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| 1 | Biomarkers for Parkinson's Disease:Recent Advancement显示文摘As a multi-factorial degenerative disease,Parkinson's disease(PD) leads to tremor, gait rigidity,and hypokinesia, thus hampering normal living. As this disease is usually detected in the later stages when neurons have degenerated completely, cure is on hold, ultimately leading to death due to the lack of early diagnostic techniques. Thus, biomarkers are required to detect the disease in the early stages when prevention is possible.Various biomarkers providing early diagnosis of the disease include those of imaging, cerebrospinal fluid,oxidative stress, neuroprotection, and inflammation. Also,biomarkers, alone or in combination, are used in the diagnosis and evolution of PD. This review encompasses various biomarkers available for PD and discusses recent advances in their development. | Sharvari Lotankar Kedar S Prabhavalkar Lokesh K Bhatt | 2017 | Neuroscience Bulletin2017，33，5： | 41 |
| 2 | Colour and organic removal of biologically treated coffee curing wastewater by electrochemical oxidation method显示文摘The treatment of biologically treated wastewater of coffee-curing industry by the electrochemical oxidation using steel anode was investigated. Bench-scale experiments were conducted for activated sludge process on raw wastewater and the treated effluents were further treated by electrochemical oxidation method for its colour and organic content removal. The efficiency of the process was determined in terms of removal percentage of COD, BOD and colour during the course of reaction. Several operating parameters like time, pH and current density were examined to ascertain their effects on the treatment efficiency. Steel anode was found to be effective for the COD and colour removal with anode efficiency of 0.118 kgCOD\5h -1\5A -1\5m -2 and energy consumption 20.61 kWh\5kg -1 of COD at pH 9. The decrease in pH from 9 to 3 found to increase the anode efficiency from 0.118 kgCOD\5h -1\5A -1\5m -2 to 0.144 kWh\5kg -1 of COD while decrease the energy consumption from 20.61 kWh\5kg -1 of COD to 12.86 kWh\5kg -1 of COD. The pH of 5 was considered an ideal from the present treatment process as it avoids the addition of chemicals for neutralization of treated effluents and also economical with respect to energy consumption. An empirical relation developed for relationship between applied current density and COD removal efficiency showed strong predictive capability with coefficient of determination of 96.5%. | Rajesh S. Bejankiwar K.S. Lokesh T.P. Halappa Gowda | 2003 | Journal of Environmental Sciences2003，15，3： | 7 |
| 3 | Surgical management of gastric stump cancer:a report of 37 cases显示文摘Objective: To observe the clinicopathological characteristics of gastric stump cancer (GSC) and evaluate the benefits of radical surgery of GSC. Methods: The clinicopathological characteristics and postoperative survival time of 37 GSC patients who underwent surgery were investigated retrospectively. The survival time was compared according to the type of surgical pTMN stage. Survival curves were traced by using Kaplan-Meier methods. Results: Most GSC (32/37) was detected in patients who had received Billroth Ⅱ reconstruction after partial gastrectomy for benign gastric disease. The lesser curvature side and the suture line of anastomosis were the most frequent sites where GSC occurred (27/37). Differentiated adenocarcinoma was the dominant histopathological type (24/37). The postoperative 5-year survival rate of early stage GSC patients (n=9) was significantly higher than advanced stage GSC (n=12) (55.6% vs 16.5%, xL2=1 1.48, P<0.01). Five-year survival rate of 21 GSC patients with radical resection were 75% (3/4) for stage Ⅰ, 60% (3/5) for stage Ⅱ, 14.2% (1/7) for stage Ⅲ, and 0% (0/5) for stage Ⅳ respectively.The median survival time