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	题名	作者	年代	出处	被引量
1	Value of a newly sequenced bacterial genome显示文摘Next-generation sequencing(NGS) technologies have made high-throughput sequencing available to medium- and small-size laboratories, culminating in a tidal wave of genomic information. The quantity of sequenced bacterial genomes has not only brought excitement to the field of genomics but also heightened expectations that NGS would boost antibacterial discovery and vaccine development. Although many possible drug and vaccine targets have been discovered, the success rate of genome-based analysis has remained below expectations. Furthermore, NGS has had consequences for genome quality, resulting in an exponential increase in draft(partial data) genome deposits in public databases. If no further interests are expressed for a particular bacterial genome, it is more likely that the sequencing of its genome will be limited to a draft stage, and the painstaking tasks of completing the sequencing of its genome and annotation will not be undertaken. It is important to know what is lost when we settle for a draft genome and to determine the 'scientific value' of a newly sequenced genome. This review addresses the expected impact of newly sequenced genomes on antibacterial discovery and vaccinology. Also, it discusses the factors that could be leading to the increase in the number of draft deposits and the consequent loss of relevant biological information.	Eudes GV Barbosa Flavia F Aburjaile Rommel TJ Ramos Adriana R Carneiro Yves Le Loir Jan Baumbach Anderson Miyoshi Artur Silva Vasco Azevedo	2014	World Journal of Biological Chemistry2014，5，2：	7
2	Femtosecond pulsed laser deposition of diamond-like carbon thin films for tribological applications 显示文摘	Garrelie F Loir A S Donnet C	2003	Surface and Coatings Technology2003，，：	1
3	Circumstances of death and microscopic observations in a series of 200 cases of sudden death arrhythmogenic right ventricular cardiomyopathy and/or dysplasia 显示文摘	Tabib A Loire R Chalabreysse L	2003	Circulation2003，108，24：	1
4	Clinical presentation of left at rialcardiac myxoma:a series of 112 consecutive cases显示文摘	Duhaut P Loire R	2001	Medicine2001，80，：	1
5	Deposition of tetrahedral diamond-like carbon thin films by femtosecond laser ablation for applications of hip joints 显示文摘	Loir A S Garr elie F Donnet C	2004	Thin Solid Films2004，，：	1
6	An in-ducible surface presentation system improves cellular immunity against human papiUomavirus type 16 E7 antigen inmice after nasal administration with recom-binant lactococci 显示文摘	Bermudez-Humaran L G Cortes-Perez N G Le Loir Y	2004	Joumal of Medical Microbiology2004，53，5：	1
7	Production and Target- ing of the BruceUa abortusAntigen L7/L12 in theLactococcus lactis:a First Step towards Food-Grade Live Vaccines against Brucellosis显示文摘	Ribeiro LA Azevedo V Le Loir Y	2002	Applied and Environmental Microbiology2002，68，2：	1
8	Contralateral haemorrhagic pulmonary metastases('choriocarcinoma syndrome') after pneumonectomy for primary pulmonary choriocarcinoma显示文摘	Berger N Loire R	1994	Thorax1994，49，：	1
9	Circumstances of death and gross and microscopic observations in a series of 200 cases of sudden death associated with arrhythmogenic right ventricular cardiomyopathy and/or dysplasia显示文摘	Tabib A Loire R Chalabreysse L	2003	Circulation2003，108，24：	1
10	Staphylococcus alxreu and food poisoning显示文摘	Le Loir Y Baron F Gautier M	2003	Genet Mol Res2003，2，1：	1
11	Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis:a first step towards food-grade live vaccines against brucellosis显示文摘	Ribeiro L A Azevedo V Le Loir Y	2002	Appl Environ Microbiol2002，68，：	1
12	Signal peptide and propeptide optimization for heterologous protein secretion in Lactococcus lactis显示文摘	Loir Y L Nouaille S Commissaire J	2001	Appl Environ Microbiol2001，67，9：	1
13	Protein secretion in Lactococcus lactis: An efficient way to increase the overall heterologous protein production显示文摘	Loir Y L Azevedo V Oliveira S	2005	Microbial Cell Fact2005，4，：	1
14	Staphylococcus aureus and food poisoning显示文摘	Le Loir Y Baron F Gautier M	2003	Genet Mol Res2003，2，1：	1
15	Small-vessel vasculifis surrounding an uninflamed temporal artery: a new diagnostic criterion for polymyalgia rheumatiea 显示文摘	Chatelain D Duhaut P Loire R	2008	Arthritis Rheum2008，58，8：	1
16	A nine-residue synthetic propeptide enhances secretion efficiency of heterologous proteins in Lactococcus lactis显示文摘	Gruss A Ehrlich SD	1998	J Bacteriol1998，180，：	1
17	Saphylococcus aureus and food poisoning显示文摘	Le Loir Y Baron F Gautier M	2003	GenetMol Res2003，2，1：	1
18	Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis:a first step towards food-grade live vaccines against Brucellosis显示文摘	Azevedo V Le Loir Y	2002	Appl Environ Microbiol2002，68，：	1
19	Staphylococcus aureus and food poisoning显示文摘	LE LOIR Y BARON F GAUTIER M	2003	Genet Mol Res2003，2，1：	1
20	Clinical presentation of left atrial cardiac myxoma显示文摘	Pinede L Duhaut P Loire R	2001	Medicine2001，80，3：	1

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