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1篇 您的检索式：作者名="Lisa T.Jansen"

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		题名	作者	年代	出处	被引量
	1	Neither autophagy nor exercise training mode affect exercise-induced beneficial adaptations in high fat-fed mice显示文摘Exercise mitigates obesity-associated pathologies;however,there is controversy regarding optimal exercise interventions.Autophagy,is known to decrease during obesity and is an important moderator for exercise adaptations.Purpose:To investigate individual and combined effects of different exercise interventions and autophagy inhibition on exercise adaptations during obesity.Methods:C57BL/6J mice initiated 45%high fat diet at 8 weeks of age.After 6 weeks of diet,animals were divided into moderate(MOD)or high intensity interval training interventions(HIIT),animals were further divided into autophagy inhibition or vehicle conditions(n=10/group).Animals exercised and autophagy was inhibited 3X/week by NSC185058 injections,thereby blocking autophagosome formation.Interventions continued for 4 weeks.Results:High fat diet impaired glucose handling~17%;exercise interventions normalized glucoregulation to prehigh fat diet levels,without differences between any interventions.High fat diet induced~25%decrease in aerobic capacity,which returned to baseline after exercise interventions,with no differences between any interventions.No effects of autophagy inhibition were noted.Conclusions:HIIT and MOD training confer similar health-related adaptations.	Megan E.Rosa-Caldwell Lisa T.Jansen Seongkyun Lim Kirsten R.Dunlap Wesley S.Haynie Tyrone A.Washington Nicholas P.Greene	2020	Sports Medicine and Health Science2020，2，1：	0

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