|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Developing the Science Product Algorithm Testbed for Chinese Next-Generation Geostationary Meteorological Satellites:Fengyun-4 Series显示文摘Fengyun-4A(FY-4A), the first of the Chinese next-generation geostationary meteorological satellites, launched in2016, offers several advances over the FY-2: more spectral bands, faster imaging, and infrared hyperspectral measurements. To support the major objective of developing the prototypes of FY-4 science algorithms, two science product algorithm testbeds for imagers and sounders have been developed by the scientists in the FY-4 Algorithm Working Group(AWG). Both testbeds, written in FORTRAN and C programming languages for Linux or UNIX systems, have been tested successfully by using Intel/g compilers. Some important FY-4 science products, including cloud mask, cloud properties, and temperature profiles, have been retrieved successfully through using a proxy imager, Himawari-8/Advanced Himawari Imager(AHI), and sounder data, obtained from the Atmospheric Infra Red Sounder, thus demonstrating their robustness. In addition, in early 2016, the FY-4 AWG was developed based on the imager testbed—a near real-time processing system for Himawari-8/AHI data for use by Chinese weather forecasters.Consequently, robust and flexible science product algorithm testbeds have provided essential and productive tools for popularizing FY-4 data and developing substantial improvements in FY-4 products. | Min MIN Chunqiang WU Chuan LI Hui LIU Na XU Xiao WU Lin CHEN Fu WANG Fenglin SUN Danyu QIN Xi WANG Bo LI Zhaojun ZHENG Guangzhen CAO Lixin DONG | 2017 | Journal of Meteorological Research2017，31，4： | 35 |
| 2 | The characteristics of atmospheric CO_2 concentration variation of four national background stations in China显示文摘Atmospheric carbon dioxide is an important kind of greenhouse gas which influences global temperature. Its concentration variation could indicate the distribution of human and natural activities in various regions. Through the non-dispersive infrared method, flask sampling of atmospheric CO2 concen- tration was measured weekly at four national background stations including Waliguan, Shangdianzi, Lin’an, and Longfengshan. Based on the data collected from September 2006 to August 2007, along with the Waliguan station’s experience on in situ observational data processing, the selection methods for sampling data through the atmospheric background CO2 concentration analysis were preliminarily discussed. On the basis of this result, the variation features of the four typical regions’ atmospheric background CO2 concentration was analyzed for the first time. The results show that the atmospheric CO2 concentration at Waliguan, Shangdianzi, Lin’an, and Longfengshan is 383.5, 385.9, 387.8, and 384.3 ppm, respectively. During the research period, CO2 concentration at the Waliguan station changed slightly. However, the CO2 concentration changed sharply at the Shangdianzi and the Lin’an stations due to the great influence of human activities in the Jingjinji and the Changjiang Delta economic zones, and changed regularly with seasons at Longfengshan station under dual influences of human activities and plant photosynthesis. The results from this study can lay the foundation for more profound studies on atmospheric CO2 concentration level of different areas in China, and could be used to improve the understanding of carbon source and sink distribution. | LIU LiXin, ZHOU LingXi, ZHANG XiaoChun, WEN Min, ZHANG Fang, YAO Bo & FANG ShuangXi Key Laboratory for Atmospheric Chemistry, Centre for Atmosphere Watch and Services (CAWAS), Chinese Academy of Meteoro- logical Sciences (CAMS), China Meteorological Administration (CMA), Beijing 100081, China | 2009 | Science China Earth Sciences2009，52，11： | 26 |
