|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Arginine methylation of ribose-5-phosphate isomerase A senses glucose to promote human colorectal cancer cell survival显示文摘Cancer cells remodel their metabolic network to adapt to variable nutrient availability. Pentose phosphate pathway(PPP) plays protective and biosynthetic roles by oxidizing glucose to generate reducing power and ribose. How cancer cells modulate PPP activity in response to glucose supply remains unclear. Here we show that ribose-5-phosphate isomerase A(RPIA), an enzyme in PPP, directly interacts with co-activator associated arginine methyltransferase 1(CARM1) and is methylated at arginine 42(R42). R42 methylation up-regulates the catalytic activity of RPIA. Furthermore, glucose deprivation strengthens the binding of CARM1 with RPIA to induce R42 hypermethylation. Insufficient glucose supply links to RPIA hypermethylation at R42, which increases oxidative PPP flux. RPIA methylation supports ROS clearance by enhancing NADPH production and fuels nucleic acid synthesis by increasing ribose supply. Importantly, RPIA methylation at R42 significantly potentiates colorectal cancer cell survival under glucose starvation. Collectively, RPIA methylation connects glucose availability to nucleotide synthesis and redox homeostasis. | Jizheng Guo Qixiang Zhang Ying Su Xiaochen Lu Yiping Wang Miao Yin Weiguo Hu Wenyu Wen Qun-Ying Lei | 2020 | Science China(Life Sciences)2020，63，9： | 2 |
| 2 | 查看详情显示文摘 | Hao Yanjing Lai Qiongyu Lu Jizheng | | 0，，02： | 1 |
| 3 | Study of preparation and properties on magnetization and stability for ferromagnetic fluids materials显示文摘 | LAI Qiongyu LU Jizheng JI Xiaoyang | 2000 | Chemistry and Physics2000，66，： | 1 |
| 4 | Study of preparation and properties on magnetization and stability for ferromagnetic fluids显示文摘 | Lai Qiongyu Lu Jizheng Ji Xiaoyang | 2000 | Materials Chemistry and Physics2000，66，1： | 1 |
| 5 | Systhesis and characterization of spinel Li4 Ti5 O12 anode material by oxalic acid-assisted sol-gel method 显示文摘 | HAO Yanjing LAI Qiongyu LU Jizheng | 2006 | Journal of Power Sources2006，158，： | 1 |
| 6 | Systhesis and characterization of spinel Li4Ti5O anode material by oxalic acid-assisted sol-gel method 显示文摘 | HAO Yanjing LAI Qiongyu LU Jizheng | 2006 | Journal of Power Sources2006，158，： | 1 |
| 7 | Synthesis and Characterization of Spinel Li4Ti5O12 Anode Material By Oxalic Acid-Assisted Sol-Gel Method 显示文摘 | HAO Yanjing LAI Qiongyu LU Jizheng | 2006 | Journal of Power Sources2006，158，： | 1 |
| 8 | Synthesis and characterization of spinel Li4 Ti5O12 anode material by oxalic acid-assisted sol-gel method 显示文摘 | Hao Yanjing Lai Qiongyu Lu Jizheng | 2006 | J Power Sources2006，158，： | 1 |
| 9 | Synthesis by TEA sol-gel method and electrochemical properties of Li4Ti5O12 anode material for lithium-ion battery显示文摘 | Hao Yanjing Lai Qiongyu Lu Jizheng | 2005 | Solid State Ionics2005，176，： | 1 |
| 10 | Study of preparation and properties on magnetization and stability for ferromagnetic fluids显示文摘 | Lai Qiongyu Lu Jizheng Ji Xiaoyang | 2000 | Materials Chemistry and Physics2000，66，： | 1 |
| 11 | Study on the stability of magnetic fluids显示文摘 | Lai Qiongyu Lu Jizheng Ji Xiaoyang | 2000 | Materials Chemistry and Physiccs2000，66，： | 1 |
| 12 | Synthesis mechanism of LiNiVO_4 by wet chemical method and mixed valence of nickel and vanadium显示文摘The single phase LiNiVO4 has been successfully synthesized by adopting a new mild liquid route with oxalic acid as both complexant and precipitant, and this method is named the CPG method. The products were obtained by sintering the dry gel precursor which was prepared by the CPG method at 200-850°C for 2-10 h in air. The products were tested by XRD, XPS, ESR and TGA-DTA, and the results indicate that the single phase LiNiVO4 could be obtained at 450°C for 2-3 h in air and LiNiVO4 was still steady at 850°C for 10 h. The valence analyses show that in LiNiVO4 the valence of lithium is +1, both nickel and vanadium have the mixed valence, namely +2, +3 for nickel and +4, +5 for vanadium respectively. The LiNiVO4 can be expressed as LiNi3+xNi2+1-xV4+xV5+1-xO4 (O≤x<1). The pyrolysis mechanism of the dry gel is also discussed. | LAI Qiongyu, LU Jizheng, Jl Xiaoyang, YAN Fangyong, WEI Yongqiang & YU DingChemical College, Sichuan University, Chengdu 610064, China Analytical and Testing Center, Sichuan University, Chengdu 610064, China | 2002 | Chinese Science Bulletin2002，47，6： | 1 |
| 13 | Seasonal dynamic changes in bacterial compositions in the Inner Mongolia desert steppe显示文摘Polymerase chain reaction-denaturing gradient gel electrophoresis(PCR-DGGE)technique was employed to examine the seasonal dynamic changes in bacterial community composition in the Inner Mongolia desert steppe using specific primers F954 and R1369.Bright and reproducible bands were sequenced,and the phylogenic tree was constructed.The results show that the bacterial community composition changed between different seasons.The specific bands were different between the sampling sites with light and heavy levels of degraded grassland.Three main types of bacteria constituting the microbial community in the Inner Mongolia desert steppe belonged to the α,γ and δ-sub phyla of Proteobacteria,Bacteroidetes and Acidobacteria.The unculturable bacteria accounted for 69%of the whole bacterial community of the Inner Mongolia desert steppe. | Ping LU Wanli MA Hao LI Yongsheng WU Guifen LV Jizheng HE | 2009 | Frontiers in Biology2009，4，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员