohydrate显示文摘 | Cheng W Ding L Lei J P Ding S J Ju H X | | 0，，10： | 1 |
| 13 | Laser direct marking ap- plied to rasterizing miniature data matrix code on alumi- num alloy显示文摘 | LI X S HE W P LEI L | 2016 | Opt Laser Technol2016，77，： | 1 |
| 14 | Molecular mechanisms of biocatalytic desulfurization of fossil fuels显示文摘 | Kevin A G Olga S P Gregry T M Lei X Daniel J M Charles H S | 1996 | Nature Biotechnology1996，14，12： | 1 |
| 15 | Dedifferentiation derived ceils exhibit pheno typic and functional characteristics of epidermal stem eells显示文摘 | Zhang C Fu X Chen P Bao X Li F Sun X Lei Y Cai S Sun T Sheng Z | 2009 | J Cell Mol Med2009，14，5： | 1 |
| 16 | Arsenic, cadmium, and lead pollution and uptake by rice (Oryza sativa L) grown in greenhouse显示文摘 | LEI MING TIE BALQING WILLIAMS S P N | 2011 | Journal of Soils and Sediments2011，11，1： | 1 |
| 17 | Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease显示文摘 | Ayton S Lei P Duce JA | 2013 | Ann Neu- rol2013，73，4： | 1 |
| 18 | The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy 显示文摘 | Zhang S Lei P Liu X | 2009 | Endocr Relat Cancer2009，16，： | 1 |
| 19 | Influence of microstructure on the hy- drogen permeation of alumina coatings 显示文摘 | He D Li S Liu X P Zhang C Yu Q H Lei Y Wang S M Jiang L J | 2013 | International Journal of Hydrogen Energy2013，38，22： | 1 |
| 20 | Pyrene-inducedchanges of glutathione-S-transferase activities in diferent microalgal species 显示文摘 | LEI A P WONG Y S TAM N F | 2003 | Chemosphere2003，50，3： | 1 |
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