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| 1 | The role of endoscopy in the management of hereditary diffuse gastric cancer syndrome显示文摘Hereditary diffuse gastric cancer(HDGC) syndrome is an inherited cancer risk syndrome associated with path-ogenic germline CDH1 variants. Given the high risk for developing diffuse gastric cancer, CDH1 carriers are recommended to undergo prophylactic total gastrectomy for cancer risk reduction. Current guidelines recommend upper endoscopy in CDH1 carriers prior to surgery and then annually for individuals deferring prophylactic total gastrectomy.Management of individuals from HDGC families without CDH1 pathogenic variants remains less clear, and management of families with CDH1 pathogenic variants in the absence of a family history of gastric cancer is particularly problematic at present. Despite adherence to surveillance protocols, endoscopic detection of cancer foci in HDGC is suboptimal and imperfect for facilitating decision-making. Alternative endoscopic modalities, such as chromoendoscopy,endoscopic ultrasound, and other non-white light methods have been utilized,but are of limited utility to further improve cancer detection and risk stratification in HDGC. Herein, we review what is known and what remains unclear about endoscopic surveillance for HDGC, among individuals with and without germline CDH1 pathogenic variants. Ultimately, the use of endoscopy in the management of HDGC remains a challenging arena, but one in which further research to improve surveillance is crucial. | Shria Kumar Jessica M Long Gregory G Ginsberg Bryson W Katona | 2019 | World Journal of Gastroenterology2019，25，23： | 2 |
| 2 | Genetic polymorphism of Malus sieversii populations in Xinjiang, China 显示文摘 | Yan G R Long H Song W Q | 2008 | Genet Resour Crop Evol2008，，55： | 1 |
| 3 | Isolation and characterization endophytic bacteria from Sedum alfredii Hance and their potential to promote phytoextraction of zinc polluted soil 显示文摘 | LONG X X CHEN X M CHEN Y G WONG J W WEI Z B WU Q T | 2010 | World Journal Microbiology Biotechnology2010，27，： | 1 |
| 4 | Limits to the velocity of solid armatures in railguns显示文摘 | Long G C Weldon W F | 1989 | IEEE Transactions on Magnetics1989，25，1： | 1 |
| 5 | The prevalence of schizophrenia in mainland China: evidenee from epidemiological surveys显示文摘 | LONG J HUANG G LIANG W | 2014 | AetaPsyehiatr Seand2014，130，4： | 1 |
| 6 | Catalytic amountsof Brnsted acidic ionic liquids promoted esterification:Study of acidity-activity relationship显示文摘 | Zhao Y W Long J X Deng F G | 2009 | Catal Comm2009，10，5： | 1 |
| 7 | Mapping and sequence of the gene for the pseudorabies virus glycoprotein which accumulates in the medium of infected eells显示文摘 | Rea T J Timmins J G Long G W | 1985 | J Virol1985，54，1： | 1 |
| 8 | Studies on comparison of esterase isozyme of different species of Trichogramma显示文摘 | CAO G L LU W Q LONG S | 1988 | Colloques de 1'' INRA1988，43，： | 1 |
| 9 | A stability algorithm for the general milling process显示文摘 | Sridhar R Hohn R E Long G W | 1968 | ASME Journal of Engineering for Industry1968，90，： | 1 |
| 10 | Integral Bifurcation Method and Its Application for Solving the Modified Equal Width Wave Equation and Its Variants显示文摘 | Rui W G Xie Sh L Long Y | 2007 | Rostock Math Kolloq2007，62，： | 1 |
| 11 | Structure of the New Nuclide ^259Db and Its α-decay Daughter Nuclei显示文摘 | Long W Meng J Zhou S G | 2002 | Phys Rev2002，65，04： | 1 |
| 12 | Penglai zircon megacrysts:a potential new working reference for microbeam Determination of Hf-O isotopes and U-Pb age显示文摘 | Li X H Long W G Li Q L | 2010 | Geostandards and Geoanalytical Research2010，34，2： | 1 |
| 13 | Multiobjective optimization for tapered circular tubes 显示文摘 | HOU S HAN X SUN G Y LONG S Y LI W YANG X J LI Q | 2011 | Thin- Walled Structures2011，49，7： | 1 |
| 14 | The ERBB4/HER4 intracellular domain 41CD is a BH3-only protein promoting apoptosis of breast cancer cells显示文摘 | NARESH A LONG W VIDAL G A | 2006 | Cancer Res2006，66，12： | 1 |
| 15 | Alkaline leaching Zn and its concomitant metals from refractory hemimorphite zinc oxide ore 显示文摘 | CHEN A L ZHAO Z W JIA X J LONG S HUO G S CHEN X Y | 2009 | Hydrometallurgy2009，97，： | 1 |
| 16 | Ultrasound of the plantar aponeurosis(fascia)显示文摘 | Gibbon W W Long G | 1999 | Skeletal Radiol1999，28，1： | 1 |
| 17 | Meehanoehemical leaching of refractory zinc silicate (hemimorphite) in alkaline solution 显示文摘 | ZHAO Z W LONG S CHEN A L HUO G S JIA X J CHEN X Y | 2009 | Hydrometallurgy2009，99，： | 1 |
| 18 | Sensitivity analysis of the scaled boundary finite element method for elastostatics显示文摘 | Long X Y Jiang C Han X Gao W Bi R G | 2014 | Computer Methods in AppliedMechanics and Engineering2014，276，： | 1 |
| 19 | Cyelooxygenase -2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carci- noma cell lines through a decrease in matrix metalloprotelnase - 2 and -9 activity显示文摘 | LI W W LONG G X LIU D B | 2014 | Pharmazie2014，69，2： | 1 |
| 20 | Catalytic amounts of Bronsted acidic ionic liquids promoted esterification: Study of acidity-activity relationship 显示文摘 | ZHAO Y W LONG J X DENG F G | 2009 | Catalysis Communications2009，10，5： | 1 |
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