| 3 | Measure theory of statistical convergence显示文摘The question of establishing measure theory for statistical convergence has been moving closer to center stage, since a kind of reasonable theory is not only fundamental for unifying various kinds of statistical convergence, but also a bridge linking the studies of statistical convergence across measure theory, integration theory, probability and statistics. For this reason, this paper, in terms of subdifferential, first shows a representation theorem for all finitely additive probability measures defined on the σ-algebra A of all subsets of N, and proves that every such measure can be uniquely decomposed into a convex combination of a countably additive probability measure and a statistical measure (i.e. a finitely additive probability measure μ with μ(k) = 0 for all singletons {k}). This paper also shows that classical statistical measures have many nice properties, such as: The set S of all such measures endowed with the topology of point-wise convergence on A forms a compact convex Hausdorff space; every classical statistical measure is of continuity type (hence, atomless), and every specific class of statistical measures fits a complementation minimax rule for every subset in N. Finally, this paper shows that every kind of statistical convergence can be unified in convergence of statistical measures. | CHENG LiXin LIN GuoChen LAN YongYi LIU Hui | 2008 | Science China Mathematics2008，51，12： | 26 |
| 4 | Clinical efficacy of 0.1% pranoprofen in treatment of dry eye patients:a multicenter, randomized, controlled clinical trial显示文摘 | Chen Jingyao Dong Fei Chen Wei Sun Xuguang Deng Yingping Hong Jing Zhang Mingchang Yang Wenzhao Liu Zuguo Xie Lixin | 2014 | Chinese Medical Journal2014，，13： | 18 |
| 5 | High-resolution remote sensing image-based extensive deformation-induced landslide displacement field monitoring method显示文摘 | Shanjun Liu Han Wang Jianwei Huang Lixin Wu | 2015 | International Journal of Coal Science & Technology2015，2，3： | 16 |
| 6 | Response-surface-based structural reliability analysis with random and interval mixed uncertainties显示文摘Traditional reliability analysis requires probability distributions of all the uncertain parameters.However,in many practical applications,the variation bounds can be only determined for the parameters with limited information.A complex hybrid reliability problem then will be caused when the random and interval variables coexist in a same structure.In this paper,by introducing the response surface technique,we develop a new hybrid reliability method to efficiently compute the interval of the failure probability of the structure due to the probability-interval hybrid uncertainty.The present method consists of a sequence of iterations.At each step,a response surface model is constructed for the limit-state function by using a quadratic polynomial and a modified axial experimental design method.An approximate hybrid reliability problem is created based on the response surface model,which is subsequently solved by an efficient decoupling approach.An updating strategy is suggested to improve the quality of the response surface and whereby ensure the reliability analysis precision.A computational procedure is then summarized for the whole iterations.Four numerical examples and also a practical application are provided to demonstrate the effectiveness of the present method. | HAN Xu JIANG Chao LIU LiXin LIU Jie LONG XiangYun | 2014 | Science China(Technological Sciences)2014，57，7： | 14 |
| 7 | Indoor SVOC pollution in China:A review显示文摘Epidemiological and toxicological studies have proved that semi-volatile organic compounds (SVOCs) may have significant adverse effects on human health.For example,phthalic acid esters (PAEs),polybrominated diphenyl ethers (PBDEs) and polycyclic aromatic hydrocarbons (PAHs) may harm the endocrine,reproductive and respiratory systems of humans.Moreover,some SVOCs are carcinogenic.This paper summarizes the source emission characteristics for typical SVOCs observed indoors,evaluates the gas-phase and particle-phase concentrations of indoor di-2-ethylhexyl phthalate (DEHP) under the steady-state condition,estimates the exposure of PAEs and the health risk of PAHs,and then proposes some solutions to some urgent problems for indoor SVOC pollution.The results show that the production and consumption quantities of plasticizers,coal and cigarettes in China are the highest in the world,and that the consumption of flame retardants and pesticides are also very high.As estimated,indoor