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| 1 | Impact of formal training in endoscopic submucosal dissection for early gastrointestinal cancer: A systematic review and a meta-analysis显示文摘AIM: To summarize the clinical impact of a formal training for the effectiveness and safety of endoscopic submucosal dissection for gastrointestinal cancer.METHODS: We searched databases including PubM ed, EMBASE and the Cochrane Library and Science citation Index updated to August 2014 to include eligible articles. In the Meta-analysis, the main outcome measurements were en bloc resection rate, local recurrence rate(R0) and the incidence of procedure-related complications(perforation, bleeding). RESULTS: En bloc resection was high for both, dissecting stomach tumors with an overall percentage of 93.2%(95%CI: 90.5-95.8) and dissecting colorectal tumors with an overall percentage of 89.4%(95%CI: 85.1-93.7). Although the number of studies reporting R0 resection(the dissected specimen was revealed free of tumor in both vertical and lateral margins) was small, the overall estimates for R0 resection were 81.4%(95%CI: 72-90.8) for stomach and 85.9%(95%CI: 77.5-95.5) for colorectal tumors, respectively. The analysis showed that the percentage of immediate perforation and bleeding were very low; 4.96(95%CI: 3.6-6.3) and 1.4%(95%CI: 0.8-1.9) for colorectal tumors and 3.1%(95%CI: 2.0-4.1) and 4.8%(95%CI: 2.8-6.7) for stomach tumors, respectively. CONCLUSION: In order to obtain the same rate of success of the analyzed studies it is a necessity to create training centers in the western countries during the 'several years' of gastroenterology residence first only to teach EGC diagnose and second only to train endoscopic submucosal dissection. | Miguel A Tanimoto M Lourdes Guerrero Yoshinori Morita Jonathan Aguirre-Valadez Elisa Gomez Carlos Moctezuma-Velazquez Jose A Estradas-Trujillo Miguel A Valdovinos Luis F Uscanga Rikiya Fujita | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，4： | 2 |
| 2 | Preva lence of human T cell lymphotropic virus type 1 infection in hospi talized patients with tuberculosis显示文摘 | De Lourdes Bastos M Osterbauer B Mesquita DL | 2009 | Int J Tuberc Lung Dis2009，13，12： | 1 |
| 3 | p27kip1–838C>A Single Nucleotide Polymorphism Is Associated With Restenosis Risk After Coronary Stenting and Modulates p27kip1 Promoter Activity显示文摘 | Claudia M. van Tiel Peter I. Bonta Saskia Z.H. Rittersma Marcel A.M. Beijk Edward J. Bradley Anita M. Klous Karel T. Koch Frank Baas J Wouter Jukema Douwe Pons M Lourdes Sampietro Hans Pannekoek Robbert J. de Winter Carlie J.M. de Vries | 2009 | Circulation2009，，： | 1 |
| 4 | Nosocomial infec- tion in a community hospital in Mexico显示文摘 | de Lourdes Garcia2Garcia M Jimenez2Corona A 3imenez2orona ME | 2001 | In- fect Control Hosp Epidemol2001，22，6： | 1 |
| 5 | Ion-exclusion chromatographic determination of organic acids in vinegars显示文摘 | Lourdes Morales M Gustavo Gonzalez A Ana M Troncoso | 1998 | Journal of Chromatography A1998，822，： | 1 |
| 6 | Methodology for urinary 8-OHDG analysis by HPLC with electrochemical detection显示文摘 | De Martinis BS de Lourdes Pires Bianchi M | 2002 | Pharm Res2002，4，6： | 1 |
