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| 1 | The spatial distribution of major and trace elements of surface sediments in the northeastern Beibu Gulf of the South China Sea显示文摘A multi-index analysis including grain size, major and trace elements is performed on the surface sediments from the northeastern Beibu Gulf to trace the sources of the sediments and to understand the controlling factors for elements distribution. The mean grain size exhibits a wide variation ranging from 0.09Φ to 8.05Φ with an average value of 5.33Φ. The average contents of major elements descend in an order of c(SiO_2)>c(Al_2O_3)>c(Fe_2O_3)>c(CaO)>c(MgO)>c(K_2O)>c(Na_2O)>c(TiO_2)>c(P_2O_5)>c(MnO), while those of trace elements exhibit a descending order of c(Sr)>c(Rb)>c(V)>c(Zn)>c(Cr)>c(Pb)>c(Ni)>c(Cu)>c(As). On the basis of elementary distribution characteristics and statistical analyses, the study area is divided into the four zones: Zone I is located in the northeastern coastal area of the gulf, which receives large amount of fluvial materials from local rivers in Guangxi and Guangdong, China, and the Qiongzhou Strait; Zone Ⅱ is located in the center of the study area, where surface sediments exhibits a multiple source; Zone Ⅲ is located in the Qiongzhou Strait, where surface sediments are dominated by materials from the Zhujiang River and Hainan; Zone IV is located in the southwest of the study area, where surface sediments are mainly originated from the Red River and Hainan. The statistical analyses of sediment geochemical characteristics reveal that the grain size, which is mainly influenced by hydrodynamics and mineral composition of terrigenous materials, is the leading factor controlling the elementary distribution.Meanwhile, impacts from anthropogenic activities and marine biogenic process will also be taken into consideration. | Qian Ge George Z Xue Liming Ye Dong Xu Jianru Zhao Fengyou Chu | 2019 | Acta Oceanologica Sinica2019，38，3： | 5 |
| 2 | A New PCR/LDR-Based Multiplex Functional Molecular Marker for Marker-Assisted Breeding in Rice显示文摘Marker-assisted selection or marker-aided selection(MAS)provides an effective complementary approach for conventional rice breeding with precise and speedy mobilization of target genes into elite genetic backgrounds.The targeted genes,however,may not be selected in the course of MAS due to the occasional recombination between the marker and the target gene/QTL during the many cycles of meiosis involved in breeding programs.This leads to failure in the selection of target traits(Gopalakrishnan et al,2008). | Chu Huangwei Tu Rongjian Niu Fuan Zhou Jihua Sun Bin Luo Zhongyong Cheng Can Cao Liming | 2021 | Rice science2021，28，1： | 3 |
| 3 | Cardiac Na^(+)-Ca^(2+) exchanger 1(ncx1h)is critical for the ventricular cardiomyocyte formation via regulating the expression levels of gata4 and hand2 in zebrafish显示文摘Ca^(2+) signaling is critical for heart development;however,the precise roles and regulatory pathways of Ca^(2+) transport proteins in cardiogenesis remain largely unknown.Sodium-calcium exchanger 1(Ncx1)is responsible for Ca^(2+) efflux in cardiomyocytes.It is involved in cardiogenesis,while the mechanism is unclear.Here,using the forward genetic screening in zebrafish,we identified a novel mutation at a highly-conserved leucine residue in ncx1 gene(mutant^(LDD353)/ncx1h^(L154P))that led to smaller hearts with reduced heart rate and weak contraction.Mechanistically,the number of ventricular but not atrial cardiomyocytes was reduced in ncx1h^(L154P) zebrafish.These defects were mimicked by knockdown or knockout of ncx1h.Moreover,ncx1h^(L154P) had cytosolic and mitochondrial Ca^(2+) overloading and Ca^(2+) transient suppression in cardiomyocytes.Furthermore,ncx1h^(L154P) and ncx1h morphants downregulated cardiac transcription factors hand2 and gata4 in the cardiac regions,while overexpression of hand2 and gata4 partially rescued cardiac defects including the number of ventricular myocytes.These findings demonstrate an essential role of the novel 154th leucine residue in the maintenance of Ncx1 function in zebrafish,and reveal previous unrecognized critical roles of the 154th leucine residue and Ncx1 in the formation of ventricular cardiomyocytes by at least partially regulating the expression levels of gata4 and hand2. | Liming Chu Huimin Yin Lei Gao Li Gao Yu Xia Chiyuan Zhang Yi Chen Tingxi Liu Jijun Huang Kenneth R.Boheler Yong Zhou Huang-Tian Yang | 2021 | Science China(Life Sciences)2021，64，2： | 3 |