of 21 GSC patients who underwent radical resection was longer than those undergoing palliative operation (43.0m vs 13.0m, xL2=36.31, P<0.01), the median survival time of stage Ⅳ patients with radical resection was 23.8months. Conclusions: Without remote metastasis, radical resection for GSC is possible, and is an effective way to improve the prognosis of GSC. Even in stage Ⅳ GSC, radical resection can still prolong the survival time. It is necessary for the patients with benign gastric diseases who received partial gastrectomy to carry out the endoscopy follow-up, especially in patients with Billroth Ⅱ reconstruction procedure at 15-20 years. | 陈力 田华 陈健 何志刚 陶思丰 LOKESH Gurung 彭淑牖 | 2005 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2005，6，1： | 4 |
| 4 | Alterations in lipid peroxides in rat liver by dietary n-3 fatty acids:modulation of antioxidant enzymes by curcumin,eugenol,and vitamin E显示文摘 | Reddy A C P Lokesh B R | 1994 | Journal of Nutritional Biochemistry1994，5，： | 1 |
| 5 | Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease:possible mechanisms显示文摘 | Kinsella J E Lokesh B Stone R A | 1990 | The American journal of clinical nutrition1990，52，1： | 1 |
| 6 | Cytomegalovirus-Associated Hemophagocytic Syndrome in a Child With Crohn Disease Receiving Azathioprine显示文摘 | T. G. Lokesh Babu Dana Boctor Alyson Davey Mason C. Bond Kevan Jacobson | 2004 | Journal of Pediatric Gastroenterology and Nutrition2004，，4： | 1 |
| 7 | ^14C-lignin-lignocellulose biodegradation by bacteria isolation from polluted soil 显示文摘 | Lokesh K V | 2001 | Indian Journal of Experimental Biology2001，39，6： | 1 |
| 8 | Speech Enhancement Using Mel-LPC Gepstrum and Vector Quantization for ASR显示文摘 | LOKESH S BALAKRISHNAN G | 2012 | European Journal of Scientific Research2012，73，2： | 1 |
| 9 | Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer显示文摘 | Lokesh D N Rit V Jyotsana S | 2011 | Biochem Pharm2011，82，9： | 1 |
| 10 | Effect of mycoflora on the physico -chemical characteristics of oil obtained from the infected sunflower,toria and sesame seeds显示文摘 | BEGUM M RAVISHANKAR RAI V Lokesh S | 2003 | Journal of food science and technology2003，40，6： | 1 |
| 11 | Familial monomelic amyot rophy: a case report from India显示文摘 | Nalini A Lokesh L Ratnavalli E | 2004 | J Neurol Sei2004，220，12： | 1 |
| 12 | Nitric oxide counters ethylene effects on ripening fruits显示文摘 | MANJUNATHA G GUPTA KJ LOKESH V MUR L A NEEL-WARNE B | 2012 | Plant Signaling & Behavior2012，7，4： | 1 |
| 13 | Conjugated Linoleic Acid (CLA) Formation in Edible Oils by Photoisomerization: A Review显示文摘 | Rahul Reddy Gangidi Belur Ramaswamy Lokesh | 2014 | Journal of Food Science2014，，5： | 1 |
| 14 | Nitric oxide in fruit ripening : trends and opportunities 显示文摘 | Manjunatha G Lokesh V Neelwarne B | 2010 | Biotechnology Advances2010，28，4： | 1 |
| 15 | Familial monomelic amyotrophy:a case report from India 显示文摘 | Nalini A Lokesh L Ratnavalli E | 2004 | J Neurol Sci2004，，12： | 1 |
| 16 | Effect of mycoflora on the physico-ehemical characteristics of oil obtained from the infected sunflower, toria and sesame seeds 显示文摘 | BEGUM M RAI V R LOKESH S | 2003 | Food Sci Tech Mys2003，40，6： | 1 |
| 17 | Familial monomelic amyotrophy:a case report from India显示文摘 | Nalini A Lokesh L Ratnavalli E | 2004 | J Neurol Sci2004，220，12： | 1 |
| 18 | Role of capsaicin,curcumin and dietary n-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages显示文摘 | Joe B Lokesh BR | 1994 | Biochim Biophys Acta1994，1224，2： | 1 |
| 19 | MTTE and availability evaluation of a two unit two state, standby redundant complex system with constont human failure显示文摘 | Gupta P P Lokesh Tyagi | 1986 | Microelectron Reliab1986，26，4： | 1 |
| 20 | Nitric oxide counters ethylene effects on ripening fruits 显示文摘 | Manjunatha G Gupta K J Lokesh V | 2012 | Plant Signaling & Behavior2012，7，4： | 1 |
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