| 7 | Influence of methyl donor nutrients as epigenetic regulators in colorectal cancer:A systematic review of observational studies显示文摘BACKGROUND Dietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer(CRC).However,whether the influence of methyl donor intake is modified by polymorphisms in such epigenetic regulators is still unclear.AIM To improve the current understanding of the molecular basis of CRC.METHODS A literature search in the Medline database,Reference Citation Analysis(http://gffzzb1f9d057b5954674s6fw60k9fkf9x6q66.ffgz.tsg.suse.edu.cn/),and manual reference screening were performed to identify observational studies published from inception to May 2022.RESULTS A total of fourteen case-control studies and five cohort studies were identified.These studies included information on dietary methyl donors,dietary components that potentially modulate the bioavailability of methyl groups,genetic variants of methyl metabolizing enzymes,and/or markers of CpG island methylator phenotype and/or microsatellite instability,and their possible interactions on CRC risk.CONCLUSION Several studies have suggested interactions between methylenetetrahydrofolate reductase polymorphisms,methyl donor nutrients(such as folate)and alcohol on CRC risk.Moreover,vitamin B6,niacin,and alcohol may affect CRC risk through not only genetic but also epigenetic regulation.Identification of specific mechanisms in these interactions associated with CRC may assist in developing targeted prevention strategies for individuals at the highest risk of developing CRC. | Lourdes Pilar Chávez-Hidalgo Silvia Martín-Fernández-de-Labastida Marian M de Pancorbo Marta Arroyo-Izaga | 2023 | World Journal of Gastroenterology2023，29，7： | 1 |
| 8 | Nosocomial infection in a community hospital in Mexico 显示文摘 | De Lourdes Garcia-Garcia M Jimenez-Corona A Jimenez- Corona ME | 2001 | Infect Control Hosp EpidemoI2001，22，6： | 1 |
| 9 | Nosocomial infections in a community hospital in Mexico显示文摘 | de Lourdes Garcia-Garcia M Jimenez-Corona A Jimenez-Corona ME | 2001 | Infect Control Hosp Epidemiol2001，22，6： | 1 |
| 10 | Matrix metalloproteinases 2, 9, and 13, and tissue inhibitors of metalloproteinases 1 and2 in experimental lung silicosis显示文摘 | Perez-Ramas J de Lourdes Segura-Valdez M Vanda B | 1999 | Am J Respir Crit Care Med1999，160，4： | 1 |
| 11 | Non-targeted and targeted analysis of wild toxic and edible mushrooms using gas chromatography-ion trap mass spectrometry显示文摘 | CARVALHO L M CARVALHO F DE LOURDES BASTOS M | 2014 | Talanta2014，118，： | 1 |
| 12 | Streptokinase and Heparin versus Heparin Alone in Massive Pulmonary Embolism: A Randomized Controlled Trial 显示文摘 | Ramirez-Rivera A de Lourdes Garcia M | 1995 | J Thromb Thrombolysis1995，2，3： | 1 |
| 13 | INDITEP: the first pre - commercial DSG solar power plant 显示文摘 | EDUARDO ZARZA M ESTHER ROJAS LOURDES GONZALEZ | 2006 | Solar Energy2006，80，10： | 1 |
| 14 | Antioxidant Acton of Bixin Against CisplatinInduced Chromosome Aberrations and Lipid Peroxidation in Rats显示文摘 | Cec(I)lia Rodrigues Siva Lus(a)nua M Greggu Abtyes abd Maria De Lourdes P | 2001 | Pharmacological Research2001，43，6： | 1 |
| 15 | Synthesis of novel highly reactive silicone-epoxy mono- mers for cationic photopolymerizations 显示文摘 | ORTIZ R A de LOURDES GUILLIN CISNEROS M GARCIA G A | 2005 | Polymer2005，46，10： | 1 |
| 16 | The determinants of Spanish industrial exports to the European Union显示文摘 | Lourdes M | 1997 | Applied Economics1997，，30： | 1 |
| 17 | Muhiple mononeuritis and eosinophilic fasciitis in a patient with idiopathic hyper- eosinophilic syndrome显示文摘 | Jos6 M Pardal F Lourdes SM | 2012 | Revista de Neurologia2012，54，2： | 1 |
| 18 | Chemical studies of anthocyanins:A review 显示文摘 | Castaneda-Ovando A Lourdes Pacheco-Hern:mdez M P6ez-Hern6ndez M | 2009 | Food Chemistry2009，113，4： | 1 |
| 19 | Quintans-riveiro rheological behavionr of galician honeys显示文摘 | DIEGO G D NAVAZA J M LOURDES C | 2006 | Eur Food Res Technol2006，222，： | 1 |
| 20 | The determinants of Spanish industrial exports to the European Union显示文摘 | Kim-Marion Lourdes M | 1997 | Applied Economics1997，，30： | 1 |
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