|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A 5.7–6.4GHz GaAs HBT Power Amplifier with a Gain Enhanced Bias Circuit显示文摘This paper describes the design of a 5.7–6.4GHz Ga As Heterojunction bipolar transistor(HBT)power amplifier for broadband wireless application such as wireless metropolitan area networks.A bias circuit is proposed which enhances the power gain and provides a good linearity.Using the wideband matching network techniques with trap circuits embedded to filter the harmonics and the diode-based linearizing techniques,a broadband power amplifier module was obtained which exhibited a gain above 28d B.This is about 1d B improvement compared with those normal bias circuits at a supply voltage of 5V in the frequency range of 5.7–6.4GHz,measured with Continuous wave(CW)signals.The saturated output power was greater than 33d Bm in 5.7–6.4GHz and the output 1d B compression point was greater than 31d Bm.The phase deviation was less than 5 degrees when the output power below 33d Bm.The second and third order harmonic components were also less than-45d Bc and-50d Bc. | ZHENG Ruiqing ZHANG Guohao YU Kai LI Sizhen ZHENG Yaohua | 2017 | Chinese Journal of Electronics2017，26，3： | 7 |
| 2 | Analyses of factors forming offshore SST anomaly (O-SSTA) in China seas显示文摘Based on the observations, the location and the strength of warm(cold) anomaly of SST in surnmer are conrolled mainly by the subtropical highs of atmosphere (typhoon track) on the off shore of the China seas. It may be considered for the physical causes that the factors forming O-SSTA include the dynamic respome of upper layer ocean on tbe strong atmospheric forcing and the shallow sea effects. The former consists of the entrainment, the detrainment, the Ekman pumping and the convergence of surface warm watet; the later the tidal mixing and higher absorptivity. The parameterized expressions and the significance estimations of each factor are shown. The differences of both forming mechanisms and forming time-scales between the warm anomaly and the cold one are also indicated with different forcing systems. | Wang Sizhen, Li Xuhua, Qi Jianhua and Su Yusong (Ocean University of Qingdao, Qingdao 266003, China) | 1998 | Acta Oceanologica Sinica1998，17，4： | 4 |
| 3 | A numerical forecasting model of offshore-SST anomaly显示文摘An SST model which is good at predicting offshore-SST anomaly (O-SSTA) has been developed. It is composed of three parts: equations of dynamics, equations of model’s physics and equations of affecting factors of O-SSTA. Initial field of SST is prepared for a case of O-SSTA on last decade of July 1994, in which there are a center of warm anomaly in the Huanghai Sea and a center of cold anomaly in the East China Sea to be developing simultaneously. Using the Observed atmospheric forcing, the (decade) experiment forecast is made. Forecasting accuracy of warm (cold) anomaly is 32/44 (29/33 )’ the ensemble accuracy reaches R = 91% and AMD = 0. 67 t. The chief affecting factors of O-SSTA for this case are shown, for warm anomaly: (1 ) afar radiation (weight is 64 % ), (2) the convergence of warm water (9% ), (3 ) shallow-water effects; and for cold anomaly: (l) pumping of typhoon (44 % ), (2) entrainment of storm (24 % ), (3) latent heat (19 % ), respectively. It is identified that the formation of warm (cold) anomaly is a slower (faster) process. | Wang Sizhen Li Xuhua Qi Jianhua and Su Yusong (1. Ocean University of Qingdao, Qingdao 266003, China.) | 2000 | Acta Oceanologica Sinica2000，19，1： | 1 |
| 4 | Characteristics of optic disc parameters and its association in normal Chinese population: the Handan Eye Study显示文摘 | Zhang Qing Li Sizhen Liang Yuanbo Wang Fenghua Chen Weiwei Wang Ningli | 2014 | Chinese Medical Journal2014，，9： | 1 |
