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463篇 您的检索式:作者名="Long A R"
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1Surgical treatment for liver cancer显示文摘Primary liver cancer is amongst the commonest tumors worldwide,particularly in parts of the developing world,and is increasing in incidence. Over the past three decades,surgical hepatic resection has evolved from a high risk,resource intensive procedure with limited application,to a safe and commonly performed operation with a range of indications. This article reviews the approach to surgical resection for malignancies such as hepatocellular cancer,metastatic liver de-posits and neuroendocrine tumors. Survival data after resection is also reviewed,as well as indications for curative resection.Nicole C Tsim Adam E Frampton Nagy A Habib Long R Jiao 2010World Journal of Gastroenterology2010,16,8:12
2Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS.Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight 2010Cellular & Molecular Immunology2010,7,3:3
3Optical properties of the metals Al, Co, Cu, Au, Fe, Pb, Ni, Pd, Pt, Ag, Ti, and W in the infrared and far infrared 显示文摘Ordal M A Long L L Bell R J 1983Applied Optics1983,22,7:2
4Trade,Wage Gapsand Specific Human Capital Accumulation显示文摘Long N V Riezman R Soubeyran A 2007Review ofInternational Economics2007,15,6:1
5Radiation characteristics of thin-wire ternary fractal trees 显示文摘Werner D H Rubio B A Long B R 1996Electronics Letters1996,35,8:1
6Monitoring electrical resistance of concretes containing alternative cementitious materials to assess their resistance to chloride penetration显示文摘Basheer P A M Gilleece P R V Long A E 2002Cement and Concrete Composites2002,24,5:1
7Why assess the properties of near-surface concrete?显示文摘Long L A G D Henderson F R Montgomery 2001Construction and Building Materials2001,15,:1
8Group 4 metal olefin polymerization catalysts stabilized by bidentate O,Pligands显示文摘Long R J Gibson V C White A J P 0,,:1
9显示文摘Ordal M A Long L L Bell R J 1983Appl Opt1983,22,7:1
10Optical properties of the metals Al,Co,Cu,Au,Fe,Pb,Ni,Pd,Pt,Ag,Ti and W in the infrared and far infrared显示文摘M A Ordal L L Long R J Bell 0,,:1
11Variation in availability of emergency contraception in pharmacies显示文摘SHACTER H E GEE R E LONG J A 2007Contraception2007,75,3:1
12Porous media equivalents for networks of discontinuous fractures显示文摘Long J C S Remer J S Wilson C R Witherspoon P A 1982Water Resources Research1982,18,3:1
13The cultural manage- ment of flu-cured tobacco quality 显示文摘WEYBREW J A WANISMAIL W A LONG R C 1983Tobacco International1983,185,10:1
14Age related susceptibility of newborn pigs to the cutaneous application of ehlorpyri- fos显示文摘LONG G G SCHEIDT A B EVERSON R J 1986Veterinary and Human Toxicology1986,28,4:1
15Optical properties of the metals AI,Co,Cu,Au,Fe,Pb,Ni,Pd,Pt,Ag,Ti,and W in the infrared and far infrared显示文摘ORDAL M A LONG L L BELL R J 1983App Opt1983,22,2:1
16In vivo photoinduction of metallothionein in human skin by ultraviolet irradiation显示文摘Anstey A Marks R Long C 1996J Pathol1996,178,1:1
17Analyzing the responses of photosynthetic CO2 assimilation to long-term elevation of atmospheric CO2 concentration显示文摘LONG S P BAKER N R RAINES C A 1993Vegetation1993,,:1
18Heat flux measurement techniques显示文摘Childs P R N Greenwood J R Long C A 1999Pro Instn Mech Engrs1999,213,:1
19Frequency-stabilized cavity ring-down spectroscopy 显示文摘Long D A Cygan A Van Zee R D Okumura M Miller C E Lisak D Hodges J T 2012Chemical Physics Letters2012,536,:1
20The culturalmanagement of flue-cured tobacco quality显示文摘Weybrew J A Wan Ismail W A Long R C 1983Tobaccointernational1983,185,10:1
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