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| 1 | A Novel Photothermal Nanocrystals of Cu_7S_4 Hollow Structure for Efficient Ablation of Cancer Cells显示文摘Cu2-x S nanocrystals(NCs), characterized by low cost, low toxicity, high stability and high photothermal conversion efficiency, provide promising platforms as photothermal agents. Herein, a novel twostep synthesis has been developed for Cu7S4 nanocrystals with hollow structure using the as-prepared copper nanoparticles as starting a solid precursor followed by hot-injection of sulfide source.The Cu7S4 NCs exhibit intense absorption band at Near-infrared(NIR) wavelengths due to localized surface plasmon resonance(LSPR)mode, which can effectively convert 980 nm-laser energy into heat.Moreover, the localized high temperature created by Cu7S4 NCs under NIR irradiation could result in efficient photothermal ablation(PTA) of cancer cells in vivo, demonstrating a novel and promising photothermal nanomaterials. | Guosheng Song Linbo Han Weiwei Zou Zhiyin Xiao Xiao Juan Huang Zongyi Qin Rujia Zou Junqing Hu | 2014 | Nano-Micro Letters2014,6,2: | 2 |
| 2 | Degradation of benzene derivatives in the CuMgFe-LDO/persulfate system:The role of the interaction between the catalyst and target pollutants显示文摘A novel insight on the role of interactions between target pollutants and the catalyst in the copper-containing layered double oxide(LDO)-catalyzed persulfate(PS)system was elucidated in the present study.4-Chlorophenol(4-CP),as a representative benzene derivative with a hydroxyl group,was completely removed within 5 min,which was much faster than the reaction of monochlorobenzene(MCB)without a hydroxyl group,with the degradation efficiency of 31.7%in 240 min.Through the use of radical quenching and surface inhibition experiments,it could be concluded that the interaction between 4-CP and CuMgFe-LDO,rather than free radicals,played a key role in the decomposition of 4-CP,while only the free radicals participated in the MCB degradation process.According to electron paramagnetic resonance and Xray photoelectron spectroscopy data,the formation of a Cu(II)-complex between phenolic hydroxyl groups and surface Cu(II)was primarily responsible for the degradation of phenolic compounds,in which PS accepted one electron from the complex and generated sulfate radicals and chelated radical cations.The chelated radical cations transferred one electron to Cu(Ⅱ)followed by Cu(I)generation and pollutant degradation successively. | Yun Chen Da Ouyang Wenying Zhang Jingchun Yan Linbo Qian Lu Han Mengfang Chen | 2020 | Journal of Environmental Sciences2020,32,4: | 2 |
| 3 | Aquaporin 4 expression and ultrastructure of the blood-brain barrier following cerebral contusion injury显示文摘This study aimed to investigate aquaporin 4 expression and the ultrastructure of the blood-brain barrier at 2-72 hours following cerebral contusion injury,and correlate these changes to the formation of brain edema.Results revealed that at 2 hours after cerebral contusion and laceration injury,aquaporin 4 expression significantly increased,brain water content and blood-brain barrier permeability increased,and the number of pinocytotic vesicles in cerebral microvascular endothelial cells increased.In addition,the mitochondrial accumulation was observed.As contusion and laceration injury became aggravated,aquaporin 4 expression continued to increase,brain water content and blood-brain barrier permeability gradually increased,brain capillary endothelial cells and astrocytes swelled,and capillary basement membrane injury gradually increased.The above changes were most apparent at 12 hours after injury,after which they gradually attenuated.Aquaporin 4 expression positively correlated with brain water content and the blood-brain barrier index.Our experimental findings indicate that increasing aquaporin 4 expression and blood-brain barrier permeability after cerebral contusion and laceration injury in humans is involved in the formation of brain edema. | Xinjun Li Yangyun Han Hong Xu Zhongshu Sun Zengjun Zhou Xiaodong Long Yumin Yang Linbo Zou | 2013 | Neural Regeneration Research2013,8,4: | 2 |
| 4 | Toxic effects ofcitrinin on the male reproductive system in mice显示文摘 | HAN Qingqing YU Linbo GUO Yunqian | 2012 | Experimental andToxicologic Pathology2012,64,: | 1 |
| 5 | Toxic effects of citrinin on the male reproductive system in mice显示文摘 | Han Qingqing Yu Linbo Guo Yunqian Liu Shuqiang | 2010 | Experimental and Toxicologic Pathology2010,,: | 1 |
| 6 | A survey of script learning显示文摘Script is the structured knowledge representation of prototypical real-life event sequences.Learning the commonsense knowledge inside the script can be helpful for machines in understanding natural language and drawing commonsensible inferences.Script learning is an interesting and promising research direction,in which a trained script learning system can process narrative texts to capture script knowledge and draw inferences.However,there are currently no survey articles on script learning,so we are providing this comprehensive survey to deeply investigate the standard framework and the major research topics on script learning.This research field contains three main topics:event representations,script learning models,and evaluation approaches.For each topic,we systematically summarize and categorize the existing script learning systems,and carefully analyze and compare the advantages and disadvantages of the representative systems.We also discuss the current state of the research and possible future directions. | Yi HAN Linbo QIAO Jianming ZHENG Hefeng WU Dongsheng LI Xiangke LIAO | 2021 | Frontiers of Information Technology & Electronic Engineering2021,22,3: | 0 |
| 7 | Mussel-Inspired Adhesive Hydrogels: Chemistry and Biomedical Applications显示文摘Adhesive hydrogels are an emerging class of hydrogels that combine three-dimensional hydrated networks with adhesive properties.These properties facilitate intimate tissue-material contact in diverse biomedical applications,enhancing tissue joining,drug transport,and signal transmission.Inspired by the universal adhesiveness of mussel foot proteins,3,4-dihydroxyphenyl-L-alanine (DOPA) and its analogs have been extensively exploited for the fabrication of adhesive hydrogels,within which the DOPA moieties can not only serve as cross-linking mediators but also participate in various intermolecular and surface interactions to mediate wet adhesion.This mini-review highlights recent achievements in the development of mussel-inspired adhesive hydrogels,focusing on: (1) elucidating DOPA-mediated adhesion mechanisms through nanomechanical characterizations,(2) designing injectable adhesive hydrogels toward applications in drug delivery,hemostasis,and wound closure,which includes in situ gelling liquids and shear-thinning preformed hydrogels,and (3) fabricating tough adhesive hydrogels with enhanced mechanical properties for use in tissue regeneration,biosensing,and bioimaging,with typical examples of nanocomposite and double-network hydrogels.The challenges and prospects in this rapidly developing field are also discussed. | Jingsi Chen Linbo Han Jifang Liu Hongbo Zeng | 2023 | Chinese Journal of Chemistry2023,41,24: | 0 |