| 4 | A Microsatellite Genetic Linkage Map of Black Rockfish(Sebastes schlegeli)显示文摘Ovoviviparous black rockfish(Sebastes schlegeli) is an important marine fish species for aquaculture and fisheries in China. Genetic information of this species is scarce because of the lack of microsatellite markers. In this study, a large number of microsatellite markers of black rockfish were isolated by constructing microsatellite-enriched libraries. Female- and male-specific genetic linkage maps were constructed using 435 microsatellite markers genotyped in a full-sib family of the fish species. The female linkage map contained 140 microsatellite markers, in which 23 linkage groups had a total genetic length of 1334.1 c M and average inter-marker space of 13.3 c M. The male linkage map contained 156 microsatellite markers, in which 25 linkage groups had a total genetic length of 1359.6 c M and average inter-marker distance of 12.4 c M. The genome coverage of the female and male linkage maps was 68.6% and 69.3%, respectively. The female-to-male ratio of the recombination rate was approximately 1.07:1 in adjacent microsatellite markers. This paper presents the first genetic linkage map of microsatellites in black rockfish. The collection of polymorphic markers and sex-specific linkage maps of black rockfish could be useful for further investigations on parental assignment, population genetics, quantitative trait loci mapping, and marker-assisted selection in related breeding programs. | CHU Guannan JIANG Liming HE Yan YU Haiyang WANG Zhigang JIANG Haibin ZHANG Quanqi | 2014 | Journal of Ocean University of China2014，13，6： | 2 |
| 5 | Activation of IGF2R induces mitochondrial-dependent apoptosis through Gαq and downstream calcineurin signaling in myocardial cells 显示文摘 | Chu Chun-Hsien Tzang Bor-Show Chert Liming | 2009 | Endocrinology2009，150，6： | 1 |
| 6 | IGF-Ⅱ/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Gaq interaction and protein kinase C-a/CaMKⅡ activation in H9c2 cardiomyoblast cells 显示文摘 | Chu Chun-Hsien Tzang Bor-Show Chen Liming | 2008 | Endocrinology2008，197，2： | 1 |
| 7 | Green-emitting PPE-PPV hybrid polymers: Efficient energy transfer across the m-phenylene bridge 显示文摘 | Chu Qinghui Pang Yi Ding Liming | 2003 | Macromolecules2003，36，11： | 1 |
| 8 | Self-assembled monolayers in perovskite solar cells显示文摘Perovskite solar cells(PSCs)have attracted great attention due to excellent power conversion efficiency(PCE),low cost and simple solution processing.The certified PCE has reached 25.5% from the initial efficiency of 3.8%,being comparable to that of commercial crystalline silicon solar cells[1,2].The efficiency boosting is mainly ascribed to the excellent properties of halide perovskite materials,including suitable bandgaps,high absorption coefficient,long carrier diffusion length and high defect tolerance[3]. | Liang Chu Liming Ding | 2021 | Journal of Semiconductors2021，42，9： | 1 |
| 9 | Positive periodic solutions of Hill's equations with singular nonlinear perturbations 显示文摘 | CHU Jifeng LIMing | 2008 | Nonlinear Anal: Theor2008，69，1： | 1 |
| 10 | Distribution of Eight Blast-resistant Genes in Parents of Three-line Japonica Hybrid Rice显示文摘The distribution of rice blast-resistant genes Pi2, Pi5, Pi9, Pi54, Pia, Pib, Pit and Pita in 36 restoring lines and 42 sterile lines were detected using functional molecular markers. The results indicated that those eight blast-resistant genes distributed in the 78 tested lines at various frequencies. Six rice blast-resistant genes were detected in the sterile line Shen 11 A, containing the most rice blast-resistant genes among the 78 lines, whereas no rice blast-resistant gene was detected in the lines 8527 A, Xu1 A and 016 A. The genetic distance-based clustering analysis showed that those 78 lines could be divided into five groups. | Chu Huangwei Cheng Can Niu Fu’an Zhou Jihua Tu Rongjian Luo Zhongyong Wang Xinqi Cao Liming | 2018 | Plant Diseases and Pests2018，9，2： | 0 |