plasticizer and flame retardant concentrations are higher in China than that of the developed countries such as the USA,which implies that indoor SVOC pollution may be more serious in China.According to the model analysis,DEHP remains mainly in the particle-phase under the steady-state condition;the particle-phase concentration of DEHP increases with increasing particle concentration.The exposure of DEHP is higher for children than it is for adults.It is estimated that 260 thousand people are diagnosed with cancer resulting from exposure to PAHs every year.A multidisciplinary approach to the further study of indoor SVOC pollution is necessary. | WANG LiXin ZHAO Bin LIU Cong LIN Hui YANG Xu ZHANG YinPing | 2010 | Chinese Science Bulletin2010，55，15： | 13 |
| 8 | Identification and standardization of maneuvers based upon operational flight data显示文摘To find a way of loads analysis from operational flight data for advanced aircraft,maneuver identification and standardization jobs are conducted in this paper. For thousands of sorties from one aircraft, after studying the flight attitude when performing actions, the start and end time of the maneuvers can be determined. According to those time points, various types of maneuvers during the flight are extracted in the form of multi-parameters time histories. By analyzing the numerical range and curve shape of those parameters, a characteristic data library is established to model all types of maneuvers. Based on this library, a computer procedure using pattern-recognition theory is programmed to conduct automatic maneuver identification with high accuracy. In that way, operational loads are classified according to maneuver type. For a group of identified maneuvers of the same type, after the processes of time normalization, trace shifting, as well as averaging and smoothing, the idealization standard time history of each maneuver type is established.Finally, the typical load statuses are determined successfully based on standard maneuvers. The proposed method of maneuver identification and standardization is able to derive operational loads effectively, and might be applied to monitoring loads in Individual Aircraft Tracking Program(IATP). | Wang Yongjun Dong Jiang Liu Xiaodong Zhang Lixin | 2015 | Chinese Journal of Aeronautics2015，28，1： | 13 |
| 9 | Composition, origin and weathering process of surface sediment in Kumtagh Desert, Northwest China显示文摘Kumtagh 沙漠是在中国的八最大的沙漠之一,但是因为存取的困难,以前糟糕调查我们的学科交差的学习。在这份报纸, 33 件代表性的表面沉积样品从在实验室荒芜、分析的 Kumtagh 被收集获得重矿物质部件和 geochemical 元素内容。结果证明重矿物质的各种各样的类型在这些样品是在场的,与绿帘石和角闪石的高水平。Si 和艾尔收起化学作文的大部分。与上面的大陆人外壳(UCC ) 的 geochemical 元素的平均作文相比,除了 Si 和 Ca,所有元素被弄空到某个度;Fe, Mg, Ca, P, Ti 和 Mn 在他们的内容有高关联系数。矿物质和 Kumtagh 荒芜的沉积的 geochemical 作文在 Altyn Tagh 山脉和 Taklamakan 沙漠的附近与 Altyn Tagh 山脉,和冲积/洪水的扇子的表面沉积的岩石的有类似,显示 Kumtagh 荒芜的沉积的一主要来源位于 Altyn Tagh 山脉。在 Aqik 山谷和 Shule 河的更低的活动范围的冲积沉积物和湖沉积是容易的被侵蚀并且搬运由强壮在东北弯屈进 Kumtagh 沙漠,形成沙漠的另一来源扔。一张 A-CN-K 第三的图证明由 Na 和 K 的损失捱过的弱度化学药品发生在这些沉积,而 A-CNK-FM 第三的图建议 Fe 和 Mg 经历了重要化学区别。物理捱过过程为 mafic 矿物质在好粒子引起容易的侵蚀和丰富,这样粗糙的荒芜的沙粒子能相对在 Fe 和 Mg 被弄空。在经历不太化学的捱过的干旱区域的沉积的矿物质和 geochemical 作文被物理捱过主要影响。 | XU Zhiwei LU Huayu ZHAO Cunfa WANG Xianyan SU Zhizhu WANG Zhenting LIU Hongyi WANG Lixin LU Qi | 2011 | Journal of Geographical Sciences2011，21，6： | 13 |
| 10 | Digital virtual flight testing and evaluation method for flight characteristics airworthiness compliance of civil aircraft based on HQRM显示文摘In order to incorporate airworthiness requirements for flight characteristics into the entire development cycle of electronic flight control system(EFCS) equipped civil aircraft, digital virtual flight testing and evaluation method based on handling qualities rating method(HQRM)is proposed. First, according to HQRM, flight characteristics airworthiness requirements of civil aircraft in EFCS failure states are determined. On this basis, digital virtual flight testing model,comprising flight task digitized model, pilot controlling model, aircraft motion and atmospheric turbulence model, is used to simulate the realistic process of a pilot controlling an airplane to perform assigned flight tasks. According to the simulation results, flight characteristics airworthiness compliance of the airplane can be evaluated relying on the relevant regulations for handling qualities(HQ) rating. Finally, this method is applied to a type of passenger airplane in a typical EFCS failure state, and preliminary conclusions concerning airworthiness compliance are derived quickly. The research results of this manuscript can provide important theoretical reference for EFCS design and actual airworthiness compliance verification of civil aircraft. | Liu Fan Wang Lixin Tan Xiangsheng | 2015 | Chinese Journal of Aeronautics2015，28，1： | 13 |
