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| 1 | Progress in Numerical Simulation of Solidification Process of Shaped Casting显示文摘Solidification simulation of manufacturing shaped casting which plays an important role in asSuring the soundness and quality of castings, in minimizing the trial production time and in reducing the manufacturing cost becomes one of the hottest topics of the new research frontiers of foundry technology at home and abroad. Practical three dimensional computer numerical simulation system for temperature distribution during solidification as well as shrinkage cavity and porosity prediction has already been put into application all over the world. Further fundamental researche5 on fluid flow, thermal stress and micro-modeling as well as practical approaches of numerical simulation of solidification process of shaped castings for routine analysis of foundry industry are still underway. | LIU, BC SHEN, HF LI, WZ | 1995 | Journal of Materials Science & Technology1995，11，5： | 18 |
| 2 | Mitochondrial neuronal uncoupling proteins:a target for potential disease-modification in Parkinson’s disease Philip显示文摘This review gives a brief insight into the role of mitochondrial dysfunction and oxidative stress in the converging pathogenic processes involved in Parkinson’s disease(PD).Mitochondria provide cellular energy in the form of ATP via oxidative phosphorylation,but as an integral part of this process,superoxides and other reactive oxygen species are also produced.Excessive free radical production contributes to oxidative stress.Cells have evolved to handle such stress via various endogenous anti-oxidant proteins.One such family of proteins is the mitochondrial uncoupling proteins(UCPs),which are anion carriers located in the mitochondrial inner membrane.There are five known homologues(UCP1 to 5),of which UCP4 and 5 are predominantly expressed in neural cells.In a series of previous publications,we have shown how these neuronal UCPs respond to 1-methyl-4-phenylpyridinium(MPP+;toxic metabolite of MPTP)and dopamine-induced toxicity to alleviate neuronal cell death by preserving ATP levels and mitochondrial membrane potential,and reducing oxidative stress.We also showed how their expression can be influenced by nuclear factor kappa-B(NF-B)signaling pathway specifically in UCP4.Furthermore,we previously reported an interesting link between PD and metabolic processes through the protective effects of leptin(hormone produced by adipocytes)acting via UCP2 against MPP+-induced toxicity.There is increasing evidence that these endogenous neuronal UCPs can play a vital role to protect neurons against various pathogenic stresses including those associated with PD.Their expression,which can be induced,may well be a potential therapeutic target for various drugs to alleviate the harmful effects of pathogenic processes in PD and hence modify the progression of this disease. | WL Ho Jessica WM Ho Hui-Fang Liu Danny HF So Zero HM Tse Koon-Ho Chan David B Ramsden Shu-Leong Ho | 2012 | Translational Neurodegeneration2012，1，1： | 3 |
| 3 | Connexin37 gene polymorphism and coronary artery disease in Taiwan 显示文摘 | Yeh HI Chou Y Liu HF | 2001 | Int J Cardio12001，81，2： | 1 |
| 4 | A gold nanorod based colorimetric probe for the rapid and selective detection of Cu~ ions 显示文摘 | Liu JM Wang HF Yan XP | 2011 | Analyst2011，136，19： | 1 |
| 5 | HSP90 inhibitor 17- AAG selectively eradicates lymphoma stem cells 显示文摘 | Newman B Liu Y Lee HF | 2012 | Cancer Res2012，72，： | 1 |
| 6 | Decreased eonnexin 43 and increased fibrosis in atrial regions susceptible to complex fractionated atrial electrograms 显示文摘 | Liu X Shi HF Tan HW | 2009 | Cardiology2009，114，1： | 1 |
| 7 | The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells显示文摘 | Chao JI Liu HF | | 0，，： | 1 |
| 8 | Pulsed electromagnetic fields on postmenopausal osteoporosis in southwest China:a randomized,active-controlled clinical trial显示文摘 | Liu HF Yang L He HC | 2013 | Bioelectromagnetics2013，34，4： | 1 |
| 9 | Prognostic factors of intraperitoneal chemotherapy for peritoneal carcinomatosis of gastric cancer:A retrospective study from a single center显示文摘 | Men HT Gou HF Liu JY | 2016 | Oncol Lett2016，11，5： | 1 |
| 10 | Analysis of trinucleotide repeats in different SCA loci in spinocerebellar ataxia patients and in normal population of Taiwan显示文摘 | Tsai HF Liu CS Leu TM | 2004 | Acta Neurol Scand2004，109，5： | 1 |
| 11 | Analysis of trinucleotide repeats in different SCA loci in spinocerebellar ataxia patients and in normal population of Taiwan显示文摘 | Tsai HF Liu CS Leu TM | 2004 | Acta Neurol Scand2004，109，： | 1 |
| 12 | Colloidal gold-based immunochromatographic assay for detection of ricin显示文摘 | Shyu RH Shyu HF Liu FW | 2002 | Toxicon2002，40，3： | 1 |
| 13 | Emodin potentiates the antitumor effects of gemcitabine in pancreatic cancer cells via inhibition of nuclear factor- kappa B显示文摘 | Liu A Chen H Tong HF | 2011 | Mol Med Rep2011，4，2： | 1 |
| 14 | Taiwan aneurysm registry: multivari- ate analysis of two-month, one-year, and two-year outcomes after endovas- cular and microsurgieal treatment of ruptured aneurysms 显示文摘 | Liu HM Wong HF Lee KW | 2013 | Interv Neuroradiol2013，19，： | 1 |
| 15 | Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysis 显示文摘 | Liu R Dong HF Guo Y | 2011 | Parasit Vectors2011，4，： | 1 |
| 16 | Survivin and p53 modulate quer- cetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells显示文摘 | Kuo PC Liu HF Chao JI | 2004 | J Biol Chem2004，279，55： | 1 |
| 17 | MiR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf显示文摘 | Xia HF He TZ Liu CM | 2009 | Cell Physiol Biochem2009，23，46： | 1 |
| 18 | Adenoviral-mcdiatcd gcnc expression of hepatocyte growth factor prcvcnts postoperativc peritoneal adhesion in a rat model 显示文摘 | LIU HJ WU CT DUAN HF | 2006 | Surgery2006，110，3： | 1 |
| 19 | APOE genotype and neuroimag- ing markers of Alzheimer's disease: systematic review and meta- analysis显示文摘 | Liu Y Yu JT Wang HF | 2015 | J Neurol Neurosurg Psychiatry2015，86，2： | 1 |
| 20 | Pulsed electromagnetlc fields on post- menopausal osteoporosis in southwest China: a randomized, active- controlled clinical trial 显示文摘 | Liu HF Yang L He HC | 2013 | Bioelectromagnetics2013，34，4： | 1 |
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