| 11 | Causative fault and seismogenic mechanism of the 2010 Suining M5.0 earthquake from joint modeling of seismic and InSAR data显示文摘Although the Sichuan basin is a stable block with low historical seismicity,the Suining M5.0 earthquake on January31,2010 occurred near the center of the basin,causing casualty and substantial damage.Previous studies have shown that the earthquake is very shallow and may occur in the sedimentary cover rocks,but its causative fault has not been identified.Based on local broadband seismic waveform data as well as a pair of ALOS PALSAR ascending orbit data,we explore the seismogenic mechanism via further constraining the source depth and the ruptured fault.The earthquake caused ground uplift in the southeast of the epicenter area,with a maximum line of sight displacement of about 13.6 cm,much larger than the displacement caused by a M5 earthquake at a typical depth of 10 km,which indicates that the earthquake is very shallow.Through joint inversion of seismic waveform and InSAR data,we obtain the moment magnitude of Suining earthquake as MW4.5,with the strike,dip,and rake of its fault plane as 17°,66° and 90°,respectively,and the centroid depth less than 1 km,supporting that the earthquake occurred at the shallow part of a high angle thrust fault dipping to the southeast.It is further confirmed that the earthquake may be triggered by the diffusion of high-pressure fluid migrating from the underside gas reservoir. | Wangwang GU Sidao NI Shuofan WANG Baolong ZHANG Xinglin LEI Risheng CHU Aizhi GUO Qiang SHEN Hansheng WANG Liming JIANG Minhan SHENG Jiajun CHONG | 2023 | Science China Earth Sciences2023，66，8： | 0 |
| 12 | Dimensionless Variation of Seepage in Porous Media with Cracks Stimulated by Low-Frequency Vibration显示文摘Pulse excitation or vibration stimulation was imposed on the low permeable formation with cracks to enhance the production or injection capacity.During that process,a coupling of wave-induced flow and initial flow in dual-porous media was involved.Researchers had done much work on the rule of wave propagation in fractured porous media,whereas attentions on the variation law of flow in developing low permeable formation with cracks under vibration stimulation were not paid.In this study,the effect of low-frequency vibration on the seepage in dual-porous media was examined for the application of wave stimulation technology in developing reservoirs with natural cracks.A model for seepage of single-phase liquid in porous media with cracks under low-frequency vibration excitation was built by combining wave propagating theory for porous media with cracks and dual-porous media seepage mechanics.A governing equation group for the model,which was expressed by dimensionless fluid and solid displacements,was derived and solved with a numerical method.Variable physical properties were simulated to check the applicability of external low-frequency vibration load on dual-porous media and a parametric study for various vibration parameters.Stimulation of low-frequency vibration affected flow velocities of crack and rock matrix fluids.Compared with that in single-porous media,the stimulation effect on the fluid inner matrix of dual-porous media was relatively weakened.Different optimal vibration parameters were needed to increase the channeling flow between the crack and rock matrix or to only promote the flow velocity in the rock matrix.The theoretical study examines wave-coupled seepage field in fractured porous media with results that are applicable for low-frequency stimulation technology. | Liming Zheng Xiaodong Han Xinjun Yang Qingzhong Chu Guanghui Li | 2020 | Computer Modeling in Engineering & Sciences2020，，3： | 0 |
