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2篇 您的检索式:作者名="Liu Pinyue"
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1The M476W/Q482H mutation of procaspase-8 rest ored caspase-8-mediated apoptosis显示文摘Caspase-8 is an initiator of apoptotic signalling,and aberrations in procaspase-8 have been verified to be associated with malignant tumours.However,it remains to be confirmed whether chemotherapy resistance is related to procaspase-8 aberrations in acute myeloid leukaemia(AML)patients.Procaspase-8 WT or mutant plasmids were constructed with molecular techniques and were transfected into HeLa cells with Lipofectamine.Apoptosis analysis was performed with annexin V-FITC in the cells overexpressing the WT or mutant procaspase-8 with or without TRAIL treatment.The cleavage of procaspase-8 or the expression of proteins downstream in the apoptotic cascade was detected by Western blotting.The dimerization of WT and mutant procaspase-8 proteins w as demonstrated with Co-IP.Li Ming Wei Le Zhang Xuemei Zhang Yinjun Jiang Jie Liu Pinyue 2021解剖学杂志2021,44,S01:0
2Highly Anisotropic Magnetism and Nearly Isotropic Magnetocaloric Effect in Mn_(3)Sn_(2)Single Crystals显示文摘Mn_(3)Sn_(2)has been proposed as an ideal material for magnetic refrigeration.It undergoes two successive ferromagnetic transitions(T_(C1)=262 K and T_(C2)=227 K)and one antiferromagnetic transition(TN=192 K).Herein we report,for the first time,the preparation of single crystals of Mn_(3)Sn_(2)from Bi flux.The resultant anisotropic magnetic properties and magnetocaloric effect are investigated along the three principal crystallographic directions of the crystal.Significant anisotropy of magnetic susceptibility and multiple field-induced metamagnetic transitions were found at low fields,whereas the magnetocaloric effect was found to be almost isotropic and larger than that of the polycrystalline one.The maximum magnetic entropy change amounts to-ΔSM=4.01 J·kg^(-1)·K^(-1)near T_(C1)under a magnetic field change of μ_(0)ΔH=5 T along the c-axis,with the corresponding refrigerant capacity of 1750 mJ·cm^(-3).Combined with a much wider cooling temperature span(~80 K),our results demonstrate Mn_(3)Sn_(2)single crystal to be an attractive candidate working material for active magnetic refrigeration at low temperatures.Jianli Bai Qingxin Dong Libo Zhang Qiaoyu Liu Jingwen Cheng Pinyu Liu Cundong Li Yingrui Sun Yu Huang Zhian Ren Genfu Chen 2023Chinese Physics Letters2023,40,12:0
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