| 11 | Land Surface Displacement Geohazards Monitoring Using Multi-temporal InSAR Techniques显示文摘China has been affected by some of the world’s most serious geological disasters and experiences high economic damage every year.Geohazards occur not only in remote areas but also in highly populated cities.In the framework of the Dragon-432365 Project,this paper presents the main results and the major conclusions derived from an extensive exploitation of Sentinel-1,ALOS-2(Advanced Land Observing Satellite 2),GF-3(Gao Fen Satellite 3),and latest launched SAR(Synthetic Aperture Radar),together with methods that allow the evaluation of their importance for various geohazards.Therefore,in the scope of this project,the great benefits of recent remote sensing data(wide spatial and temporal coverage)that allow a detailed reconstruction of past displacement events and to monitor currently occurring phenomena are exploited to study different areas and geohazards problems,including:surface deformation of mountain slopes;identification and monitoring of ground movements and subsidence;landslides;ground fissure;and building inclination studies.Suspicious movements detected in the different study areas were cross validated with different SAR sensors and truth data. | Guang LIU Perski ZBIGNIEW Salvi STEFANO Thiebes BENNI Lixin WU Jinghui FAN Shibiao BAI Lianhuan WEI Shiyong YAN Rui SONG Bignami CHRISTIAN Tolomei CRISTIANO Stefan SCHNEIDERBAUER Joao Sousa JOAQUIM 无 | 2021 | Journal of Geodesy and Geoinformation Science2021，4，1： | 13 |
| 12 | Spatial-temporal variation in soil respiration and its controlling factors in three steppes of Stipa L. in Inner Mongolia, China显示文摘Grassland is the largest terrestrial ecosystem in China. It is of great significance to measure accurately the soil respiration of different grassland types for the contribution evaluation of the Chinese terrestrial ecosystem’s carbon emission to the atmospheric CO2 concentration. A three-year (2005-2007) field experiment was carried out on three steppes of Stipa L. in the Xilin River Basin, Inner Mongolia, China, using a static opaque chamber technique. The seasonal and interannual variations of soil respiration rates were analyzed, and the annual total soil respiration of the three steppes was estimated. The numerical models between soil respiration and water-heat factors were established respectively. Similar seasonal dynamic and high annual and interannual variations of soil respiration were found in all of the three steppes. In the growing season, the fluctuation of soil respiration was particularly evident. The coefficients of variation (CVs) for soil respiration in different growing seasons ranged from 54% to 93%, and the annual CVs were all above 115%. The interannual CV of soil respiration progressively decreased in the order of Stipa grandis (S. grandis) steppe > Stipa baicalensis (S. baicalensis) steppe > Stipa krylovii (S. krylovii) steppe. The annual total soil respiration for the S. baicalensis steppe was 223.62?299.24 gC m-2 a-1, 150.62-226.99 gC m-2 a-1 for the S. grandis steppe, and 111.31–131.55 gC m-2 a-1 for the S. krylovii steppe, which were consistent with the precipitation gradient. The variation in the best fitting temperature factor explained the 63.5%, 73.0%, and 73.2% change in soil respiration in the three steppes at an annual time scale, and the corresponding Q10 values were 2.16, 2.98, and 2.40, respectively. Moreover, the Q10 values that were calculated by soil temperature at different depths all expressed a 10 cm > 5 cm > surface in the three sampling sites. In the growing season, the soil respiration rates were related mostly to the surface soil moisture, and the 95.2%, 97.4%, and 93.2% variations in soil respiration in the three steppes were explained by the change in soil moisture at a depth of 0-10 cm, respectively. | QI YuChun DONG YunShe LIU LiXin LIU XingRen PENG Qin XIAO ShengSheng HE YaTing | 2010 | Science China Earth Sciences2010，53，5： | 12 |