| 13 | Advances in the Application of Perovskite Materials显示文摘Nowadays, the soar of photovoltaic performance of perovskite solar cells has set off a fever in the study of metal halide perovskite materials. The excellent optoelectronic properties and defect tolerance feature allow metal halide perovskite to be employed in a wide variety of applications. This article provides a holistic review over the current progress and future prospects of metal halide perovskite materials in representative promising applications, including traditional optoelectronic devices(solar cells, light-emitting diodes, photodetectors, lasers), and cutting-edge technologies in terms of neuromorphic devices(artificial synapses and memristors) and pressure-induced emission. This review highlights the fundamentals, the current progress and the remaining challenges for each application, aiming to provide a comprehensive overview of the development status and a navigation of future research for metal halide perovskite materials and devices. | Lixiu Zhang Luyao Mei Kaiyang Wang Yinhua Lv Shuai Zhang Yaxiao Lian Xiaoke Liu Zhiwei Ma Guanjun Xiao Qiang Liu Shuaibo Zhai Shengli Zhang Gengling Liu Ligang Yuan Bingbing Guo Ziming Chen Keyu Wei Aqiang Liu Shizhong Yue Guangda Niu Xiyan Pan Jie Sun Yong Hua Wu‑Qiang Wu Dawei Di Baodan Zhao Jianjun Tian Zhijie Wang Yang Yang Liang Chu Mingjian Yuan Haibo Zeng Hin‑Lap Yip Keyou Yan Wentao Xu Lu Zhu Wenhua Zhang Guichuan Xing Feng Gao Liming Ding | 2023 | Nano-Micro Letters2023，15，10： | 0 |
| 14 | Distribution Patterns of Major and Trace Elements and Provenance of Surface Sediments on the Continental Shelf off Western Guangdong Province and Northeastern Hainan Island显示文摘A coupled approach based on grain size and geochemical elements is used to trace the provenance of surface sediments and to confirm the distribution patterns of grain size and elements on the continental shelf off western Guangdong Province and northeastern Hainan Island. The mean grain size ranges from 0.05 φ to 7.28 φ with a mean value of 5.60 φ. The average concentra- tions of major elements descend in the order of SiO2 > Al2O3 > CaO > Fe2O3 > K2O > MgO > Na2O > TiO2 > P2O5 > MnO, while those of trace elements exhibit a descending order of Sr > Rb > Zn > V > Cr > Pb > Ni > Cu > As > Cd. On the basis of the distribution patterns of elements and results of statistical analysis, the study area is classified into three zones. Zone I locates on the continental shelf off western Guangdong Province, and the sediments are mainly from Pearl River, Taiwan Residents rivers, and small rivers nearby. Zone II locates in the eastern exit of Qiongzhou Strait and the coastal area off Leizhou Peninsula, and the sediments are mainly from the ero- sion products of Qiongzhou Strait and Hainan Island. Zone III locates off the eastern Hainan Island and the continental shelf deeper than 50 m isobaths, and the sediments are mainly from Hainan Island and coral reef. The influence from open water should also be considered. Results indicate that the grain size is the main controlling factor for major and trace element contents and that anthropo- genic impact and biological activity also play an important role in the distribution of these elements. | GE Qian XUE Z. George YE Liming XU Dong YAO Zhigang CHU Fengyou | 2019 | Journal of Ocean University of China2019，18，4： | 0 |
| 15 | Depletion of conventional mature B cells and compromised specific antibody response in bovine immunoglobulin μ heavy-chain transgenic mice显示文摘In this study,we introduced the bovine immunoglobulinμheavy-chain gene(the orphaned gene on BTA11)into mouse germline cells.Bovine IgM was highly expressed in selected transgenic lines,and it largely inhibited rearrangements of the endogenous immunoglobulin heavy chain(IgH)genes in these lines.The forced expression of bovine IgM resulted in reduced numbers of pro-and pre-B cells but increased the number of immature B cells in the transgenic mice.Bovine IgM-expressing B cells can migrate from the bone marrow to the spleen,but most of the cells are arrested at the T1 transitional B cell stage,leading to a significantly lower number of T2 transitional and mature B cells in the spleen.Although the serum concentrations of endogenous IgM and IgG in the transgenic mice were significantly decreased,the IgA levels were slightly