| 5 | Designing acom-pact soft-start scheme for voltage-mode DC-DCswitchingconverters显示文摘 | Li Sizhen Zou Xuecheng Chen Xiaofei | 2010 | Microelectronics Journal2010，，2： | 1 |
| 6 | Designing a compact soft-start scheme for voltage-mode DC-DC switching converters显示文摘 | Li Sizhen Zou Xuecheng Chen Xiaofei | 2010 | Microelectronics Journal2010，41，： | 1 |
| 7 | Characteristics of TP53 germline variants and their correlations with Li-Fraumeni syndrome or Li-Fraumeni-like syndrome in Chinese tumor patients显示文摘Li-Fraumeni syndrome(LFS),a rare autosomal-dominant inheritance condition,is associated with a family cancer history as well as pathogenic/likely-pathogenic TP53 germline variants(P/LP TP53 GV).The current clinical methods for detecting LFS are limited.Here,we retrospectively investigate P/LP TP53 GV among Chinese cancer patients by next-generation sequencing and evaluate its relationship with a family cancer history.A total of 270 out of 19,226 cancer patients have TP53 GV,including 53 patients with P/LP TP53 GV.Patients with P/LP TP53 GV are mainly found in male with glioma,lung cancer or sarcoma.The median age of diagnosis for P/LP TP53 GV patients is significantly lower than that of non-P/LP TP53 GV patients(31-years vs.53-years;P<0.01).One LFS patient and 3 Li-Fraumeni-like syndrome(LFL)patients are among the 26 followed-up P/LP TP53 GV patients.Among 25 types of P/LP TP53 GV,the highest variant frequencies occurred at codon 175 and 248.p.M237 I,p.R158 H,p.C238 Y and p.C275 R,are firstly identified among the Chinese LFS/LFL patients.This study reports the(P/LP)TP53 GV characteristics of Chinese pan-cancer patients.These findings suggest analyzing the P/LP TP53 GV in cancer patients is an effective strategy for identifying cancer predisposition syndrome. | Panwen Tian Xiaoyan Zhang Sheng Yang Yu Fang Hongling Yuan Wei Li Honglin Zhu Fangping Zhao Jinlei Ding Yunshu Zhu Sizhen Wang Guochen Sun Hongbin Ni Tonghui Ma Ting Lei | 2022 | Journal of Genetics and Genomics2022，49，7： | 0 |
| 8 | PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism显示文摘Metabolic reprogramming is a hallmark of cancer,including lung cancer.However,the exact underlying mechanism and therapeutic potential are largely unknown.Here we report that protein arginine methyltransferase 6(PRMT6)is highly expressed in lung cancer and is required for cell metabolism,tumorigenicity,and cisplatin response of lung cancer.PRMT6 regulated the oxidative pentose phosphate pathway(PPP)flux and glycolysis pathway in human lung cancer by increasing the activity of 6-phosphogluconate dehydrogenase(6PGD)and a-enolase(ENO1).Furthermore,PRMT6 methylated R324 of 6PGD to enhancing its activity;while methylation at R9 and R372 of ENO1 promotes formation of active ENO1 dimers and 2-phosphoglycerate(2-PG)binding to ENO1,respectively.Lastly,targeting PRMT6 blocked the oxidative PPP flux,glycolysis pathway,and tumor growth,as well as enhanced the antitumor effects of cisplatin in lung cancer.Together,this study demonstrates that PRMT6 acts as a posttranslational modification(PTM)regulator of glucose metabolism,which leads to the pathogenesis of lung cancer.It was proven that the PRMT6-6PGD/ENO1 regulatory axis is an important determinant of carcinogenesis and may become a promising cancer therapeutic strategy. | Mingming Sun Leilei Li Yujia Niu Yingzhi Wang Qi Yan Fei Xie Yaya Qiao Jiaqi Song Huanran Sun Zhen Li Sizhen Lai Hongkai Chang Han Zhang Jiyan Wang Chenxin Yang Huifang Zhao Junzhen Tan Yanping Li Shuangping Liu Bin Lu Min Liu Guangyao Kong Yujun Zhao Chunze Zhang Shu-Hai Lin Cheng Luo Shuai Zhang Changliang Shan | 2023 | Acta Pharmaceutica Sinica B2023，13，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员