| 1 | Rational design of a bifunctional fluorescent probe for distinguishing Hcy/Cys from GSH with ideal properties显示文摘By pairing two fluoropho res according to their optical prope rties such as absorption spectral overlap and absorptivity,fluorescent quantum yield and emission spectral separation,a bifunctional fluorescent probe,TQBF-NBD,was rationally designed and synthesized to discriminatively sense Hcy/Cys and GSH with good selectivity and sensitivity.It is noted that this probe could work under a single-wave length excitation and displayed a mega-large Stokes shift.TQBF-NBD reacted with Hcy/Cys to give a mixed green-red fluorescence and displayed a red fluorescence upon the treatment with GSH.Distinguishable imaging of intracellular Hcy/Cys from GSH with the help of TQBF-NBD was realized in living cells and zebrafish. | Xiaojie Ren Lide Liao Zhaoguang Yang Haipu Li Xi Li Yangang Wang Yong Ye Xiangzhi Song | 2021 | Chinese Chemical Letters2021，32，3： | 0 |
| 2 | PRESSURE FORCE CONTROL FOR FABRICATION OF PLASTIC MICROFLUIDIC CHIPS WITH HOT EMBOSSING METHOD显示文摘A pressure force control system for hot embossing of microfluidic chips is designed with a moment motor and a ball bearing lead screw. Based on the numeric PID technique, the algorithm of pulsant integral accelerated PID control is presented and the negative effects of nonlinearity from friction, clearance and saturation are eliminated. In order to improve the quick-response characteristic, independent thread technique is adopted. The method of pressure force control based on pulsant integral accelerated PID control and independent thread technique is applied with satisfactory control performance. | LIU Chong LIAO Junfeng WANG Xiaodong WANG Liding | 2007 | Chinese Journal of Mechanical Engineering2007，20，1： | 0 |
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