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160篇 您的检索式:作者名="Lowe H D"
    题名 作者 年代 出处 被引量
1胚胎巨噬细胞和小胶质细胞消融调控小鼠胚胎背根神经节感觉神经元的发育显示文摘众所周知,小胶质细胞可以调节中枢神经系统发育的一些方面。在第11.5天的小鼠胚胎中的小胶质细胞定殖脊髓时,它们与背根神经节感觉神经元(SN)的生长中心轴突相互作用,这表明它们可能在SN发育中发挥一定功能。为了解决这个问题,我们使用缺乏胚胎巨噬细胞(PU.1敲除小鼠)和免疫细胞消融的小鼠胚胎分析胚胎巨噬细胞消融对SNs早期发育的影响。我们发现,除小胶质细胞外,胚胎巨噬细胞还与来自第11.5天的小鼠胚胎的原肌球蛋白受体激酶(Trk)C+感觉神经元,TrkB+感觉神经元和TrkA+感觉神经元外周神经突产生交联。免疫细胞剥夺会导致第11.5天的小鼠胚胎的TrkC+感觉神经元和TrkB+感觉神经元初始数量的减少,这与其发育细胞死亡(DCD)的改变有关联的可能性较小,因为其后在第12.5天的胚胎中的数量有短暂增加。在分析的发育期(第11.5~15.5天),它也导致TrkA+感觉神经元数量减少,尽管我们没有观察到他们的DCD有任何变化。与神经元祖细胞可能存在一致性的脑脂肪酸结合蛋白(BFABP-)阴性细胞的增殖在第11.5天的胚胎中增加,而它们的增殖在第12.5天的胚胎减少,这可部分解释从11.5 d观察到的SN亚型产生的改变。此外,我们观察到在缺乏胚胎巨噬细胞的情况下神经胶质细胞祖细胞(BFABP+细胞)增殖的改变。我们的数据表明,胚胎巨噬细胞和小胶质细胞消融调控SN的发育。Angelim MKSC Maia LMSS Mouffle C Ginhoux F Low D Amancio-Dos-Santos A Makhoul J Le Corronc H Mangin JM Legendre P 聂昊(编译) 2018神经损伤与功能重建2018,13,9:2
2Thermal cycling analysis of flip-chip solder joint reliability 显示文摘Pang J H L Chong D Y R Low T H 2001Components and Packaging Technologies2001,24,4:1
3The relative importance of non-sea-salt sulphate and sea-salt aerosol to the marine cloud condensation nuclei population:Animproved multi-component aerosol-cloud droplet parametrization显示文摘O'Dowd C D Lowe J A Smith M H 1999Quart J Roy Meteor Soc1999,125,556:1
4Optimization Flow Control, I: Basic Algorithm and Convergence显示文摘Low S H Lapsley D E 1999IEEE/ACM Trans on Networking1999,7,6:1
5Optimal flow control I: basic algorithm and convergence 显示文摘Low S H Lapsley D E 1999IEEE/ACM Transactions on Networking1999,7,6:1
6Are overconfident CEOs better innovators显示文摘HIRSHLEIFER D LOW A TEOH S H 2012The Journal of Finance2012,67,4:1
7Production of soluble triggering receptor expressed on myeloid cells by lipopolysaccharide-stimulated human neutrophils involves de novo protein synthesis显示文摘MAHDY A M LOWES D A GALLEY H F 2006Clin Vaccine Immunol2006,13,4:1
8Primary structure of thymosin beta 12, a new member of the beta- thymosin family isolated from perch liver 显示文摘Low T L Liu D T Jou J H 1992Arch Biochem Biophys1992,293,1:1
9Optimization flow control. I. Basic algorithm and convergence显示文摘Low H Lapsley D 0,,:1
10Are overconfident CEOs better innovators?显示文摘Hirshleifer D Low A Teoh S H 2012The Journal of Findnce2012,67,4:1
11An experimental modee for the assessment of titanium denture casting techniques显示文摘Low D Besie H moil T 1994Dental Materials Journal1994,13,:1
12Variability in the organisation and management of hospital care for COPD exacerbations in the UK显示文摘Hosker H Anstey K Lowe D 0,,04:1
13Optimization flow control-I:basic algorithm and convergence显示文摘Low S H Lapsley D E 1999IEEE/ACM Trans on Networking1999,7,6:1
14Dual excitation reactive ion etcher for low energy plasma processing显示文摘Goto H H Lowe H D Ohmi T 1992J Vac Sci Technol A1992,10,:1
15Impact of new legislation on presumed consent on organ donation on liver transplant in Singapore: a preliminary analysis 显示文摘Low H Costa M D Prabhakaran K 2006Transplantation2006,82,9:1
16Antimicrobial susceptibility of 15, 644 pathogens from Canadian hospitals: results of the CANWARD 2007-2009 study显示文摘Zhanel G G Adam H J Low D E 2011Diagn Microbiol Infect Dis2011,69,3:1
17Optimization flow control Ⅰ:basic algorithm and convergence显示文摘Low S H Lapsley D E 1999IEEE/ACM Transactions on Networking1999,7,6:1
18Contaminant-induced lysosomal membrane damage in blood cells of musselsMytilus galloprovincialis from the Venice Lagoon : A in vitrostudy 显示文摘LOWE D M FOSSATO V U DEPLEDGE M H 1995Marine Ecology Progress Series1995,129,123:1
19Comparison of intensity modulated radiation therapy (IMRT) treatment technique for nasopharyngeal carcinoma显示文摘Cheng J C H Chao K S C Low D 2001Int J Cancer2001,96,2:1
20Fast TCP:motivation,architecture,algorithms,performance显示文摘Jin Cheng Wei D X Low S H 2006IEEE/ACM Transactions on Networking2006,14,6:1
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