| 13 | Petroleum Migration Direction of the Silurian Paleo-pools in the Tarim Basin, Northwest China显示文摘摘要:在这份报纸获得的结果显示 carbazole 类型混合物有高热的稳定性并且也在氧化和简历降级显示出稳定性。这种混合物仍然在分析干燥沥青样品有高集中和完全的分发,证明他们在学习 paleo 水池的石油移植是特别地有用的。在期间盆在在 Tarim 盆的 Tazhong 和 Tabei 区域的志留纪的油气体水池形成是第一阶段的(在志留纪时期的结束) 并且在 Awati 区域的秒阶段(在里面二叠) ,石油经历了长途的迁居。在志留纪的结束在在 Tazhong 的志留纪 paleo 水池的形成期间高举,石油主要在 Manjiaer 来自更低、中间的寒武纪的来源岩石下垂。石油向首先在 Tazhong 进入志留纪水库床的西南南方移居了。然后,它进一步沿着结构的带的高度从西北在志留纪以内移居了到东南到在 Tazhong 的志留纪 pinchout 边界的区域。在 Tabei 高举,在期间水池形成第一阶段,石油也从在 Manjiaer 的更低、中间的寒武纪的来源岩石下垂。它移植了西北进入在 Tabei 的志留纪水库床第一高举,然后迁居在志留纪水库以内在一样的方向继续,最后,石油在更高的位置被套住。在在志留纪的秒阶段水池形成期间,在在 Awati 附近的区域的床下垂,石油主要在 Awati 来自降低中间的寒武纪的来源岩石下垂。石油通过主要路径在 sag 附近在所有方向从产生中心移居了到志留纪水库,并且石油最后在更高的地点被套住。 | LIU Luofu ZHAO Yande HUO Hong CHEN Lixin CHEN Yuanzhuang ZHAO Suping LI Chao LI Shuangwen GUO Yongqiang LI Yan Key Lab for Hydrocarbon Accumulation Mechanism in the China University of Petroleum,Ministry of Education Basin and Reservoir Research Center, China University of Petroleum,Beijing 102249, China | 2008 | Acta Geologica Sinica(English Edition)2008，82，1： | 12 |
| 14 | Investigation on transient electromagnetic scattering from a randomly rough surface and the perfect electric conductor target with an arbitrary cross section above it显示文摘The Time-Domain-Integral-Equation (TDIE) method is proposed to analyze transient scattering interaction between a two-dimensional infinitely long conducting target with an arbitrary cross section and a one-dimensional rough surface. Based on the electric-field-integral-equation in time domain, the explicit and implicit solutions of MOT (Marching-on-time) are derived and presented. The current response at the center of the rough surface and the far electric field response with time in the composite model are calculated and analyzed. The numerical results are compared and verified with those obtained by conventional MOM-IDFT (Method of Moment-inverse discrete Fourier transform). Finally, the influence of the size, the location of the target and the incident angle on the current response and the far electric fields response are discussed in detail. | WANG Rui GUO LiXin LI Juan LIU XiaoYong | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，5： | 11 |
| 15 | Ball-covering property of Banach spaces that is not preserved under linear isomorphisms显示文摘By a ball-covering B of a Banach space X, we mean that it is a collection of open balls off the origin whose union contains the sphere of the unit ball of X. The space X is said to have a ball-covering property, if it admits a ball-covering consisting of countably many balls. This paper, by constructing the equivalent norms on l~∞, shows that ball-covering property is not invariant under isomorphic mappings, though it is preserved under such mappings if X is a Gateaux differentiability space; presents that this property of X is not heritable by its closed subspaces; and the property is also not preserved under quotient mappings. | CHENG LiXin CHENG QingJin LIU XiaoYan | 2008 | Science China Mathematics2008，51，1： | 11 |
| 16 | Daily variation characteristics of CO2 emission fluxes and contributions of environmental factors in semiarid grassland of Inner Mongolia, China显示文摘Fixed field experimental studies are carried out on daily variations of the undis- turbed community and soil respiration fluxes in different phenological phases of 2001―2002 in semiarid Aneurolepidium chinense steppe of Inner Mongolia, China using static black chamber method. Corresponding statistical analysis of the contributions of the water-heat factors (air temperature, ground temperature, surface soil water content) and ecological factors (above- ground biomass, underground biomass, litter biomass) to daily variation law of the undisturbed community and soil respiration fluxes as well as differences in daily