increased compared to the WT mice.The bovine IgM level in the serum was only one-tenth to one-fifth of that of endogenous mouse IgM,suggesting that most of the serum immunoglobulin were contributed by endogenous IgH gene-expressing B cells.These transgenic mice also exhibited a lower frequency of unique complementarity determining region 3(CDR3)sequences in their VH repertoire and Vκrepertoire but exhibited an increased frequency of unique CDR3 in their Vλrepertoire.Compared to the WT mice,the transgenic mice had a significantly higher percentage of mouse IgMexpressing B cells that expressedλchains.Finally,we showed that the transgenic mice were deficient in a specific antibody response to antigen stimulation. | Min ZHANG Xueqian CHENG Dan CHU Jingwen LIANG Yi SUN Li MA Beilei XU Min ZHENG Meili WANG Liming REN Xiaoxiang HU Qingyong MENG Ran ZHANG Ying GUO Yunping DAI Robert AITKEN Ning LI Yaofeng ZHAO | 2014 | Frontiers of Agricultural Science and Engineering2014，1，2： | 0 |
| 16 | Development of Beam Diagnostic System and Its Software in Central Region of SSC显示文摘DevelopmentofBeamDiagnosticSystemandItsSoftwareinCentralRegionofSSC￥FangLiming;ZhangGuinuandChuZhenshengThebeamdiagnosticsyst... | Fang Liming Zhang Guinu and Chu Zhensheng | 1996 | IMP & HIRFL Annual Report1996，，1： | 0 |
| 17 | MECHANISMS UNDERLYING PRESSOR EFFECT OF ELECTROACUPUNCTURE:Ⅰ.ESSENTIAL NEURAL SUBSTRATES IN BRAIN显示文摘The electroacupuncture(EA)being delivered to“Zusanli-Sanyinjiao”acupomts reduced a pressor-tachycardia effect,this effect still remained(nearly unchanged)after decerebration between superior and inferior colliculus,indicating that the essential cen-tets of EA-pressor effect(EA-PE)are located in lower brain stem.The EA-PE could be at-tenuated by preinjection of atropine or phentolamine bilaterally into rostral ventrolateralmedulla(RVL)(but was not significantly influenced by propranolol or haloperidol).Elec-trolytic lesions of bilateral nucleus parabrachialis(NPB),reduced the EA-PE,while lesionof the area postrema did not.Taken together with our previous results that lesions of bilateral locus coeruleus(LC)also remarkably decreased the EA-PE,α-adrenoceptors in RVL mediated NPB-pressor re-sponse,and both α-adrenoceptors,M-cholinoceptors are involved in LC-pressor response:the present results indicate that activation of NPB-RVL(α-receplor)and LC-RVL(α-and Mreceptor)pressor system by EA is the essential central mechanism underlying EA-PE. | Ku Yunhui Huang Yuqiong Chu Zhiguo Zhang Liming Department of Physiology.Beijing Medical University,Beijing 100083.China | 1992 | World Journal of Acupuncture-Moxibustion1992，2，3： | 0 |
| 18 | Superfluorescence from halide perovskite nanocrystal superlattices显示文摘Progress has been made in accurately manipulating the size and shape of monodisperse nanocrystals over past 30 years.In 1993,Bawendi et al.synthesized monodisperse CdS,CdSe and CdTe nanocrystals with similar size by a hot-injec-tion method[1].After two years,they prepared CdSe nanocrys-tal superlattices by self-assembling method with two distinct morphologies:faceted colloidal crystals and ordered thin films.The size and spacing of nanocrystals were controlled with a nearly atomic precision[2].Then,engineering morpho-logy,interaction and surrounding environment are encour-aged to construct superlattices at atomic scale.Meanwhile,the advanced technologies like electron microscopy and X-ray related tools help scientists to deeply understand the struc-tures and properties of nanocrystal superlattices[3].Com-pared to individual nanocrystal,their superlattices indicate col-lective properties due to coupling between nanocrystals[4].For instance,their original properties are enhanced because the ordered nanocrystals interact with each other under the light,electric or magnetic field;new properties can be gener-ated by the periodically ordered structures of the assembly;and comprehensive properties can be obtained via assem-bling nanocrystals with different functions. | Liang Chu Lixiu Zhang Liming Ding | 2022 | Journal of Semiconductors2022，43，10： | 0 |
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