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您的检索式：作者名="Linpei Guo"
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| 1 | Amoeba-inspired magnetic microgel assembly assisted by engineered dextran-binding protein for vaccination against lifethreatening systemic infection显示文摘Vaccination is critical for population protection from pathogenic infections.However,its efficiency is frequently compromised by a failure of antigen retention and presentation.Herein,we designed a dextran-binding protein DexBP,which is composed of the carbohydrate-binding domains of Trichoderma reesei cellobiohydrolases Cel6A and Cel7A,together with the sequence of the fluorescent protein mCherry.DexBP was further prepared by engineered Escherichia coli cells and grafted to magnetic nanoparticles.The magnetic nanoparticles were integrated with a dextran/poly(vinyl alcohol)framework and a reactive oxygen species-responsive linker,obtaining magnetic polymeric microgels for carrying pathogen antigen.Similar to amoeba aggregation,the microgels self-assembled to form aggregates and further induced dendritic cell aggregation.This step-by-step assembly retained antigens at lymph nodes,promoted antigen presentation,stimulated humoral immunity,and protected the mice from lifethreatening systemic infections.This study developed a magnetic microgel-assembling platform for dynamically regulating immune response during protection of the body from dangerous infections. | Shuo Liu Yan Zhao Linpei Guo Qilin Yu | 2023 | Nano Research2023，16，1： | 0 |
| 2 | Synthesis and Crystal Structure of Europium Associate(C34H54N2O10)[Eu(NO3)5]显示文摘Lariatethersarerecognizedaspotentialcationbinders.Theyoferselectionandamodificationforthecationbindingabilityoftheparentcr... | Chen, Zhaohui Li, Fuyou Jin, Linpei Guo, Jianquan | 1999 | Journal of Rare Earths1999，17，1： | 0 |
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