respiration are also con- ducted. The results indicate that undisturbed community and soil respiration have apparent daily variation laws, daily variation patterns of respiration fluxes during different phenological phases are basically the same, and the variations of environmental factors only exert effect on CO2 emission intensities, while the effect on daily variation pattern of grassland CO2 emission fluxes is relatively small. The daily total respiration of the undisturbed community in different phenological phases ranges from 1.34―10.13 g·m?2; soil daily total respiration ranges from 0.98―5.17 g·m?2; both daily variations of undisturbed community and soil respiration fluxes are significantly corre- lated (p < 0.05) or extremely significantly correlated (p < 0.01) with air temperatures and ground surface temperatures, but the correlativity with the soil temperature at 5 and 10 cm depths is relatively weak; multiple regression analysis indicates that about 80% of the difference in daily respiration of the undisturbed community among different phenological phases is induced by the variation of the aboveground biomass, while the variations of the remaining factors can jointly explain around 20% of the daily respiration variations of the whole grassland ecosystem; about 83% of the soil daily respiration variation of the different phenological phases is caused by 0―20 cm underground biomass. Besides, surface soil water content is also an important environmental factor affecting soil daily respiration variations of the Aneurolepidium chinense steppe, but its partial correlation coefficient with soil daily respiration amount does not reach the significance level of 0.05. | QI Yuchun DONG Yunshe LIU Jiyuan GENG Yuanbo LI Mingfeng YANG Xiaohong LIU Lixin | 2005 | Science China Earth Sciences2005，48，7： | 11 |
| 17 | Clearance Influence on Dynamic Response of Intermittent Roller Chain Drive显示文摘The clearances appear in chain link hinges induced by manufacturing tolerance or wear of components are the most important factor that influences the dynamic performance of the intermittent roller chain drives.Due to the existence of the clearances in chain link hinges,the serious impact vibration phenomenon which influences the stability and the position accuracy of the chain drive system would be caused in the intermittent motion.But,the problem may be that a reasonable modeling on the chain with clearances is difficult due to the large clearance's number in chain system and the fact that the clearance' size are different.Currently,the studies on the dynamics of the intermittent roller chain considering the multi-clearance' joints are rare.Most research works have only focused on the constant moving chains.Taking the intermittent roller chain system as an object,this paper designs and builds the experimental device of this kind of mechanical system.The Longitudinal vibration response of the intermittent chain under the different motion laws was tested.The experimental study shows that the clearances presented in chain link hinges can cause severe impact vibration in the intermittent motion of chain.In subsequent work,the dynamic model of the intermittent roller chain system with the multi-clearance' joints was established.By calculating the dynamic response of this kind of mechanical system under the different motion laws,the effect of the clearances on the dynamic response of the intermittent chain drive system was analyzed.The theoretical simulation shows that the serious impact vibration phenomenon of the chain system can be caused by the clearances at the start accelerating period,and the chain drive system is often accompanied by the severe shock and vibration at the moment that the chain moves from the acceleration period to deceleration period.The research conclusions made by the experimental and theoretical studies indicate that the use of motion laws with small and continuous jerk at conversion point can effectively suppress the impact vibration at this point caused by clearances' effect.Additionally,the use of nonsymmetrical motion laws with small jerk approaching the end of the indexing period can obtain a smaller residual vibration.The presented motion law can provide an important reference for the improvement of the dynamic performance of the intermittent chain drive systems. | XU Lixin YANG Yuhu CHANG Zongyu SHEN Zhaoguang LIU Jianping | 2010 | Chinese Journal of Mechanical Engineering2010，23，6： | 11 |
| 18 | The historical and current research progress on jujube–a superfruit for the future显示文摘Jujube(Ziziphus jujuba Mill.),or Chinese date,is the most important species of Rhamnaceae,a large cosmopolitan family,and is one of the oldest cultivated fruit trees in the world.It originates from the middle and lower reaches of the Yellow River,the‘mother river’of the Chinese people.It is distributed in at least 48 countries on all continents except Antarctica and is becoming increasingly important,especially in arid and semiarid marginal lands.Based on a systematic analysis of the unique characteristics of jujube,we suggest that it deserves to be recognized as a superfruit.We summarized historical research achievements from the past 3000 years and reviewed recent research advances since 1949 in seven fields,including genome sequencing and application,germplasm resources and systematic taxonomy,breeding and genetics,cultivation theory and techniques,pest control,postharvest physiology and techniques,and nutrition and processing.Based on the challenges facing the jujube industry,we discuss eight research aspects to be focused on in the future. | Mengjun Liu Jiurui Wang Lili Wang Ping Liu Jin Zhao Zhihui Zhao Shengrui Yao Florin Stănică Zhiguo Liu Lixin Wang Changwei Ao Li Dai Xiansong Li Xuan Zhao Chunxiang Jia | 2020 | Horticulture Research2020，7，1： | 10 |
| 19 | Interrogation of Streptomyces avermitilis for efficient production of avermectins显示文摘The 2015 Nobel Prize in Physiology or Medicine has been awarded to avermectins and artemisinin,respectively.Avermectins produced by Streptomyces avermitilis are excellent anthelmintic and potential antibiotic agents.Because wild-type strains only produce low levels of avermectins,much research effort has focused on improvements in avermectin production to meet the ever increasing demand for such compounds.This review describes the strategies that have been widely employed and the future prospects of synthetic biology applications in avermectin yield improvement.With the help of genome sequencing of S.avermitilis and an understanding of the avermectin biosynthetic/regulatory pathways,synthetic and systems biotechnology approaches have been applied for precision engineering.We focus on the design and synthesis of biological chassis,parts,devices,and modules from diverse microbes to reconstruct and optimize their dynamic processes,as well as predict favorable effective overproduction of avermectins by a 4Ms strategy(Mine,Model,Manipulation,and Measurement). | Jinsong Chen Mei Liu Xueting Liu Jin Miao Chengzhang Fu Heyong Gao Rolf Muller Qing Zhang Lixin Zhang | 2016 | Synthetic and Systems Biotechnology2016，1，1： | 10 |
| 20 | Remodeling of motor cortex function in acute cerebral infarction patients following human urinary kallidinogenase A functional magnetic resonance imaging evaluation after 6 months显示文摘A total of 29 patients were treated within 48 hours after acute subcortical cerebral infarction with Xuesaitong or Xuesaitong plus human urinary kallidinogenase for 14 days.Neurological deficits,activity of daily living,and evaluations of distal upper limb motor functions at the 6-month follow-up showed that patients treated with Xuesaitong plus human urinary kallidinogenase recovered better than with Xuesaitong alone.In addition,functional MRI revealed that activation sites were primarily at the ipsilesional side of injury in all patients.Human urinary kallidinogenase induced hyperactivation of the ipsilesional primary sensorimotor cortex,premotor cortex,supplementary motor area,and contralesional posterior parietal cortex.Results showed that human urinary kallidinogenase improved symptoms of neurological deficiency by enhancing remodeling of long-term cortical motor function in patients with acute cerebral infarction. | Xuezhu Song Lixin Han Yan Liu | 2012 | Neural Regeneration Research2012，7，11： | 10 |
您所在的机构暂未开通此部分的功能，请联系管理员